Rab5-mediated recruitment of class III PI3K to TLR9

Stable Identifier
Reaction [binding]
Homo sapiens
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TLR9 signaling has the uncommon property of triggering PI3K-mediated cascades via Rab5.

Literature References
PubMed ID Title Journal Year
14751759 Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9

Klinman, DM, Gursel, M, Ishii, KJ, Suzuki, K, Gursel, I, Takeshita, F

Semin Immunol 2004
17878374 TLR9 activation induces normal neutrophil responses in a child with IRAK-4 deficiency: involvement of the direct PI3K pathway

Lebranchu, Y, François, S, Hoarau, C, Gougerot-Pocidalo, MA, El Benna, J, Dang, PM, Lescanne, E, Grandchamp, B, Gérard, B, Elbim, C, Lacapère, JJ, Henry, D

J. Immunol. 2007
This event is regulated
Orthologous Events
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