I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol

Stable Identifier
R-HSA-1855171
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Inositol-tetrakisphosphate 1-kinase (ITPK1) dephosphorylates inositol 1,3,4,6-tetrakisphosphate (I(1,3,4,6)P4) to inositol 1,3,4-trisphosphate (I(1,3,4)P3) (Ho et al. 2002).

Literature References
PubMed ID Title Journal Year
11909533 Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase Curr Biol 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity of ITPK1:Mg2+ [cytosol]
Physical Entity
Activity
Orthologous Events