I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol

Stable Identifier
R-HSA-1855159
Type
Reaction
Species
Homo sapiens
Compartment
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Summation

Inositol-tetrakisphosphate 1-kinase (ITPK1) dephosphorylates inositol 1,3,4,6-tetrakisphosphate (I(1,3,4,6)P4) to inositol 3,4,6-trisphosphate (I(3,4,6)P3) (Ho et al. 2002).

Literature References
PubMed ID Title Journal Year
11909533 Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase

Ho, MW, Yang, X, Carew, MA, Zhang, T, Hua, L, Kwon, YU, Chung, SK, Adelt, S, Vogel, G, Riley, AM, Potter, BV, Shears, SB

Curr Biol 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity of ITPK1:Mg2+ [cytosol]
Physical Entity
Activity
Orthologous Events
Authored