p-6Y-SYK [cytosol]

Stable Identifier
R-HSA-1861712
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Tyrosine-protein kinase SYK , Spleen tyrosine kinase
p-6Y-SYK [cytosol] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
SYK
Chain
chain:1-635
Other Identifiers
11719718_a_at
11754925_a_at
1630_s_at
17086708
207540_PM_s_at
207540_s_at
209269_PM_s_at
209269_s_at
226068_PM_at
226068_at
3178954
3178955
3178958
3178959
3178960
3178961
3178964
3178965
3178969
3178971
3178972
3178973
3178977
3178980
3178982
3178984
3178986
3178989
3178994
3178995
3178996
3178997
3178998
36885_at
548_s_at
55564_at
6850
7896689
7896705
8156321
A_14_P110676
A_14_P117239
A_23_P9255
GE57710
GO:0000166
GO:0001525
GO:0001775
GO:0001784
GO:0001819
GO:0001820
GO:0001945
GO:0002092
GO:0002223
GO:0002250
GO:0002281
GO:0002283
GO:0002366
GO:0002376
GO:0002554
GO:0002696
GO:0002862
GO:0003824
GO:0004672
GO:0004674
GO:0004713
GO:0004715
GO:0005102
GO:0005178
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006468
GO:0006606
GO:0006886
GO:0006913
GO:0006954
GO:0007155
GO:0007159
GO:0007166
GO:0007167
GO:0007169
GO:0007229
GO:0009887
GO:0010543
GO:0010803
GO:0012501
GO:0016020
GO:0016170
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0018108
GO:0019370
GO:0019722
GO:0019815
GO:0019901
GO:0019902
GO:0023052
GO:0030154
GO:0030168
GO:0030183
GO:0030593
GO:0031234
GO:0031334
GO:0031410
GO:0031623
GO:0032009
GO:0032481
GO:0032725
GO:0032733
GO:0032735
GO:0032752
GO:0032753
GO:0032755
GO:0032757
GO:0032760
GO:0032765
GO:0032928
GO:0032930
GO:0032991
GO:0033630
GO:0035325
GO:0035556
GO:0036211
GO:0038063
GO:0038095
GO:0038096
GO:0038156
GO:0042060
GO:0042101
GO:0042169
GO:0042492
GO:0042742
GO:0043226
GO:0043274
GO:0043280
GO:0043303
GO:0043306
GO:0043313
GO:0043366
GO:0043410
GO:0043507
GO:0045087
GO:0045579
GO:0045588
GO:0045780
GO:0046638
GO:0046641
GO:0046777
GO:0048514
GO:0048856
GO:0048870
GO:0050731
GO:0050764
GO:0050778
GO:0050850
GO:0050853
GO:0051090
GO:0051649
GO:0051712
GO:0065003
GO:0070372
GO:0071226
GO:0071396
GO:0071404
GO:0071639
GO:0090237
GO:0090330
GO:0097110
GO:0098542
GO:0120162
GO:0140096
GO:1990858
HMNXSV003042953
Hs.74101.1.S2_3p_a_at
Hs.74101.2.S1_3p_a_at
Hs.74101.2.S1_3p_at
ILMN_2059549
PH_hs_0022924
S80267_s_at
TC09000428.hg
g4507328_3p_a_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
O4'-phospho-L-tyrosine at 348
Coordinate
348
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 352
Coordinate
352
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 525
Coordinate
525
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 526
Coordinate
526
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 131
Coordinate
131
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 323
Coordinate
323
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Investigational
ZINC - Metabolites
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (20)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P40763 STAT3  12 0.873 10
 UniProt:Q9UHP3 USP25  1 0.831 8
 UniProt:P06239 LCK  4 0.748 8
 UniProt:P22681 CBL  20 0.743 7
 UniProt:P36888 FLT3  20 0.737 22
 UniProt:P20273 CD22  3 0.623 4
 UniProt:P07766 CD3E  2 0.597 6
 UniProt:Q9ULZ3 PYCARD  4 0.591 4
 UniProt:P27986 PIK3R1  16 0.581 5
 UniProt:Q96IP4 TET5A      0.57 3
 UniProt:P30273 FCER1G  5 0.564 2
 UniProt:Q9NP31 SH2D2A  1 0.556 3
 UniProt:P05067 APP  20 0.556 3
 UniProt:Q8TF42 UBS3B      0.544 2
 UniProt:P54274 TERF1  1 0.508 2
 ChEBI:39112 BOSUTINIB      0.499 2
 UniProt:P11049 CD37      0.499 3
 ChEBI:49375 DASATINIB      0.499 2
 UniProt:P19174 PLCG1  6 0.462 4
 UniProt:Q8TDQ0 HAVCR2  1 0.462 3
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