Reactome | 25(R) DHCA-CoA is translocated from the cytosol to the peroxisome

25(R) DHCA-CoA is translocated from the cytosol to the peroxisome

Stable Identifier

R-HSA-193482

Type

Reaction [transition]

Species

Homo sapiens

Compartment

peroxisomal membrane

Synonyms

25(R) DHCA-CoA [ cytosol] => 25(R) DHCA-CoA [peroxisome]

ReviewStatus

5/5

Locations in the PathwayBrowser

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Metabolism (Homo sapiens)

- Metabolism of lipids (Homo sapiens)
  - Metabolism of steroids (Homo sapiens)
    - Bile acid and bile salt metabolism (Homo sapiens)
      - Synthesis of bile acids and bile salts (Homo sapiens)
        
        Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)
        
        25(R) DHCA-CoA is translocated from the cytosol to the peroxisome (Homo sapiens)

General

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25(R) DHCA-CoA is translocated from the cytosol to the peroxisome

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25(R) DHCA-CoA is transported from the cytosol into the peroxisome. Indirect evidence suggests that a member of the ABC class of transporters mediates this reaction.

Literature References

PubMed ID	Title	Journal	Year
12543708	The enzymes, regulation, and genetics of bile acid synthesis Russell, DW	Annu Rev Biochem	2003

Participants

Input

25(R) DHCA-CoA [cytosol]

Output

25(R) DHCA-CoA [peroxisomal matrix]

Participates

as an event of

Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)

Authored

Jassal, B (2007-01-19)

Reviewed

D'Eustachio, P (2007-04-30)

Created

D'Eustachio, P (2007-02-19)

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