Rab5-mediated recruitment of class III PI3K to TLR9

Stable Identifier
R-HSA-188002
Type
Reaction [binding]
Species
Homo sapiens
Compartment
endosome membrane, cytosol
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Rab5-mediated recruitment of class III PI3K to TLR9
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TLR9 signaling has the uncommon property of triggering PI3K-mediated cascades via Rab5.

Literature References
PubMed ID Title Journal Year
17878374 TLR9 activation induces normal neutrophil responses in a child with IRAK-4 deficiency: involvement of the direct PI3K pathway

Hoarau, C, Gérard, B, Lescanne, E, Henry, D, François, S, Lacapère, JJ, El Benna, J, Dang, PM, Grandchamp, B, Lebranchu, Y, Gougerot-Pocidalo, MA, Elbim, C

J. Immunol. 2007
14751759 Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9

Takeshita, F, Gursel, I, Ishii, KJ, Suzuki, K, Gursel, M, Klinman, DM

Semin Immunol 2004
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This event is regulated
Requirements
Orthologous Events
Rab5-mediated recruitment of class III PI3K to TLR9 (Canis familiaris)
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Rab5-mediated recruitment of class III PI3K to TLR9 (Rattus norvegicus)
Rab5-mediated recruitment of class III PI3K to TLR9 (Xenopus tropicalis)
Created
de Bono, B  (2006-09-29)
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