Efflux of 27-hydroxycholesterol

Stable Identifier
R-HSA-193812
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Efflux of 27-hydroxycholesterol
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27-hydroxycholesterol is transported from the mitochondrial matrix to the extracellular space. In humans, this event is the major source of 27-hydroxycholesterol in the blood and is the means by which the molecule, generated from cholesterol in a variety of cell types, notably macrophages, is transported to the liver for conversion to bile acids and bile salts (Babiker et al. 1999; Bjorkhem et al. 1994). While transport proteins are likely to play a role in this process, the relevant proteins have not been identified.
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Authored
D'Eustachio, P  (2007-02-28)
Reviewed
D'Eustachio, P  (2007-04-30)
Created
D'Eustachio, P  (2007-02-28)
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