ZMYM2-p-2Y-FGFR1 fusion [cytosol]

Stable Identifier
R-HSA-1839016
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
ZMYM2(1-913)-p-FGFR1(429-822) fusion, t(8;13) ZMYM2-p-FGFR1 fusion, ZNF198-p-FGFR1 fusion, ZNF198(1-913)-p-FGFR1(429-822) fusion, t(8;13) ZNF198-p-FGFR1 fusion, FIM-p-FGFR1 fusion, RAMP-p-FGFR1 fusion
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
9716603 Consistent fusion of ZNF198 to the fibroblast growth factor receptor-1 in the t(8;13)(p11;q12) myeloproliferative syndrome

Reiter, A, Sohal, J, Kulkarni, S, Chase, A, Macdonald, DH, Aguiar, RC, Gonçalves, C, Hernandez, JM, Jennings, BA, Goldman, JM, Cross, NC

Blood 1998
9425908 FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome

Xiao, S, Nalabolu, SR, Aster, JC, Ma, J, Abruzzo, L, Jaffe, ES, Stone, R, Weissman, SM, Hudson, TJ, Fletcher, JA

Nat Genet 1998
9576949 Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13)

Popovici, C, Adelaide, J, Ollendorff, V, Chaffanet, M, Guasch, G, Jacrot, M, Leroux, D, Birnbaum, D, Pébusque, MJ

Proc Natl Acad Sci U S A 1998
External Reference Information
External Reference
UniProt:Q9UBW7 ZMYM2
Gene Names
ZMYM2, FIM, RAMP, ZNF198
Chain
chain:1-1377
Reference Genes
BioGPS Gene:7750 ZMYM2
COSMIC (genes):ZMYM2 ZMYM2
CTD Gene:7750 ZMYM2
dbSNP Gene:7750 ZMYM2
ENSEMBL:ENSG00000121741 ZMYM2
HGNC:12989 ZMYM2
KEGG Gene (Homo sapiens):7750 ZMYM2
Monarch:7750 ZMYM2
NCBI Gene:7750 ZMYM2
OMIM:602221 ZMYM2
UCSC:Q9UBW7 ZMYM2
Reference Transcript
Other Identifiers
0006420609
11739414_a_at
11752025_s_at
11759305_at
11759306_s_at
16772942
202778_s_at
210281_s_at
226512_at
240642_at
242597_at
31765
3480131
3480132
3480133
3480134
3480138
3480141
3480147
3480148
3480149
3480150
3480153
3480154
3480155
3480156
3480157
3480162
3480163
3480165
3480166
3480167
3480168
3480171
3480172
3480173
3480174
3480175
3480176
3480177
3480179
3480182
3480185
3480186
3480187
3480194
3480196
3480197
3480199
3480201
3480202
3480203
3480204
3480243
3480244
3480246
3504069
41436_at
45184_at
48606_at
53216_at
62170_at
7750
7967900
85956_at
A0A024RDS3
A0A087X151
A_14_P137536
A_23_P99405
AAB88464
AAC01561
AAC23591
AAH36372
AF012126
AF035374
AF060181
AJ007676
AJ007677
AJ007678
AJ007679
AJ007680
AJ007681
AJ007682
AJ007683
AJ007684
AJ007685
AJ007686
AJ007687
AJ007688
AJ007689
AJ007690
AJ007691
AJ007692
AJ007693
AJ007694
AJ007695
AJ007696
AJ224901
AL136621
AL137119
AL138688
BC036372
BX647944
CAA07604
CAA12204
CAA73875
CAB66556
CAH56193
CAH70133
CAH70134
CAH71822
CCDS45016
CH471075
EAX08244
EAX08245
EAX08246
EAX08247
EAX08248
ENSG00000121741
ENSP00000372324
ENSP00000372327
ENSP00000479904
ENST00000382871
ENST00000382871.3
ENST00000382874
ENST00000382874.6
ENST00000610343
ENST00000610343.4
EntrezGene:7750
EntrezGene:ZMYM2
g4508010_3p_a_at
GE495605
GE55255
GO:0000902
GO:0000981
GO:0003674
GO:0003700
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006357
GO:0008150
GO:0008270
GO:0009058
GO:0016605
GO:0019899
GO:0022604
GO:0031624
GO:0034641
GO:0043167
GO:0043226
GO:0046872
GO:0048856
HGNC:12989
HPA031765
Hs.26490.0.A1_3p_at
Hs.26490.1.A1_3p_at
Hs.41167.0.A1_3p_at
ILMN_1661636
ILMN_2403823
IPR010507
IPR011017
IPR021893
MIM:602221
NM_001190964
NM_001190965
NM_001353157
NM_001353159
NM_001353161
NM_001353162
NM_001353163
NM_001353164
NM_001353165
NM_003453
NM_197968
NP_001177893
NP_001177894
NP_001340086
NP_001340088
NP_001340090
NP_001340091
NP_001340092
NP_001340093
NP_001340094
NP_003444
NP_932072
NR_148365
PF06467
PF12012
PH_hs_0029730
SM00746
TC13000021.hg
TC13000927.hg
UPI000013C318
XM_005266520
XM_011535222
XM_011535223
XM_017020731
XM_017020732
XM_017020733
XM_017020734
XM_017020735
XM_017020737
XM_024449406
XM_024449407
XP_005266577
XP_011533524
XP_011533525
XP_016876220
XP_016876221
XP_016876222
XP_016876223
XP_016876224
XP_016876226
XP_024305174
XP_024305175
XR_001749659
XR_001749660
XR_941650
XR_941652
Y13472
ZMYM2
ZMYM2-202
ZMYM2-203
ZMYM2-210
ZNF198
Participant Of
hasComponent
Other forms of this molecule
ZMYM2-FGFR1 fusion [cytosol]
Modified Residues
Name
Insertion of residues 429 to 822 at 914 from UniProt:P11362 FGFR1
Coordinate
914
Name
O4'-phospho-L-tyrosine at 766
Coordinate
766
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at unknown position
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
precursor lymphoblastic lymphoma/leukemia 5600
subacute leukemia 3264
myelodysplastic myeloproliferative cancer 4972 Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Interactors (4)