FGFR3c ligand binding and activation

Stable Identifier
R-HSA-190372
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Summation

This pathway depicts the binding of an experimentally-verified range of ligands to FGFR3c. While binding affinities may vary considerably within this set, the ligands listed have been established to bring about receptor activation at their reported physiological concentrations.

Literature References
PubMed ID Title Journal Year
16597617 Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.

Zhang, X, Ibrahimi, OA, Olsen, SK, Umemori, H, Mohammadi, M, Ornitz, DM

J Biol Chem 2006
Participants
Participant Of
Event Information
Orthologous Events
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