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SLC2A5 [plasma membrane]
Stable Identifier
R-HSA-189202
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
GLUT5, Solute carrier family 2, facilitated glucose transporter member 5
Icon
Locations in the PathwayBrowser
Expand all
Digestion and absorption (Homo sapiens)
Intestinal absorption (Homo sapiens)
Intestinal hexose absorption (Homo sapiens)
SLC2A5 transports fructose from extracellular region to cytosol (Homo sapiens)
SLC2A5 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
SLC2A5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P22732 SLC2A5
Gene Names
SLC2A5, GLUT5
Chain
chain:1-501
Reference Genes
BioGPS Gene:6518 SLC2A5
COSMIC (genes):SLC2A5 SLC2A5
CTD Gene:6518 SLC2A5
dbSNP Gene:6518 SLC2A5
ENSEMBL:ENSG00000142583 SLC2A5
ENSEMBL_homo_sapiens_GENE:ENSG00000142583.18 SLC2A5
HGNC:11010 SLC2A5
KEGG Gene (Homo sapiens):6518 SLC2A5
Monarch:6518 SLC2A5
NCBI Gene:6518 SLC2A5
OMIM:138230 SLC2A5
UCSC:P22732 SLC2A5
Reference Transcript
RefSeq:XM_017002133.1 SLC2A5
RefSeq:XM_017002141.1 SLC2A5
RefSeq:XM_017002134.1 SLC2A5
RefSeq:XM_017002137.1 SLC2A5
RefSeq:NM_003039.2 SLC2A5
RefSeq:XM_017002138.1 SLC2A5
RefSeq:XM_005263491.3 SLC2A5
RefSeq:NM_001135585.1 SLC2A5
RefSeq:XM_017002135.1 SLC2A5
RefSeq:NM_001328619.1 SLC2A5
RefSeq:XM_017002136.1 SLC2A5
RefSeq:XM_017002140.1 SLC2A5
Other Identifiers
11743848_a_at
11743849_x_at
11746547_a_at
11748758_a_at
11750779_a_at
11753463_a_at
11759017_at
16681408
204429_PM_s_at
204429_s_at
204430_PM_s_at
204430_s_at
230705_PM_at
230705_at
2395565
2395566
2395567
2395568
2395569
2395570
2395571
2395572
2395573
2395574
2395576
2395578
2395579
2395580
2395581
2395582
2395583
2395584
2395585
2395586
2395587
2395588
2395589
2395591
2395592
2395593
2395594
2395596
2395597
2395598
242525_PM_at
242525_at
34362_at
48410_at
6518
7912224
84397_at
A_23_P160159
A_24_P111054
A_33_P3317797
GE57974
GE841923
GO:0003013
GO:0003044
GO:0005215
GO:0005353
GO:0005355
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0005975
GO:0008643
GO:0009750
GO:0015755
GO:0016020
GO:0016324
GO:0022600
GO:0022857
GO:0031410
GO:0035579
GO:0042383
GO:0043226
GO:0055085
GO:0070061
GO:0070062
GO:0071332
GO:0106001
GO:1904659
GO:1990539
HMNXSV003009192
HMNXSV003053317
HMNXSV003057094
Hs.163105.0.A1_3p_at
Hs.33084.0.S1_3p_a_at
Hs.33084.1.S1_3p_at
ILMN_1671337
M55531_at
PH_hs_0039685
TC01002179.hg
TC01005250.hg
g4507012_3p_a_at
Participates
as a member of
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
SLC2A5 [specific granule membrane]
Inferred To
Homologues of SLC2A5 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SLC2A5 [plasma membrane]
(Dictyostelium discoideum)
Homologues of SLC2A5 [plasma membrane]
(Plasmodium falciparum)
Homologues of SLC2A5 [plasma membrane]
(Saccharomyces cerevisiae)
fdgt-2 [plasma membrane]
(Caenorhabditis elegans)
SLC2A5 [plasma membrane]
(Bos taurus)
SLC2A5 [plasma membrane]
(Caenorhabditis elegans)
SLC2A5 [plasma membrane]
(Canis familiaris)
SLC2A5 [plasma membrane]
(Dictyostelium discoideum)
SLC2A5 [plasma membrane]
(Drosophila melanogaster)
SLC2A5 [plasma membrane]
(Gallus gallus)
SLC2A5 [plasma membrane]
(Mus musculus)
SLC2A5 [plasma membrane]
(Plasmodium falciparum)
SLC2A5 [plasma membrane]
(Rattus norvegicus)
SLC2A5 [plasma membrane]
(Saccharomyces cerevisiae)
SLC2A5 [plasma membrane]
(Sus scrofa)
slcf-2 [plasma membrane]
(Caenorhabditis elegans)
symA [plasma membrane]
(Dictyostelium discoideum)
VPS73 [plasma membrane]
(Saccharomyces cerevisiae)
slc2a5 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
XP_005263548.1
,
NP_001315548.1
,
XP_016857623.1
,
XP_016857625.1
,
XP_016857627.1
,
NP_003030.1
,
XP_016857630.1
,
XP_016857626.1
,
XP_016857622.1
,
XP_016857624.1
,
XP_016857629.1
,
NP_001129057.1
Guide to Pharmacology - Targets
880
OpenTargets
ENSG00000142583
HPA
ENSG00000142583-SLC2A5
GeneCards
P22732
Ensembl
ENST00000377414
,
ENST00000377424
,
ENSP00000366641
,
ENSG00000142583
,
ENSP00000366631
PRO
P22732
Pharos - Targets
P22732
HMDB Protein
HMDBP11766
Interactors (15)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75459 PAGE1
0.556
3
UniProt:Q8N3G9 TM130
0.556
3
UniProt:Q9NY72 SCN3B
1
SCN3B [plasma membrane]
(R-HSA-197921)
0.556
3
UniProt:Q96E29 MTERF3
4
Ub-MTERFD1 [mitochondrial outer membrane]
(R-HSA-9843333)
K48polyUb-MTERFD1 [mitochondrial outer membrane]
(R-HSA-5205630)
K63polyUb-MTERFD1 [mitochondrial outer membrane]
(R-HSA-9834044)
p-S65-Ub:MTERFD1 [mitochondrial outer membrane]
(R-HSA-9843337)
0.556
3
UniProt:Q96Q45-2 TMEM237
0.556
3
UniProt:P34910-2 P349102
0.556
3
UniProt:O14880 MGST3
1
MGST3 [endoplasmic reticulum membrane]
(R-HSA-176053)
0.556
3
UniProt:Q96P31-6 Q96P316
0.556
3
UniProt:P21964 COMT
2
COMT [plasma membrane]
(R-HSA-379386)
COMT [cytosol]
(R-HSA-175974)
0.556
3
UniProt:Q99437 ATP6V0B
3
ATP6V0B [endosome membrane]
(R-HSA-912584)
ATP6V0B [phagocytic vesicle membrane]
(R-HSA-1222695)
ATP6V0B [lysosomal membrane]
(R-HSA-9640187)
0.556
3
UniProt:Q3SXY8 ARL13B
8
PolyUb-Misfolded ARL13B [lysosomal lumen]
(R-HSA-9660004)
PolyUb-Misfolded ARL13B [cytosol]
(R-HSA-9641129)
Ub-Misfolded ARL13B [cytosol]
(R-HSA-9641119)
Misfolded ARL13B [cytosol]
(R-HSA-9640110)
Misfolded ARL13B [cilium]
(R-HSA-9640116)
ARL13B [cilium]
(R-HSA-5618181)
PolyUb-Misfolded ARL13B [late endosome lumen]
(R-HSA-9659986)
ARL13B [plasma membrane]
(R-HSA-9716787)
0.556
3
UniProt:Q68DH5 LMBD2
0.527
2
UniProt:Q8N6M3 FITM2
1
FITM2 [endoplasmic reticulum membrane]
(R-HSA-8857678)
0.527
2
UniProt:Q8WY07 SLC7A3
1
SLC7A3 [plasma membrane]
(R-HSA-375779)
0.527
2
UniProt:A6NFN3 RBFOX3
1
RBFOX3 [nucleoplasm]
(R-HSA-9635282)
0.527
2
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