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Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Stable Identifier
R-HSA-190840
Type
Pathway
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Gap junction trafficking and regulation (Homo sapiens)
Gap junction trafficking (Homo sapiens)
Gap junction assembly (Homo sapiens)
Transport of connexons to the plasma membrane (Homo sapiens)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Homo sapiens)
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Through videomicroscopy, a saltatory transport of connexon vesicles along curvilinear microtubules from the Golgi to the plasma membrane has been observed (Lauf et al., 2002). Such a transport system has been described for similar secretory vesicles (Toomre et al., 1999).
Literature References
PubMed ID
Title
Journal
Year
12149451
Dynamic trafficking and delivery of connexons to the plasma membrane and accretion to gap junctions in living cells
Braconnot, S
,
Lauf, U
,
Chen, SC
,
Giepmans, BN
,
Lopez, P
,
Falk, MM
Proc Natl Acad Sci U S A
2002
Participants
Events
Budding of connexon-containing transport vesicles from the Golgi
(Homo sapiens)
Association of Golgi transport vesicles with microtubules
(Homo sapiens)
Participates
as an event of
Transport of connexons to the plasma membrane (Homo sapiens)
Orthologous Events
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Bos taurus)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Canis familiaris)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Danio rerio)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Gallus gallus)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Mus musculus)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Rattus norvegicus)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Sus scrofa)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (Xenopus tropicalis)
Authored
Gilleron, J (2007-01-03)
Segretain, D (2007-01-03)
Falk, MM (2007-01-03)
Created
Matthews, L (2007-01-09)
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