Flagellin binds to TLR5

Stable Identifier
R-HSA-188025
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Escherichia coli
Compartment
plasma membrane, extracellular region
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Flagellin binds to TLR5
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Fragments of extracelllar flagellin bind the TLR5 homodimer.

Literature References
PubMed ID Title Journal Year
12807870 Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells

Smith MF, Jr, Mitchell, A, Li, G, Ding, S, Fitzmaurice, AM, Ryan, K, Crowe, S, Goldberg, JB

J Biol Chem 2003
15241424 Inferences, questions and possibilities in Toll-like receptor signalling

Beutler, B

Nature 2004
11323673 The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Hayashi, F, Smith, KD, Ozinsky, A, Hawn, TR, Yi, EC, Goodlett, DR, Eng, JK, Akira, S, Underhill, DM, Aderem, A

Nature 2001
16439799 AsialoGM1 and TLR5 cooperate in flagellin-induced nucleotide signaling to activate Erk1/2

McNamara, N, Gallup, M, Sucher, A, Maltseva, I, McKemy, D, Basbaum, C

Am J Respir Cell Mol Biol 2006
Participants
Input
Output
Participant Of
hasEvent
Reviewed
Gale M, Jr  (2006-10-31)
Gillespie, ME  (2011-02-10)
Created
de Bono, B  (2006-09-30)
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