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SNRPB [cytosol]
Stable Identifier
R-HSA-191798
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Sm Protein B, Small nuclear ribonucleoprotein associated proteins B and B', snRNP-B, Sm protein B/B', Sm-B/Sm-B', SmB/SmB'
Locations in the PathwayBrowser for interactor UniProt:Q15029 EFTUD2
Expand all
Metabolism of RNA (Homo sapiens)
Metabolism of non-coding RNA (Homo sapiens)
snRNP Assembly (Homo sapiens)
Loading and methylation of Sm proteins onto SMN Complexes (Homo sapiens)
SNRPB [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P14678 SNRPB
Gene Names
SNRPB, COD, SNRPB1
Chain
chain:1-240
Reference Genes
BioGPS Gene:6628 SNRPB
COSMIC (genes):SNRPB SNRPB
CTD Gene:6628 SNRPB
dbSNP Gene:6628 SNRPB
ENSEMBL:ENSG00000125835 SNRPB
ENSEMBL_homo_sapiens_GENE:ENSG00000125835.20 SNRPB
HGNC:11153 SNRPB
KEGG Gene (Homo sapiens):6628 SNRPB
Monarch:6628 SNRPB
NCBI Gene:6628 SNRPB
OMIM:182282 SNRPB
UCSC:P14678 SNRPB
Reference Transcript
RefSeq:NM_003091.3 SNRPB
RefSeq:NM_198216.1 SNRPB
Other Identifiers
11720935_a_at
11736675_a_at
11754105_x_at
11757344_x_at
11757660_a_at
11757661_x_at
11760170_x_at
16916546
208821_PM_at
208821_at
213175_PM_s_at
213175_s_at
38455_at
38456_s_at
3894999
3895000
3895001
3895002
3895004
3895005
3895006
3895011
3895017
3895020
3895021
6628
8064502
A_23_P154675
GE81233
GE85808
GO:0000387
GO:0000398
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005682
GO:0005683
GO:0005684
GO:0005685
GO:0005686
GO:0005687
GO:0005689
GO:0005697
GO:0005737
GO:0005829
GO:0006397
GO:0006479
GO:0008380
GO:0016071
GO:0030532
GO:0034709
GO:0034719
GO:0036211
GO:0036261
GO:0043226
GO:0046540
GO:0065003
GO:0070034
GO:0071004
GO:0071005
GO:0071007
GO:0071013
GO:0071204
GO:0071208
GO:1903241
GO:1990446
GO:1990447
GO:1990904
HMNXSV003058451
Hs.83753.1.S1_3p_s_at
ILMN_1774661
ILMN_1799103
PH_hs_0029017
PH_hs_0035482
TC20001744.hg
X17567_s_at
X52979_rna1_s_at
g190246_3p_at
Participates
as an input of
Loading and methylation of Sm proteins onto SMN Complexes (Homo sapiens)
Other forms of this molecule
SNRPB [nucleoplasm]
Me2-R108,R112-SNRPB [nucleoplasm]
2xMe-SNRPB [cytosol]
Inferred To
SmB [cytosol]
(Drosophila melanogaster)
SMB1 [cytosol]
(Saccharomyces cerevisiae)
snr-2 [cytosol]
(Caenorhabditis elegans)
Homologues of SNRPB [cytosol]
(Bos taurus)
SNRPN [cytosol]
(Bos taurus)
SNRPN [cytosol]
(Sus scrofa)
snrpb [cytosol]
(Danio rerio)
snrpb [cytosol]
(Dictyostelium discoideum)
snrpb [cytosol]
(Xenopus tropicalis)
SNRPB [cytosol]
(Bos taurus)
SNRPB [cytosol]
(Canis familiaris)
SNRPB [cytosol]
(Gallus gallus)
SNRPB [cytosol]
(Plasmodium falciparum)
Snrpb [cytosol]
(Mus musculus)
Snrpb [cytosol]
(Rattus norvegicus)
smb1 [cytosol]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_937859.1
,
NP_003082.1
OpenTargets
ENSG00000125835
GeneCards
P14678
HPA
ENSG00000125835-SNRPB
Ensembl
ENSG00000125835
,
ENST00000381342
,
ENST00000438552
,
ENSP00000412566
,
ENSP00000370746
PRO
P14678
Pharos - Targets
P14678
Orphanet
23011
PDB
4PJO
,
7W59
,
6AH0
,
3JCR
,
3CW1
,
8Q7Q
,
8C6J
,
7QTT
,
5MQF
,
8HK1
,
4WZJ
,
7W5A
,
6QDV
,
8Y6O
,
7DVQ
,
7ABG
,
7EVO
,
6V4X
,
6FF7
,
7ABI
,
6Y53
,
8RC0
,
3PGW
,
8Q91
,
6QW6
,
5Z56
,
7A5P
,
6ICZ
,
6ID1
,
8CH6
,
6QX9
,
8Y7E
,
6ID0
,
8QO9
,
8Q7V
,
1D3B
,
7W5B
,
5XJC
,
5Z58
,
6Y5Q
,
5O9Z
,
8Q7W
,
5YZG
,
5Z57
,
7VPX
,
8Q7X
Interactors (77)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95400 CD2BP2
1
CD2BP2 [nucleoplasm]
(R-HSA-72054)
0.882
11
UniProt:P62318 SNRPD3
3
SNRPD3 [nucleoplasm]
(R-HSA-71903)
2xMe-SNRPD3 [nucleoplasm]
(R-HSA-192219)
2xMe-SNRPD3 [cytosol]
(R-HSA-191781)
0.88
8
UniProt:Q16637 SMN1
2
SMN1 [nucleoplasm]
(R-HSA-191892)
SMN1 [cytosol]
(R-HSA-191839)
0.801
6
UniProt:P57678 GEMIN4
2
GEMIN4 [nucleoplasm]
(R-HSA-191841)
GEMIN4 [cytosol]
(R-HSA-191836)
0.8
5
UniProt:P62316 SNRPD2
2
SNRPD2 [nucleoplasm]
(R-HSA-71901)
SNRPD2 [cytosol]
(R-HSA-191810)
0.793
7
UniProt:P62304 SNRPE
2
SNRPE [nucleoplasm]
(R-HSA-71905)
SNRPE [cytosol]
(R-HSA-191782)
0.793
7
UniProt:P62314 SNRPD1
3
2xMe-SNRPD1 [nucleoplasm]
(R-HSA-192215)
SNRPD1 [cytosol]
(R-HSA-191890)
2xMe-SNRPD1 [cytosol]
(R-HSA-192217)
0.793
5
UniProt:P62306 SNRPF
2
SNRPF [nucleoplasm]
(R-HSA-71907)
SNRPF [cytosol]
(R-HSA-191852)
0.793
7
UniProt:P08621 SNRNP70
1
SNRNP70 [nucleoplasm]
(R-HSA-71913)
0.784
8
UniProt:P54105 CLNS1A
1
CLNS1A [cytosol]
(R-HSA-191796)
0.768
7
UniProt:P62308 SNRPG
2
SNRPG [nucleoplasm]
(R-HSA-71909)
SNRPG [cytosol]
(R-HSA-191827)
0.734
5
UniProt:Q8WWY3 PRPF31
1
PRPF31 [nucleoplasm]
(R-HSA-6806772)
0.725
5
UniProt:P09234 SNRPC
1
SNRPC [nucleoplasm]
(R-HSA-8865876)
0.723
6
UniProt:Q15020 SART3
0.669
4
UniProt:O75643 SNRNP200
1
SNRNP200 [nucleoplasm]
(R-HSA-71885)
0.669
4
UniProt:Q15428 SF3A2
1
SF3A2 [nucleoplasm]
(R-HSA-71964)
0.669
3
UniProt:O94906 PRPF6
1
PRPF6 [nucleoplasm]
(R-HSA-71881)
0.669
4
UniProt:Q15029 EFTUD2
1
EFTUD2 [nucleoplasm]
(R-HSA-71883)
0.669
3
UniProt:O14744 PRMT5
3
p-Y297,304,307-PRMT5 [nucleoplasm]
(R-HSA-5211300)
PRMT5 [nucleoplasm]
(R-HSA-5205609)
PRMT5 [cytosol]
(R-HSA-191876)
0.669
4
UniProt:O43719 HTATSF1
1
HTATSF1 [nucleoplasm]
(R-HSA-9770246)
0.669
4
UniProt:O60306 AQR
1
AQR [nucleoplasm]
(R-HSA-6781960)
0.648
4
UniProt:Q8TEQ6 GEMIN5
2
GEMIN5 [cytosol]
(R-HSA-191833)
GEMIN5 [nucleoplasm]
(R-HSA-191765)
0.643
4
UniProt:Q9Y3F4 STRAP
1
STRAP [cytosol]
(R-HSA-2127556)
0.59
2
UniProt:P38432 COIL
0.564
2
UniProt:P54253 ATX1
0.556
3
UniProt:O95777 LSM8
1
LSM8 [nucleoplasm]
(R-HSA-6806779)
0.547
2
UniProt:Q9Y333 LSM2
2
LSM2 [nucleoplasm]
(R-HSA-71894)
LSM2 [cytosol]
(R-HSA-429849)
0.547
2
UniProt:Q96LT9 RNPC3
1
RNPC3 [nucleoplasm]
(R-HSA-6787844)
0.527
2
UniProt:P38919 EIF4A3
2
EIF4A3 [nucleoplasm]
(R-HSA-8849149)
EIF4A3 [cytosol]
(R-HSA-927868)
0.527
2
UniProt:O75533 SF3B1
1
SF3B1 [nucleoplasm]
(R-HSA-71968)
0.527
4
UniProt:O14893 GEMIN2
2
GEMIN2 [nucleoplasm]
(R-HSA-191795)
GEMIN2 [cytosol]
(R-HSA-191835)
0.527
2
UniProt:P08579 SNRPB2
1
SNRPB2 [nucleoplasm]
(R-HSA-71960)
0.527
5
UniProt:Q9BWJ5 SF3B5
1
SF3B5 [nucleoplasm]
(R-HSA-71979)
0.527
2
UniProt:O43172 PRPF4
1
PRPF4 [nucleoplasm]
(R-HSA-71890)
0.527
3
UniProt:Q09161 NCBP1
2
NCBP1 [nucleoplasm]
(R-HSA-51469)
NCBP1 [cytosol]
(R-HSA-162459)
0.527
4
UniProt:P61326 MAGOH
1
MAGOH [nucleoplasm]
(R-HSA-156658)
0.527
2
UniProt:Q96DI7 SNRNP40
1
SNRNP40 [nucleoplasm]
(R-HSA-71877)
0.527
3
UniProt:Q9UHI6 DDX20
2
DDX20 [nucleoplasm]
(R-HSA-191847)
DDX20 [cytosol]
(R-HSA-191838)
0.527
2
UniProt:Q9Y2J2 EPB41L3
1
EPB41L3 [cytosol]
(R-HSA-6797563)
0.527
2
UniProt:P09012 SNRPA
1
SNRPA [nucleoplasm]
(R-HSA-71915)
0.527
3
UniProt:Q6IEG0 SNRNP48
1
SNRNP48 [nucleoplasm]
(R-HSA-6787849)
0.527
2
UniProt:Q9BWU0 NADAP
0.527
3
UniProt:Q86VM9 ZCH18
0.527
2
UniProt:Q8WXD5 GEMIN6
2
GEMIN6 [nucleoplasm]
(R-HSA-191799)
GEMIN6 [cytosol]
(R-HSA-191771)
0.527
2
UniProt:Q9UJV9 DDX41
4
DDX41 [nucleoplasm]
(R-HSA-9769601)
DDX41 [cytosol]
(R-HSA-3134807)
K48polyUb-DDX41 [cytosol]
(R-HSA-3134942)
K48polyUb-DDX41 [cytosol]
(R-HSA-3134941)
0.527
2
UniProt:Q9BZJ0 CRNKL1
1
CRNKL1 [nucleoplasm]
(R-HSA-8867899)
0.527
2
UniProt:Q13435 SF3B2
1
SF3B2 [nucleoplasm]
(R-HSA-71971)
0.527
3
UniProt:Q6P2Q9 PRPF8
1
PRPF8 [nucleoplasm]
(R-HSA-83810)
0.527
3
UniProt:Q15459 SF3A1
1
SF3A1 [nucleoplasm]
(R-HSA-71962)
0.527
3
UniProt:Q8N954 GPT11
0.527
2
UniProt:Q8IYT2 CMTR2
0.527
3
UniProt:Q9HCS7 XAB2
1
XAB2 [nucleoplasm]
(R-HSA-67411)
0.527
3
UniProt:O43395 PRPF3
1
PRPF3 [nucleoplasm]
(R-HSA-6806806)
0.527
4
UniProt:Q15393 SF3B3
1
SF3B3 [nucleoplasm]
(R-HSA-71973)
0.527
2
UniProt:P62312 LSM6
2
LSM6 [cytosol]
(R-HSA-429936)
LSM6 [nucleoplasm]
(R-HSA-6806794)
0.527
2
UniProt:P09661 SNRPA1
1
SNRPA1 [nucleoplasm]
(R-HSA-71958)
0.527
4
UniProt:Q9Y5B6 PAXB1
0.527
2
UniProt:P83876 TXNL4A
1
TXNL4A [nucleoplasm]
(R-HSA-71875)
0.527
2
UniProt:Q96RS0 TGS1
2
TGS1 [cytosol]
(R-HSA-192209)
TGS1 [nucleoplasm]
(R-HSA-400176)
0.527
2
UniProt:Q96GM8 TOE1
0.527
3
UniProt:Q9NWZ8 GEMIN8
2
GEMIN8 [nucleoplasm]
(R-HSA-8932892)
GEMIN8 [cytosol]
(R-HSA-8932878)
0.527
3
UniProt:Q56P03 EAPP
0.527
3
UniProt:Q9UK45 LSM7
2
LSM7 [nucleoplasm]
(R-HSA-6806802)
LSM7 [cytosol]
(R-HSA-2028610)
0.527
2
UniProt:Q9Y312 AAR2
0.527
2
UniProt:Q15427 SF3B4
1
SF3B4 [nucleoplasm]
(R-HSA-71975)
0.527
3
UniProt:Q12874 SF3A3
1
SF3A3 [nucleoplasm]
(R-HSA-71966)
0.527
2
UniProt:Q8TBF4 ZCRB1
2
ZCRB1 [cytosol]
(R-HSA-9682010)
ZCRB1 [nucleoplasm]
(R-HSA-6787853)
0.527
2
UniProt:P52298 NCBP2
2
NCBP2 [nucleoplasm]
(R-HSA-51463)
NCBP2 [cytosol]
(R-HSA-162458)
0.527
2
UniProt:Q9NQ92 COPRS
1
COPRS [nucleoplasm]
(R-HSA-5212681)
0.527
2
UniProt:Q13523 PRPF4B
1
PRPF4B [nucleoplasm]
(R-HSA-9769525)
0.527
2
UniProt:Q15696 ZRSR2
1
ZRSR2 [nucleoplasm]
(R-HSA-8865914)
0.527
2
UniProt:Q9BUQ8 DDX23
1
DDX23 [nucleoplasm]
(R-HSA-71879)
0.527
3
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.527
2
UniProt:Q9BRS2 RIOK1
2
RIOK1 [nucleoplasm]
(R-HSA-5226890)
RIOK1 [cytosol]
(R-HSA-6791525)
0.527
3
UniProt:O43290 SART1
1
SART1 [nucleoplasm]
(R-HSA-4615999)
0.527
2
UniProt:Q9BQA1 WDR77
3
WDR77 [nucleoplasm]
(R-HSA-5205610)
pT5-WDR77 [nucleoplasm]
(R-HSA-5205602)
WDR77 [cytosol]
(R-HSA-191823)
0.527
3
UniProt:O60508 CDC40
1
CDC40 [nucleoplasm]
(R-HSA-72062)
0.527
2
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