CBL binds multiple signalling proteins including GRB2. The CBL:GRB2 complex translocates to the plasma membrane where it can bind to GRB2-specific docking sites on the EGF receptor.
Panchamoorthy, G, Fukazawa, T, Miyake, S, Soltoff, S, Reedquist, K, Druker, B, Shoelson, S, Cantley, LC, Band, H
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