FGFR4 ligand binding and activation

Stable Identifier
R-HSA-190322
Type
Pathway
Species
Homo sapiens
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FGFR4 is expressed mainly in mature skeletal muscle, and disruption of FGFR4 signaling interrupts limb muscle formation in vertebrates.

Literature References
PubMed ID Title Journal Year
7518429 Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1

Vainikka, S, Joukov, V, Wennström, S, Bergman, M, Pelicci, PG, Alitalo, K

J Biol Chem 1994
1385111 Fibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transduction

Vainikka, S, Partanen, J, Bellosta, P, Coulier, F, Birnbaum, D, Basilico, C, Jaye, M, Alitalo, K

EMBO J 1992
16597617 Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.

Zhang, X, Ibrahimi, OA, Olsen, SK, Umemori, H, Mohammadi, M, Ornitz, DM

J Biol Chem 2006
15467729 Distinct transcriptional control and action of fibroblast growth factor receptor 4 in differentiating skeletal muscle cells

Yu, S, Zheng, L, Trinh, DK, Asa, SL, Ezzat, S

Lab Invest 2004
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Orthologous Events
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