ALAS1 [mitochondrial matrix]

Stable Identifier
R-HSA-189438
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
5-aminolevulinate synthase, non-specific, HEM1_HUMAN, 5-aminolevulinate synthase, non-specific, mitochondrial
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P13196 ALAS1
Gene Names
ALAS1, ALAS3, ALASH, OK/SW-cl.121
Chain
transit peptide:1-56, chain:57-640
Reference Genes
BioGPS Gene:211 ALAS1
COSMIC (genes):ALAS1 ALAS1
CTD Gene:211 ALAS1
dbSNP Gene:211 ALAS1
ENSEMBL:ENSG00000023330 ALAS1
HGNC:396 ALAS1
KEGG Gene (Homo sapiens):211 ALAS1
Monarch:211 ALAS1
NCBI Gene:211 ALAS1
OMIM:125290 ALAS1
Reference Transcript
Other Identifiers
0001450494
00260+2.3.1.37
00860+2.3.1.37
11719328_a_at
11719329_x_at
11733041_a_at
11750973_a_at
16941344
17498
205633_s_at
211
2623526
2623527
2623529
2623530
2623532
2623535
2623537
2623538
2623539
2623540
2623542
2623543
2623545
2623546
2623547
2623551
2623552
2623553
35860
37674_at
8080184
A_23_P57877
A_24_P191588
AAH11798
AAP94018
AB063322
AK312566
ALAS1
ALAS1-201
ALAS1-202
ALAS1-204
ALAS1-205
AY260745
BAB93514
BAG35461
BC011798
CAA39794
CAA68506
CAB017498
CCDS2847
CH471055
EAW65188
EAW65189
EAW65190
ENSG00000023330
ENSP00000309259
ENSP00000378416
ENSP00000417719
ENSP00000418779
ENST00000310271
ENST00000310271.6
ENST00000394965
ENST00000394965.6
ENST00000469224
ENST00000469224.5
ENST00000484952
ENST00000484952.5
EntrezGene:211
EntrezGene:ALAS1
g4502024_3p_a_at
GE59815
GE60231
GO:0003674
GO:0003824
GO:0003870
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005759
GO:0005829
GO:0006629
GO:0006778
GO:0006782
GO:0006783
GO:0007005
GO:0008150
GO:0009058
GO:0016740
GO:0016746
GO:0019216
GO:0030170
GO:0033014
GO:0034641
GO:0042802
GO:0043167
GO:0043226
GO:0051186
HGNC:396
HPA035860
ILMN_1700047
ILMN_1728309
ILMN_2385647
IPR001917
IPR004839
IPR010961
IPR015118
IPR015421
IPR015422
IPR015424
MIM:125290
NM_000688
NM_001304443
NM_001304444
NM_199166
NP_000679
NP_001291372
NP_001291373
NP_954635
PF00155
PF09029
PH_hs_0026670
PH_hs_0031344
Q5JAM2
TC03000329.hg
UPI0000001230
X56351
XM_011533477
XM_011533478
XM_017005873
XM_024453393
XP_011531779
XP_011531780
XP_016861362
XP_024309161
Y00451
Y00451_s_at
Participant Of
output
Other forms of this molecule
PXLP-ALAS1 [mitochondrial matrix]
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
HMDB Protein
Interactors (54)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q8WTR2 DUS19      0.818 7
 UniProt:Q6P1J9 CDC73  1 0.718 8
 UniProt:Q9Y473 ZNF175  1 0.696 5
 UniProt:Q8WW24 TEKT4      0.696 5
 UniProt:Q8TBZ8 ZNF564  1 0.696 5
 UniProt:Q17RB0 RTL8B      0.696 5
 UniProt:Q17RB8 LONRF1  1 0.696 5
 UniProt:P63313 TYB10      0.696 5
 UniProt:O60437 PPL  2 0.696 5
 UniProt:Q9Y2S7 PDIP2      0.666 4
 UniProt:Q96L91 EP400  1 0.666 4
 UniProt:P13196 ALAS1  2 0.621 3
 IntAct:EBI-10198008 7120      0.556 3
 IntAct:EBI-10197995 7116      0.556 3
 UniProt:Q5W5X9 TTC23      0.556 3
 UniProt:Q15560 TCEA2      0.556 3
 UniProt:Q7Z614 SNX20      0.556 3
 UniProt:Q8TD31-3 CCHCR1      0.556 3
 UniProt:P53829 CAF40      0.556 3
 UniProt:Q6PF15 KLH35      0.556 3
 UniProt:Q9NWW7 CB042      0.556 3
 UniProt:P48837 NUP57      0.556 3
 UniProt:Q9NVN8 GNL3L      0.556 3
 UniProt:Q68DK2-5 ZFYVE26      0.556 3
 UniProt:P32902 RT04      0.556 3
 UniProt:Q6P444 MTFR2      0.556 5
 IntAct:EBI-10192162 7115      0.556 3
 UniProt:P40099  1 0.556 3
 UniProt:Q02821  2 0.556 3
 UniProt:Q0P5Q0 Q0P5Q0      0.556 3
 UniProt:Q9H788 SH24A      0.556 3
 UniProt:Q4VC05 BCL7A      0.556 3
 IntAct:EBI-10198019 84460      0.556 3
 UniProt:Q8TCT0 CERK  1 0.556 3
 UniProt:O43516 WIPF1  1 0.556 3
 UniProt:Q9Y2K6 USP20  1 0.556 3
 UniProt:Q9BVS5 TRMT61B  1 0.527 2
 UniProt:A8MXD5 GRCR1      0.488 2
 UniProt:C9JCN9 HSBPL      0.488 2
 UniProt:Q9HAQ2 KIF9  1 0.488 2
 UniProt:P08579 SNRPB2  1 0.488 2
 UniProt:O75564-2 O755642      0.488 2
 UniProt:Q4G0R1 Q4G0R1      0.488 2
 UniProt:P40123 CAP2  1 0.488 2
 IntAct:EBI-12336991 ZMAT1      0.488 2
 UniProt:Q5TAP6 UTP14C  1 0.488 2
 UniProt:A8K0Z3 WASH1      0.488 2
 UniProt:Q96CD0 FBXL8  1 0.488 2
 IntAct:EBI-18921357 TMSB4X      0.488 2
 UniProt:Q765P7 MTSS2      0.488 2
 UniProt:O75128 COBL      0.488 2
 UniProt:Q96CN5 LRC45      0.488 2
 UniProt:A0A0A0MR80 A0A0A0MR80      0.488 2
 UniProt:Q8IYW5 RNF168  2 0.488 2