Reactome | TUBA1B [cytosol]

TUBA1B [cytosol]

Stable Identifier

R-HSA-191691

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Tubulin K-alpha-1, alpha K tubulin-1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P68363 TUBA1B

Gene Names

TUBA1B

Chain

chain:1-451, chain:1-450

Reference Genes

BioGPS Gene:10376 TUBA1B

COSMIC (genes):TUBA1B TUBA1B

CTD Gene:10376 TUBA1B

dbSNP Gene:10376 TUBA1B

ENSEMBL:ENSG00000123416 TUBA1B

HGNC:18809 TUBA1B

KEGG:hsa:10376 TUBA1B

Monarch:10376 TUBA1B

NCBI Gene:10376 TUBA1B

OMIM:602530 TUBA1B

UCSC:P68363 TUBA1B

Reference Transcript

RefSeq:NM_006082.2 TUBA1B

Other Identifiers

10376

11744345_x_at

11756979_x_at

16764285

201090_PM_x_at

201090_x_at

209251_PM_x_at

211058_PM_x_at

211058_x_at

211072_PM_x_at

211072_x_at

211750_PM_x_at

212639_PM_x_at

212639_x_at

213646_PM_x_at

213646_x_at

2872626

32272_at

3344233

3344241

3344242

3413815

3413819

3413821

3413822

3413824

3453738

3453739

3453740

3453741

3453742

3453743

3453744

3453745

3453746

3453747

3453748

3453749

3453750

3453751

3453752

3453753

3453754

3453841

3453845

3453846

3640627

59760_f_at

7963046

GO:0000226

GO:0000278

GO:0003723

GO:0003725

GO:0003824

GO:0003924

GO:0005198

GO:0005200

GO:0005515

GO:0005525

GO:0005737

GO:0005856

GO:0005874

GO:0005881

GO:0007010

GO:0007017

GO:0015630

GO:0016787

GO:0030705

GO:0031625

GO:0043226

GO:0051301

GO:0071353

HMNXSV003034622

Hs.240615.2.S1_3p_x_at

Hs.272897.2.S1_3p_x_at

ILMN_1742167

ILMN_1800261

PH_hs_0040665

TC12000363.hg

TC12001470.hg

TC12002866.hg

g13623540_3p_x_at

g5174476_3p_x_at

Participates

as a candidate of

Other forms of this molecule

TUBA1B [axonemal microtubule]

TUBA1B(1-450) [cytosol]

Polyglutamyl-TUBA1B [cytosol]

L-isoglutamyl polyglycyl-TUBA1B [cytosol]

TUBA1B unfolded [cytosol]

TUBA1B folding intermediate [cytosol]

Ac K40 TUBA1B [axonemal microtubule]

AcK-TUBA1B [cytosol]

Inferred To

TUBA1A [cytosol] (Dictyostelium discoideum)

TUBA1A [cytosol] (Plasmodium falciparum)

TUBA1A [cytosol] (Saccharomyces cerevisiae)

TUBA1A [cytosol] (Schizosaccharomyces pombe)

tuba2 [cytosol] (Danio rerio)

Homologues of TUBA1A [cytosol] (Dictyostelium discoideum)

Homologues of TUBA1A [cytosol] (Plasmodium falciparum)

Tubulin alpha-1B chain [cytosol] (Mus musculus)

Tubulin alpha-1B chain [cytosol] (Rattus norvegicus)

TUBA1B [cytosol] (Canis familiaris)

TUBA1B [cytosol] (Gallus gallus)

TUBA1B [cytosol] (Saccharomyces cerevisiae)

TUBA1B [cytosol] (Schizosaccharomyces pombe)

TUBA1B [cytosol] (Sus scrofa)

Homologues of TUBA1B [cytosol] (Saccharomyces cerevisiae)

Homologues of TUBA1B [cytosol] (Schizosaccharomyces pombe)

tuba1b [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_006073.2

OpenTargets

ENSG00000123416

ENSEMBL

ENSP00000336799, ENST00000336023

HPA

ENSG00000123416-TUBA1B

PRO

P68363

Pharos - Targets

P68363

GlyGen

P68363

HMDB Protein

HMDBP08594

PDB

7LXB, 7M18, 6QVE, 8VRK, 5IJ0, 8VRJ, 6QVJ, 9BP6, 5N5N, 7SJ7, 6QUS, 7SJA, 7SJ9, 6J8O, 6I2I, 7SJ8, 7Z6S, 5IJ9, 6S8L, 6J4V, 6QUY, 7PJF, 8VA2, 8VT7, 6E7B, 6E7C, 7ZCW, 7M20, 2E4H

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P17987 TCP1	1	TCP1 [cytosol] (R-HSA-390448)	0.643	4
UniProt:Q15398 DLGAP5	1	DLGAP5 [cytosol] (R-HSA-264452)	0.643	3
UniProt:P37840 SNCA	5	SNCA [cytosol] (R-HSA-5658500) p-S129-SNCA [cytosol] (R-HSA-9836432) Ub-SNCA [cytosol] (R-HSA-5660754) SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569)	0.556	3
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.556	3
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.527	3
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	2

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