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AP2M1 [cytosol]
Stable Identifier
R-HSA-182227
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Plasma membrane adaptor AP-2 50 kDa protein, AP-2 complex subunit mu, AP-2 mu 2
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPH-ephrin mediated repulsion of cells (Homo sapiens)
Clathrin internalises EPH:EFN complexes (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPHB:EFNB:F-actin:AP-2:Clathrrin:Dynamin [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
Host Interactions of HIV factors (Homo sapiens)
The role of Nef in HIV-1 replication and disease pathogenesis (Homo sapiens)
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters (Homo sapiens)
Nef Mediated CD4 Down-regulation (Homo sapiens)
Degradation of CD4 (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Internalized CD4:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPase [early endosome membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Formation of CD4:Nef:AP-2 Complex:v-ATPase Complex (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
CD4:Nef:AP-2 Complex:v-ATPase Complex [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Internalization of the CD4:Nef:AP-2 Complex:v-ATPase Complex (Homo sapiens)
CD4:Nef:AP-2 Complex:v-ATPase Complex [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Internalized CD4:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPase [early endosome membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Nef Mediated CD8 Down-regulation (Homo sapiens)
Degradation of CD8 (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Internalized CD8:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPase [early endosome membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Formation of CD8:Nef:AP-2 Complex:v-ATPase Complex (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
CD8:Nef:AP-2 Complex:v-ATPase Complex [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Internalization of the CD8:Nef:AP-2 Complex:v-ATPase Complex (Homo sapiens)
CD8:Nef:AP-2 Complex:v-ATPase Complex [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Internalized CD8:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPase [early endosome membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Nef mediated downregulation of CD28 cell surface expression (Homo sapiens)
Internalization of Nef:CD28:Clathrin-Coated Pit Adapter Protein Complex (Homo sapiens)
CD28:Nef:Clathrin-coated Pit Adapter Protein [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
Potential therapeutics for SARS (Homo sapiens)
AP2 binds chlorpromazine (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
AP2:chlorpromazine [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
PCP/CE pathway (Homo sapiens)
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Homo sapiens)
FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Homo sapiens)
clathrin:AP-2 [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
WNT5A-dependent internalization of FZD4 (Homo sapiens)
WNT5A:FZD4 is endocytosed (Homo sapiens)
WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane] (Homo sapiens)
clathrin:AP-2 [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Homo sapiens)
WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane] (Homo sapiens)
clathrin:AP-2 [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
clathrin:AP-2 [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
AAK1 phosphorylates AP-2 mu subunit at T156 (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
BAR domain proteins recruit dynamin (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
AP-2 directly binds some endocytic cargo (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
AP2:chlorpromazine [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
AP2 binds chlorpromazine (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
AP2:chlorpromazine [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Clathrin recruits PIK3C2A (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Clathrin recruits auxilins to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Dissociation of clathrin-associated proteins (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Endophilins recruit synaptojanins to the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
FCHo proteins bind nascent clathrin-coated pit (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Initial binding of AP-2 and clathrin to PI(4,5)P2 (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
RAB5 and GAPVD1 bind AP-2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
Recruitment of AP-2 complex and clathrin (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
SNX9 recruits components of the actin polymerizing machinery (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
AP-2:cargo [plasma membrane] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
AP2M1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96CW1 AP2M1
Gene Names
AP2M1, CLAPM1, KIAA0109
Chain
chain:1-435
Reference Genes
COSMIC (genes):AP2M1 AP2M1
dbSNP Gene:1173 AP2M1
ENSEMBL:ENSG00000161203 AP2M1
Participates
as a component of
CD28:Nef:Clathrin-coated Pit Adapter Protein [cytosol] (Homo sapiens)
AP-2 Complex [cytosol] (Homo sapiens)
Other forms of this molecule
AP2M1 [plasma membrane]
AP2M1 [lysosomal membrane]
AP2M1 [clathrin-coated endocytic vesicle membrane]
AP2M1 [endolysosome membrane]
p-T156 AP2M1 [cytosol]
Inferred To
Homologues of AP2M1 [cytosol]
(Danio rerio)
dpy-23 [cytosol]
(Caenorhabditis elegans)
apm2 [cytosol]
(Dictyostelium discoideum)
AP2M1 [cytosol]
(Bos taurus)
AP2M1 [cytosol]
(Canis familiaris)
AP2M1 [cytosol]
(Danio rerio)
AP2M1 [cytosol]
(Drosophila melanogaster)
AP2M1 [cytosol]
(Gallus gallus)
AP2M1 [cytosol]
(Mus musculus)
AP2M1 [cytosol]
(Plasmodium falciparum)
AP2M1 [cytosol]
(Rattus norvegicus)
AP2M1 [cytosol]
(Sus scrofa)
AP2M1 [cytosol]
(Xenopus tropicalis)
APM4 [cytosol]
(Saccharomyces cerevisiae)
apm4 [cytosol]
(Schizosaccharomyces pombe)
Interactors (62)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q7Z3C6 ATG9A
1
ATG9A [phagophore assembly site membrane]
(R-HSA-5671732)
0.895
22
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.828
8
UniProt:P63010 AP2B1
4
AP2B1 [endolysosome membrane]
(R-HSA-6784827)
AP2B1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130489)
AP2B1 [cytosol]
(R-HSA-182166)
AP2B1 [plasma membrane]
(R-HSA-167690)
0.809
7
UniProt:Q15311 RALBP1
1
RALBP1 [cytosol]
(R-HSA-195194)
0.76
7
UniProt:Q92609 TBCD5
0.737
4
UniProt:P42566 EPS15
2
p-Y849 EPS15 [cytosol]
(R-HSA-8867028)
EPS15 [cytosol]
(R-HSA-182920)
0.725
7
UniProt:Q2M2I8 AAK1
1
AAK1 [cytosol]
(R-HSA-8854795)
0.725
6
UniProt:Q68CQ4 UTP25
1
DIEXF [nucleoplasm]
(R-HSA-6790689)
0.666
7
UniProt:Q9UHP6 RSP14
0.666
6
UniProt:P51116 FXR2
0.653
3
UniProt:P49757 NUMB
1
NUMB [plasma membrane]
(R-HSA-443595)
0.643
6
UniProt:O15084 ANKRD28
2
ANKRD28 [cytosol]
(R-HSA-5685714)
ANKRD28 [nucleoplasm]
(R-HSA-9686571)
0.643
3
UniProt:Q15811 ITSN1
1
ITSN1 [cytosol]
(R-HSA-3006481)
0.643
5
UniProt:P53680 AP2S1
4
AP2S1 [endolysosome membrane]
(R-HSA-6784821)
AP2S1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130707)
AP2S1 [cytosol]
(R-HSA-182197)
AP2S1 [plasma membrane]
(R-HSA-389382)
0.643
5
UniProt:Q8NC96 NECAP1
3
NECAP1 [cytosol]
(R-HSA-8863464)
NECAP1 [Golgi membrane]
(R-HSA-434327)
NECAP1 [cytoplasmic vesicle membrane]
(R-HSA-434218)
0.643
3
UniProt:Q9NVZ3 NECAP2
1
NECAP2 [cytosol]
(R-HSA-8863466)
0.643
5
UniProt:P29353 SHC1
5
p-Y-SHC1 [cytosol]
(R-HSA-162568)
SHC1 [cytosol]
(R-HSA-74680)
p-Y349,Y350,Y427-SHC1 [cytosol]
(R-HSA-912321)
p-Y349,Y350-SHC1 [cytosol]
(R-HSA-180276)
p-Y427-SHC1 [cytosol]
(R-HSA-74684)
0.643
5
UniProt:O94973 AP2A2
6
AP2A2(1-939) [endolysosome membrane]
(R-HSA-6784819)
AP2A2(1-939) [secretory granule membrane]
(R-HSA-6800412)
AP2A2(1-939) [ficolin-1-rich granule membrane]
(R-HSA-6800414)
AP2A2(1-939) [clathrin-coated endocytic vesicle membrane]
(R-HSA-5138448)
AP2A2(1-939) [cytosol]
(R-HSA-182155)
AP2A2(1-939) [plasma membrane]
(R-HSA-177502)
0.643
5
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.569
9
UniProt:Q9NZ81 PRR13
0.556
3
UniProt:Q9P0T4 ZN581
0.556
3
UniProt:Q86YD7 F90A1
0.556
5
UniProt:Q1ED39 KNOP1
0.556
3
UniProt:Q99880 H2BC13
9
Ub-HIST1H2BL [nucleoplasm]
(R-HSA-6782543)
AcK-HIST1H2BL [nucleoplasm]
(R-HSA-4549254)
HIST1H2BL [extracellular region]
(R-HSA-977579)
AcK13-HIST1H2BL [nucleoplasm]
(R-HSA-4568650)
AcK16-HIST1H2BL [nucleoplasm]
(R-HSA-4568697)
AcK6-HIST1H2BL [nucleoplasm]
(R-HSA-4568719)
AcK21-HIST1H2BL [nucleoplasm]
(R-HSA-4568674)
Ub-121-HIST1H2BL [nucleoplasm]
(R-HSA-3364013)
HIST1H2BL [nucleoplasm]
(R-HSA-181920)
0.556
3
UniProt:Q9BU76 MMTAG2
3
MMTAG2 [ficolin-1-rich granule lumen]
(R-HSA-6801074)
MMTAG2 [extracellular region]
(R-HSA-6806452)
MMTAG2 [secretory granule lumen]
(R-HSA-6801073)
0.556
3
UniProt:Q03393 PTS
2
PTS [cytosol]
(R-HSA-1475061)
p-S19-PTS [cytosol]
(R-HSA-1475426)
0.556
3
UniProt:Q99633 PRPF18
1
PRPF18 [nucleoplasm]
(R-HSA-5688093)
0.556
3
UniProt:P0DPH9 CX05B
0.556
3
UniProt:Q96JC9 EAF1
1
EAF1 [nucleoplasm]
(R-HSA-8932787)
0.556
5
UniProt:Q00013 MPP1
1
MPP1 [plasma membrane]
(R-HSA-420423)
0.556
5
UniProt:P55081 MFAP1
1
MFAP1 [nucleoplasm]
(R-HSA-2396419)
0.556
3
UniProt:P62807 H2BC4
9
HIST1H2BC [nucleoplasm]
(R-HSA-181906)
Ub-121-HIST1H2BC [nucleoplasm]
(R-HSA-3364029)
AcK21-HIST1H2BC [nucleoplasm]
(R-HSA-4568626)
AcK13-HIST1H2BC [nucleoplasm]
(R-HSA-4568620)
AcK6-HIST1H2BC [nucleoplasm]
(R-HSA-4568623)
AcK16-HIST1H2BC [nucleoplasm]
(R-HSA-4568634)
HIST1H2BC [extracellular region]
(R-HSA-977564)
AcK-HIST1H2BC [nucleoplasm]
(R-HSA-4549246)
Ub-HIST1H2BC [nucleoplasm]
(R-HSA-6782552)
0.556
5
UniProt:Q8N8X9 MB213
0.556
5
UniProt:Q96EY4 TMA16
0.556
3
IntAct:EBI-16429620 CCSB ORF ID
0.556
3
UniProt:Q8N9N8 EIF1A
0.556
3
UniProt:Q6ZUT1 NKAP1
0.556
3
UniProt:Q8NAV1 PRPF38A
1
PRPF38A [nucleoplasm]
(R-HSA-8867897)
0.556
5
UniProt:Q8N3F0 MTURN
0.556
3
UniProt:Q9BSU3 NAA11
0.556
3
UniProt:P35268 RPL22
1
RPL22 [cytosol]
(R-HSA-72428)
0.556
3
UniProt:Q96MH2 HEXI2
0.556
3
UniProt:Q16778 H2BC21
9
HIST2H2BE [nucleoplasm]
(R-HSA-181908)
Ub-121-HIST2H2BE [nucleoplasm]
(R-HSA-3364018)
AcK16-HIST2H2BE [nucleoplasm]
(R-HSA-4568660)
AcK6-HIST2H2BE [nucleoplasm]
(R-HSA-4568679)
AcK21-HIST2H2BE [nucleoplasm]
(R-HSA-4568716)
AcK13-HIST2H2BE [nucleoplasm]
(R-HSA-4568651)
HIST2H2BE [extracellular region]
(R-HSA-977571)
Ack-HIST2H2BE [nucleoplasm]
(R-HSA-4549257)
Ub-HIST2H2BE [nucleoplasm]
(R-HSA-6782539)
0.556
3
UniProt:O14641 DVL2
5
DVL2 [cytosol]
(R-HSA-201694)
pp-DVL2 [cytosol]
(R-HSA-3772398)
p-DVL2 [cytosol]
(R-HSA-201706)
p-DVL2 [clathrin-coated endocytic vesicle]
(R-HSA-5138444)
ub-DVL2 [cytosol]
(R-HSA-4652689)
0.553
2
UniProt:Q59EK9 RUN3A
0.547
3
UniProt:Q77IS8 NCAP
0.544
2
UniProt:P27958-PRO_0000037566
0.543
4
UniProt:P57739 CLDN2
2
CLDN2 [plasma membrane]
(R-HSA-419994)
CLDN2 [cell junction]
(R-HSA-421235)
0.537
4
UniProt:P11274 BCR
4
BCR [cytosol]
(R-HSA-195200)
BCR(1-584)-FGFR1(429-822) fusion [cytosol]
(R-HSA-1604524)
p-Y177-BCR(1-584)-p-FGFR1(429-822) fusion [cytosol]
(R-HSA-1839041)
BCR(1-584)-p-FGFR1(429-822) fusion [cytosol]
(R-HSA-1838979)
0.527
3
UniProt:O95782 AP2A1
5
AP2A1 [endolysosome membrane]
(R-HSA-6784829)
AP2A1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-5138449)
AP2A1 [cytosol]
(R-HSA-182143)
AP2A1 [plasma membrane]
(R-HSA-177494)
AP2A1 [endocytic vesicle membrane]
(R-HSA-416641)
0.527
4
UniProt:P0DTD1-PRO_0000449628 REP
0.527
2
UniProt:Q0JRZ9 FCHO2
1
FCHO2 [cytosol]
(R-HSA-8862260)
0.527
3
UniProt:Q10567 AP1B1
5
AP1B1 [cytoplasmic vesicle membrane]
(R-HSA-351181)
AP1B1 [Golgi membrane]
(R-HSA-350809)
AP1B1 [lysosomal membrane]
(R-HSA-432699)
AP1B1 [trans-Golgi network membrane]
(R-HSA-2130596)
AP1B1 [cytosol]
(R-HSA-167705)
0.527
4
UniProt:Q16626 MEA1
0.527
4
UniProt:P22626 HNRNPA2B1
2
HNRNPA2B1 [nucleoplasm]
(R-HSA-71929)
HNRNPA2B1 [extracellular exosome]
(R-HSA-8950304)
0.527
2
UniProt:Q9UBC2 EPS15L1
2
EPS15L1 [plasma membrane]
(R-HSA-182937)
EPS15L1 [cytosol]
(R-HSA-8935900)
0.527
4
UniProt:Q96D71 REPS1
1
REPS1 [cytosol]
(R-HSA-8862265)
0.527
4
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:P18272 NCAP
0.524
2
UniProt:Q01968 OCRL
4
OCRL [Golgi membrane]
(R-HSA-434339)
OCRL [cytoplasmic vesicle membrane]
(R-HSA-434214)
OCRL [plasma membrane]
(R-HSA-3769049)
OCRL [cytosol]
(R-HSA-1806196)
0.508
3
UniProt:P51114 FXR1
2
FXR1(2-784)-BRAF(381-766) fusion [cytosol]
(R-HSA-6802326)
FXR1(2-784)-p-BRAF(381-766) fusion [cytosol]
(R-HSA-6802530)
0.508
2
UniProt:A9UF07 A9UF07
0.462
2
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