Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex

Stable Identifier
R-HSA-184269
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
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Monoubiquitinated N-myristoyl Gag polyprotein associates with the ESCRT-1 complex at an endosomal membrane (Eastman et al. 2005; Martin-Serrano et al. 2003; Stuchell et al. 2004).

Literature References
PubMed ID Title Journal Year
12663786 Role of ESCRT-I in retroviral budding

Martin-Serrano, J, Zang, T, Bieniasz, PD

J Virol 2003
15218037 The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding

Stuchell, MD, Garrus, JE, Muller, B, Stray, KM, Ghaffarian, S, McKinnon, R, Krausslich, HG, Morham, SG, Sundquist, WI

J Biol Chem 2004
15509564 Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding

Eastman, SW, Martin-Serrano, J, Chung, W, Zang, T, Bieniasz, PD

J Biol Chem 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein transmembrane transporter activity of ESCRT-I [endosome membrane]
Physical Entity
Activity
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease 526 HIV infection
Authored
Reviewed
Created