Phosphorylation of CBL (EGFR:CBL)

Stable Identifier
R-HSA-182969
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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EGF (and indeed FGF, PDGF and NGF) stimulation results in CBL phosphorylation on Tyr-371. Phosphorylation is necessary for CBL to exhibit ubiquitin ligase activity.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of EGF-like ligands:p-6Y-EGFR:CBL [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created