Synthetic oligodeoxynucleotides (ODN) expressing non-methylated CpG motifs patterned after those present in bacterial DNA have characteristic immunomodulatory effects. CpG DNA is recognized as a pathogen-associated molecular pattern by TLR9, and triggers a rapid innate immune response.
Chockalingam, A, Cameron, JL, Brooks, JC, Leifer, CA
Wagner, H
© 2021 Reactome