FGFR3b binds to FGF

Stable Identifier
R-HSA-190263
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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In this reaction, FGF receptor in the plasma membrane binds an associating extracellular ligand, a requisite step for subsequent activation. The resulting complex consists of dimerized receptor, two ligand molecules, and heparan sulfate.

Literature References
PubMed ID Title Journal Year
16597617 Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.

Zhang, X, Ibrahimi, OA, Olsen, SK, Umemori, H, Mohammadi, M, Ornitz, DM

J Biol Chem 2006
15863029 Structural basis for fibroblast growth factor receptor activation

Mohammadi, M, Olsen, SK, Ibrahimi, OA

Cytokine Growth Factor Rev 2005
Participants
Participant Of
This event is regulated
Orthologous Events
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Reviewed
Created