11-deoxycortisol translocates to the mitochondrion

Stable Identifier
R-HSA-194025
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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11-deoxycortisol is synthesized in a reaction at the endoplasmic reticulum membrane and is further metabolized to cortisol in a reaction catalyzed by mitochondrial enzymes. The means by which 11-deoxycortisol translocates into the mitochondrial matrix, however, is unknown.

Literature References
PubMed ID Title Journal Year
15583024 Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones

Payne, AH, Hales, DB

Endocr Rev 2004
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