Mevalonate-5-phosphate is further phosphorylated.

Stable Identifier
R-HSA-191422
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Phosphomevalonate kinase (PMK) catalyzes the reversible, ATP-dependent phosphorylation of mevalonate-5-phosphate, producing mevalonate-5-pyrophosphate.

Literature References
PubMed ID Title Journal Year
16519518 Phosphomevalonate kinase: functional investigation of the recombinant human enzyme

Herdendorf, TJ, Miziorko, HM

Biochemistry 2006
14729858 Phosphomevalonate kinase is a cytosolic protein in humans

Hogenboom, S, Tuyp, JJ, Espeel, M, Koster, J, Wanders, RJ, Waterham, HR

J Lipid Res 2004
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
phosphomevalonate kinase activity of PMVK [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created