p75NTR interacts with the NOGO receptor

Stable Identifier
R-HSA-193636
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The p75NTR extracellular domain interacts with NOGO receptor (NgR), a glycosyl phosphatidylinositol (GPI)-anchored protein present as a homomultimer at the cell surface. As NgR lacks an intracellular domain, it utilizes p75NTR as a co-receptor for intracellular signalling.

Literature References
Participants
Participant Of
Orthologous Events