B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker

Stable Identifier
R-HSA-1889981
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Galactose is the second sugar added in the tetrasaccharide linker
Locations in the PathwayBrowser
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Beta-1,4-galactosyltransferase 7 (B4GALT7) adds galactose (Gal) to beta-xyloside in a beta-1,4 linkage creating the second unit in the formation of the tetrasaccharide linker, the precursor required for glycosaminoglycan (GAG) synthesis (Almeida et al. 1999). Defects in B4GALT7 cause Ehlers-Danlos syndrome progeroid type (EDSP) (MIM:130070) (Okajima et al. 1999).

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
xylosylprotein 4-beta-galactosyltransferase activity of B4GALT7 [Golgi membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created