Rev:importin beta:B23 recruited to the nuclear pore

Stable Identifier
R-HSA-180710
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
cytosol, nuclear envelope
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Rev:importin beta:B23 recruited to the nuclear pore
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The Rev-importin beta-B23 complex is recruited to the nuclear pore by an interaction between importin beta and nucleoporin.
Literature References
PubMed ID Title Journal Year
2017166 Specific complex of human immunodeficiency virus type 1 rev and nucleolar B23 proteins: dissociation by the Rev response element

Wingfield, P, Adachi, Y, Fankhauser, C, Laemmli, UK, Izaurralde, E

Mol Cell Biol 1991
9092824 Nucleolar protein B23 stimulates nuclear import of the HIV-1 Rev protein and NLS-conjugated albumin

Mehrotra, B, Wingfield, PT, Baumann, A, Szebeni, A, Olson, MO, Adam, SA

Biochemistry 1997
Participants
Input
Output
Participates
as an event of
Inferred From
Translocation of Rev:importin-beta:B23 to the nucleus (Homo sapiens)
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Matthews, L  (2006-06-08)
Reviewed
Kumar, A  (2007-02-01)
Created
Matthews, L  (2006-06-02)
Cite Us!