Reactome | Association of multimerized Rev with beta-importin

Association of multimerized Rev with beta-importin

Stable Identifier

R-HSA-180709

Type

Reaction [binding]

Species

Homo sapiens

Related Species

Human immunodeficiency virus 1

Compartment

cytosol

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - HIV Infection (Homo sapiens)
      - Host Interactions of HIV factors (Homo sapiens)
        
        Interactions of Rev with host cellular proteins (Homo sapiens)
        
        Nuclear import of Rev protein (Homo sapiens)
        
        Association of multimerized Rev with beta-importin (Homo sapiens)

General

SBML | | PDF

SVG | | PPTX | SBGN

Association of multimerized Rev with beta-importin

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The association of Rev with importin-beta is mediated by the Rev nuclear localisation signal.

Literature References

PubMed ID	Title	Journal	Year
9405152	Interactions between HIV Rev and nuclear import and export factors: the Rev nuclear localisation signal mediates specific binding to human importin-beta Henderson, BR, Percipalle, P	J Mol Biol	1997

Participants

Input

Output

Importin beta-1:Rev multimer complex [cytosol] (Homo sapiens)

Participates

as an event of

Nuclear import of Rev protein (Homo sapiens)

Disease

Name	Identifier	Synonyms
Human immunodeficiency virus infectious disease	DOID:526	HIV infection

Authored

Matthews, L (2006-06-08)

Reviewed

Kumar, A (2007-02-01)

Created

Matthews, L (2006-06-02)

Cite Us!