Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate

Stable Identifier
R-HSA-191382
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cytosolic isopentenyl diphosphate isomerase (IPP isomerase) catalyzes an essential activation step in the isoprenoid biosynthetic pathway. It rearranges isopentenyl pyrophosphate into its highly electrophilic isomer, dimethylallyl pyrophosphate (DMAPP). IPP isomerase may also be located in human peroxisomes but it's function there is not clear.

Literature References
PubMed ID Title Journal Year
8806705 Human isopentenyl diphosphate: dimethylallyl diphosphate isomerase: overproduction, purification, and characterization

Hahn, FM, Xuan, JW, Chambers, AF, Poulter, CD

Arch Biochem Biophys 1996
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
isopentenyl-diphosphate delta-isomerase activity of IDI1 or 2 [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created