I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol

Stable Identifier
R-HSA-1855162
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Inositoltetrakisphosphate 1-kinase (ITPK1) phosphorylates inositol 3,4,5,6-tetrakisphosphate (I(3,4,5,6)P4) to inositol 1,3,4,5,6-pentakisphosphate (I(1,3,4,5,6)P5) (Yang & Shears 2000).
Literature References
PubMed ID Title Journal Year
11042108 Multitasking in signal transduction by a promiscuous human Ins(3,4,5,6)P(4) 1-kinase/Ins(1,3,4)P(3) 5/6-kinase

Yang, X, Shears, SB

Biochem J 2000
Participants
Participates
Catalyst Activity

inositol tetrakisphosphate 1-kinase activity of ITPK1:Mg2+ [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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