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SNRPE [cytosol]
Stable Identifier
R-HSA-191782
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Sm protein E, snRNP E, RUXE_HUMAN, Small nuclear ribonucleoprotein E, snRNP-E, Sm-E, SmE
Locations in the PathwayBrowser for interactor UniProt:Q15029 EFTUD2
Expand all
Metabolism of RNA (Homo sapiens)
Metabolism of non-coding RNA (Homo sapiens)
snRNP Assembly (Homo sapiens)
Loading and methylation of Sm proteins onto SMN Complexes (Homo sapiens)
SNRPE [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62304 SNRPE
Gene Names
SNRPE
Chain
chain:1-92
Reference Genes
BioGPS Gene:6635 SNRPE
COSMIC (genes):SNRPE SNRPE
CTD Gene:6635 SNRPE
dbSNP Gene:6635 SNRPE
ENSEMBL:ENSG00000182004 SNRPE
ENSEMBL_homo_sapiens_GENE:ENSG00000182004.13 SNRPE
HGNC:11161 SNRPE
KEGG Gene (Homo sapiens):6635 SNRPE
Monarch:6635 SNRPE
NCBI Gene:6635 SNRPE
OMIM:128260 SNRPE
UCSC:P62304 SNRPE
Reference Transcript
RefSeq:NM_001328638.1 SNRPE
RefSeq:NM_001304464.1 SNRPE
RefSeq:NM_003094.3 SNRPE
RefSeq:NM_001328637.1 SNRPE
Other Identifiers
11718040_x_at
11718041_at
203316_PM_s_at
203316_s_at
231112_PM_at
231112_at
2375878
2375879
2375884
2375886
2375888
2375889
2375890
2375891
2375892
2375894
2978642
3198044
3847247
3847251
38678_at
38679_g_at
6635
7908988
8160033
82273_at
A_23_P126291
A_33_P3244424
GE87544
GO:0000245
GO:0000387
GO:0000398
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005682
GO:0005683
GO:0005684
GO:0005685
GO:0005686
GO:0005687
GO:0005689
GO:0005697
GO:0005737
GO:0005829
GO:0006397
GO:0008380
GO:0016071
GO:0030532
GO:0034709
GO:0034715
GO:0034719
GO:0036261
GO:0043226
GO:0043229
GO:0046540
GO:0065003
GO:0071005
GO:0071007
GO:0071011
GO:0071013
GO:1903241
GO:1990904
HMNXSV003030680
Hs.1066.1.A1_3p_at
ILMN_1656424
ILMN_2046199
M21259_at
PH_hs_0029773
PH_hs_0038261
TC01001693.hg
TC19001078.hg
g4507128_3p_a_at
g4507128_3p_x_at
Participates
as an input of
Loading and methylation of Sm proteins onto SMN Complexes (Homo sapiens)
as a component of
snRNP Sm core complex [cytosol] (Homo sapiens)
Other forms of this molecule
SNRPE [nucleoplasm]
Inferred To
snrpe [cytosol]
(Danio rerio)
snr-6 [cytosol]
(Caenorhabditis elegans)
Homologues of SNRPE [cytosol]
(Bos taurus)
SNRPE [cytosol]
(Bos taurus)
SNRPE [cytosol]
(Canis familiaris)
SNRPE [cytosol]
(Gallus gallus)
SNRPE [cytosol]
(Plasmodium falciparum)
SNRPE [cytosol]
(Sus scrofa)
Ghost homologue of SNRPE [cytosol]
(Xenopus tropicalis)
SME1 [cytosol]
(Saccharomyces cerevisiae)
SmE [cytosol]
(Drosophila melanogaster)
snrpE [cytosol]
(Dictyostelium discoideum)
sme1 [cytosol]
(Schizosaccharomyces pombe)
Snrpe [cytosol]
(Mus musculus)
Snrpe [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_001315566.1
,
NP_001291393.1
,
NP_001315567.1
,
NP_003085.1
OpenTargets
ENSG00000182004
HPA
ENSG00000182004-SNRPE
GeneCards
P62304
Ensembl
ENSP00000400591
,
ENSG00000182004
,
ENST00000414487
PRO
P62304
Pharos - Targets
P62304
Orphanet
21748
PDB
8CH6
,
5Z57
,
5YZG
,
8RC0
,
6V4X
,
5XJS
,
7ABG
,
6Y53
,
5XJT
,
7EVO
,
6QW6
,
4F7U
,
8Q7Q
,
8C6J
,
5XJC
,
6QDV
,
5O9Z
,
3JCR
,
7W5A
,
6ID0
,
7B0Y
,
7A5P
,
6ID1
,
6Y5Q
,
5Z56
,
7W5B
,
8Q7V
,
6QX9
,
3PGW
,
5XJQ
,
5Z58
,
8QO9
,
8Y7E
,
7ABI
,
7DVQ
,
5XJR
,
8Q91
,
5XJU
,
6AH0
,
4V98
,
8HK1
,
8Y6O
,
7QTT
,
7W59
,
6FF7
,
5MQF
,
3CW1
,
8Q7W
,
6ICZ
,
4WZJ
,
4PJO
,
5XJL
,
7VPX
,
8Q7X
Interactors (85)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62306 SNRPF
2
SNRPF [nucleoplasm]
(R-HSA-71907)
SNRPF [cytosol]
(R-HSA-191852)
0.93
14
UniProt:P62308 SNRPG
2
SNRPG [nucleoplasm]
(R-HSA-71909)
SNRPG [cytosol]
(R-HSA-191827)
0.869
11
UniProt:P14678 SNRPB
4
SNRPB [nucleoplasm]
(R-HSA-71896)
Me2-R108,R112-SNRPB [nucleoplasm]
(R-HSA-192213)
SNRPB [cytosol]
(R-HSA-191798)
2xMe-SNRPB [cytosol]
(R-HSA-192218)
0.793
7
UniProt:P54105 CLNS1A
1
CLNS1A [cytosol]
(R-HSA-191796)
0.773
8
UniProt:Q9Y333 LSM2
2
LSM2 [nucleoplasm]
(R-HSA-71894)
LSM2 [cytosol]
(R-HSA-429849)
0.745
5
UniProt:P62316 SNRPD2
2
SNRPD2 [nucleoplasm]
(R-HSA-71901)
SNRPD2 [cytosol]
(R-HSA-191810)
0.744
6
UniProt:Q9Y4Y9 LSM5
2
LSM5 [cytosol]
(R-HSA-429839)
LSM5 [nucleoplasm]
(R-HSA-6806795)
0.743
5
UniProt:Q8TEQ6 GEMIN5
2
GEMIN5 [cytosol]
(R-HSA-191833)
GEMIN5 [nucleoplasm]
(R-HSA-191765)
0.708
6
UniProt:O14893 GEMIN2
2
GEMIN2 [nucleoplasm]
(R-HSA-191795)
GEMIN2 [cytosol]
(R-HSA-191835)
0.708
7
UniProt:Q8WXD5 GEMIN6
2
GEMIN6 [nucleoplasm]
(R-HSA-191799)
GEMIN6 [cytosol]
(R-HSA-191771)
0.688
5
UniProt:Q15428 SF3A2
1
SF3A2 [nucleoplasm]
(R-HSA-71964)
0.669
5
UniProt:P62314 SNRPD1
3
2xMe-SNRPD1 [nucleoplasm]
(R-HSA-192215)
SNRPD1 [cytosol]
(R-HSA-191890)
2xMe-SNRPD1 [cytosol]
(R-HSA-192217)
0.669
5
UniProt:O60306 AQR
1
AQR [nucleoplasm]
(R-HSA-6781960)
0.648
5
UniProt:O75533 SF3B1
1
SF3B1 [nucleoplasm]
(R-HSA-71968)
0.643
5
UniProt:P08579 SNRPB2
1
SNRPB2 [nucleoplasm]
(R-HSA-71960)
0.643
5
UniProt:P08621 SNRNP70
1
SNRNP70 [nucleoplasm]
(R-HSA-71913)
0.643
7
UniProt:P09012 SNRPA
1
SNRPA [nucleoplasm]
(R-HSA-71915)
0.643
5
UniProt:Q99459 CDC5L
1
CDC5L [nucleoplasm]
(R-HSA-5420887)
0.643
5
UniProt:O95400 CD2BP2
1
CD2BP2 [nucleoplasm]
(R-HSA-72054)
0.643
5
UniProt:Q15459 SF3A1
1
SF3A1 [nucleoplasm]
(R-HSA-71962)
0.643
5
UniProt:Q9Y3B4 SF3B6
1
SF3B6 [nucleoplasm]
(R-HSA-83808)
0.643
4
UniProt:Q16637 SMN1
2
SMN1 [nucleoplasm]
(R-HSA-191892)
SMN1 [cytosol]
(R-HSA-191839)
0.643
5
UniProt:Q15029 EFTUD2
1
EFTUD2 [nucleoplasm]
(R-HSA-71883)
0.643
5
UniProt:O95149 SNUPN
1
SNUPN [cytosol]
(R-HSA-191857)
0.643
5
UniProt:P14678-2 SNRPB
0.623
3
UniProt:Q9Y4Z0 LSM4
2
LSM4 [nucleoplasm]
(R-HSA-6806804)
LSM4 [cytosol]
(R-HSA-429956)
0.547
2
UniProt:P62310 LSM3
2
LSM3 [nucleoplasm]
(R-HSA-6806807)
LSM3 [cytosol]
(R-HSA-429894)
0.547
2
UniProt:P83369 LSM11
1
LSM11 [nucleoplasm]
(R-HSA-110760)
0.527
4
UniProt:P09234 SNRPC
1
SNRPC [nucleoplasm]
(R-HSA-8865876)
0.527
3
UniProt:P57678 GEMIN4
2
GEMIN4 [nucleoplasm]
(R-HSA-191841)
GEMIN4 [cytosol]
(R-HSA-191836)
0.527
4
UniProt:Q96LT9 RNPC3
1
RNPC3 [nucleoplasm]
(R-HSA-6787844)
0.527
4
UniProt:Q9BWJ5 SF3B5
1
SF3B5 [nucleoplasm]
(R-HSA-71979)
0.527
2
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.527
4
UniProt:Q7L014 DDX46
1
DDX46 [nucleoplasm]
(R-HSA-5688096)
0.527
2
UniProt:Q96DI7 SNRNP40
1
SNRNP40 [nucleoplasm]
(R-HSA-71877)
0.527
4
UniProt:Q7L2J0 MEPCE
0.527
4
UniProt:Q9UHI6 DDX20
2
DDX20 [nucleoplasm]
(R-HSA-191847)
DDX20 [cytosol]
(R-HSA-191838)
0.527
4
UniProt:Q86UT8 CATAC
0.527
3
UniProt:A8MWD9 RUXGL
0.527
2
UniProt:Q6IEG0 SNRNP48
1
SNRNP48 [nucleoplasm]
(R-HSA-6787849)
0.527
4
UniProt:Q96DF8 ESS2
0.527
2
UniProt:Q15020 SART3
0.527
4
UniProt:Q9BWU0 NADAP
0.527
4
UniProt:Q9UDW3 ZMAT5
1
ZMAT5 [nucleoplasm]
(R-HSA-6787850)
0.527
2
UniProt:O95926 SYF2
1
SYF2 [nucleoplasm]
(R-HSA-8867884)
0.527
4
UniProt:Q96NB3 ZNF830
1
ZNF830 [nucleoplasm]
(R-HSA-6781962)
0.527
2
UniProt:Q13435 SF3B2
1
SF3B2 [nucleoplasm]
(R-HSA-71971)
0.527
4
UniProt:Q6P2Q9 PRPF8
1
PRPF8 [nucleoplasm]
(R-HSA-83810)
0.527
4
UniProt:Q9H6E5 STPAP
0.527
4
UniProt:Q8N954 GPT11
0.527
3
UniProt:O43395 PRPF3
1
PRPF3 [nucleoplasm]
(R-HSA-6806806)
0.527
4
UniProt:Q8IYT2 CMTR2
0.527
3
UniProt:Q8IWX8 CHERP
1
CHERP [nucleoplasm]
(R-HSA-8865901)
0.527
3
UniProt:Q9HCS7 XAB2
1
XAB2 [nucleoplasm]
(R-HSA-67411)
0.527
4
UniProt:Q15393 SF3B3
1
SF3B3 [nucleoplasm]
(R-HSA-71973)
0.527
3
UniProt:P62312 LSM6
2
LSM6 [cytosol]
(R-HSA-429936)
LSM6 [nucleoplasm]
(R-HSA-6806794)
0.527
2
UniProt:P09661 SNRPA1
1
SNRPA1 [nucleoplasm]
(R-HSA-71958)
0.527
4
UniProt:Q9Y5B6 PAXB1
0.527
4
UniProt:Q8N8D1 PDCD7
1
PDCD7 [nucleoplasm]
(R-HSA-6787851)
0.527
4
UniProt:Q96RS0 TGS1
2
TGS1 [cytosol]
(R-HSA-192209)
TGS1 [nucleoplasm]
(R-HSA-400176)
0.527
4
UniProt:P35637 FUS
1
FUS [nucleoplasm]
(R-HSA-72040)
0.527
2
UniProt:Q96GM8 TOE1
0.527
4
UniProt:Q9NWZ8 GEMIN8
2
GEMIN8 [nucleoplasm]
(R-HSA-8932892)
GEMIN8 [cytosol]
(R-HSA-8932878)
0.527
4
UniProt:O75643 SNRNP200
1
SNRNP200 [nucleoplasm]
(R-HSA-71885)
0.527
4
UniProt:Q9BRX9 WDR83
1
WDR83 [endosome membrane]
(R-HSA-5672942)
0.527
4
UniProt:P63162 SNRPN
1
Me2-R108,R112-SNRPN [nucleoplasm]
(R-HSA-8865931)
0.527
4
UniProt:Q56P03 EAPP
0.527
4
UniProt:O94906 PRPF6
1
PRPF6 [nucleoplasm]
(R-HSA-71881)
0.527
4
UniProt:Q12874 SF3A3
1
SF3A3 [nucleoplasm]
(R-HSA-71966)
0.527
4
UniProt:Q15427 SF3B4
1
SF3B4 [nucleoplasm]
(R-HSA-71975)
0.527
4
UniProt:Q2TBE0 CWF19L2
1
CWF19L2 [nucleoplasm]
(R-HSA-9770846)
0.527
4
UniProt:Q8WVK2 SNRNP27
1
SNRNP27 [nucleoplasm]
(R-HSA-6806778)
0.527
4
UniProt:Q15696 ZRSR2
1
ZRSR2 [nucleoplasm]
(R-HSA-8865914)
0.527
3
UniProt:Q9BUQ8 DDX23
1
DDX23 [nucleoplasm]
(R-HSA-71879)
0.527
4
UniProt:Q9H875 PRKRIP1
1
PRKRIP1 [nucleoplasm]
(R-HSA-9769594)
0.527
2
UniProt:P62318 SNRPD3
3
SNRPD3 [nucleoplasm]
(R-HSA-71903)
2xMe-SNRPD3 [nucleoplasm]
(R-HSA-192219)
2xMe-SNRPD3 [cytosol]
(R-HSA-191781)
0.527
4
UniProt:Q9H5Z1 DHX35
1
DHX35 [nucleoplasm]
(R-HSA-9770427)
0.527
4
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.527
4
UniProt:P16383 GCFC2
1
GCFC2 [nucleoplasm]
(R-HSA-8869311)
0.527
2
UniProt:O14744 PRMT5
3
p-Y297,304,307-PRMT5 [nucleoplasm]
(R-HSA-5211300)
PRMT5 [nucleoplasm]
(R-HSA-5205609)
PRMT5 [cytosol]
(R-HSA-191876)
0.527
2
UniProt:O43719 HTATSF1
1
HTATSF1 [nucleoplasm]
(R-HSA-9770246)
0.527
4
UniProt:Q8WUD4 CCDC12
1
CCDC12 [nucleoplasm]
(R-HSA-9769561)
0.527
4
UniProt:Q9BRR8 GPATCH1
1
GPATCH1 [nucleoplasm]
(R-HSA-9770419)
0.527
4
UniProt:O43290 SART1
1
SART1 [nucleoplasm]
(R-HSA-4615999)
0.527
4
UniProt:O60508 CDC40
1
CDC40 [nucleoplasm]
(R-HSA-72062)
0.527
4
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