Mevalonate is phosphorylated to mevalonate-5-phosphate

Stable Identifier
R-HSA-191380
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Mevalonate kinase (MK) catalyzes the phosphorylation of mevalonate to mevalonate-5-phosphate.

Literature References
PubMed ID Title Journal Year
14730012 Mevalonate kinase is a cytosolic enzyme in humans

Hogenboom, S, Tuyp, JJ, Espeel, M, Koster, J, Wanders, RJ, Waterham, HR

J Cell Sci 2004
1377680 Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria

Schafer, BL, Bishop, RW, Kratunis, VJ, Kalinowski, SS, Mosley, ST, Gibson, KM, Tanaka, RD

J Biol Chem 1992
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
mevalonate kinase activity of MVK dimer [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created