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ALB [extracellular region]
Stable Identifier
R-HSA-194115
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Serum albumin
Icon
Locations in the PathwayBrowser for interactor UniProt:P02786%20TFRC
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
BIL binds ALB (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
BIL:ALB scavenges O2.- (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Drug ADME (Homo sapiens)
Aspirin ADME (Homo sapiens)
ALB binds ST (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
ASA- acetylates ALB (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Ciprofloxacin ADME (Homo sapiens)
ALB binds Cipro (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Cipro:ALB dissociates (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Prednisone ADME (Homo sapiens)
ALB binds PREDL (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
ALB binds PREDN (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
PREDL:ALB dissociates (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
PREDN:ALB dissociates (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Recycling of bile acids and salts (Homo sapiens)
Bile salts and acids bind ALB (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Bile salts and acids dissociate from ALB (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Metabolism of porphyrins (Homo sapiens)
Heme biosynthesis (Homo sapiens)
ALB binds extracellular heme (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Heme degradation (Homo sapiens)
BIL binds ALB (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
BIL:ALB dissociates (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein remodeling (Homo sapiens)
HDL remodeling (Homo sapiens)
Serum albumin binds 2-lysophosphatidylcholine (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
Scavenging of heme from plasma (Homo sapiens)
Ferriheme is transferred from Albumin to Hemopexin (Homo sapiens)
ALB [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02768 ALB
Gene Names
ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Chain
signal peptide:1-18, propeptide:19-24, chain:25-609
Reference Genes
BioGPS Gene:213 ALB
COSMIC (genes):ALB ALB
CTD Gene:213 ALB
dbSNP Gene:213 ALB
ENSEMBL:ENSG00000163631 ALB
ENSEMBL_homo_sapiens_GENE:ENSG00000163631.18 ALB
HGNC:399 ALB
KEGG Gene (Homo sapiens):213 ALB
Monarch:213 ALB
NCBI Gene:213 ALB
OMIM:103600 ALB
UCSC:P02768 ALB
Reference Transcript
RefSeq:NM_000477.6 ALB
Other Identifiers
11732978_x_at
11747269_a_at
1565228_3p_s_at
1565228_PM_s_at
1565228_s_at
16967692
211298_PM_s_at
211298_s_at
213
2731193
2731194
2731195
2731198
2731199
2731201
2731202
2731206
2731207
2731209
2731211
2731212
2731214
2731218
2731220
2731223
2731225
2731227
2731228
2731229
33990_at
33991_g_at
8095628
A_14_P110095
GE79001
GO:0003677
GO:0005504
GO:0005507
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005783
GO:0005788
GO:0005794
GO:0008289
GO:0009267
GO:0015643
GO:0016209
GO:0019825
GO:0030170
GO:0031093
GO:0031410
GO:0032991
GO:0042802
GO:0043226
GO:0046872
GO:0051087
GO:0051902
GO:0070062
GO:0072562
GO:0072732
GO:0098754
GO:0098869
GO:0140272
GO:1903981
HMNXSV003004569
Hs2.406155.1.S1_3p_s_at
TC04000403.hg
U22961_s_at
g7959790_3p_x_at
Participates
as an input of
ALB binds Cipro (Homo sapiens)
ALB binds ST (Homo sapiens)
ASA- acetylates ALB (Homo sapiens)
ALB binds PREDN (Homo sapiens)
ALB binds PREDL (Homo sapiens)
Bile salts and acids bind ALB (Homo sapiens)
Serum albumin binds 2-lysophosphatidylcholine (Homo sapiens)
BIL binds ALB (Homo sapiens)
ALB binds extracellular heme (Homo sapiens)
as an output of
Cipro:ALB dissociates (Homo sapiens)
PREDL:ALB dissociates (Homo sapiens)
PREDN:ALB dissociates (Homo sapiens)
Bile salts and acids dissociate from ALB (Homo sapiens)
BIL:ALB scavenges O2.- (Homo sapiens)
BIL:ALB dissociates (Homo sapiens)
Ferriheme is transferred from Albumin to Hemopexin (Homo sapiens)
as a component of
Cipro:ALB [extracellular region] (Homo sapiens)
PREDN:ALB [extracellular region] (Homo sapiens)
PREDL:ALB [extracellular region] (Homo sapiens)
ALB:bile salts and acids [extracellular region] (Homo sapiens)
albumin:2-lysophosphatidylcholine complex [extracellular region] (Homo sapiens)
BIL:ALB [extracellular region] (Homo sapiens)
ALB:heme [extracellular region] (Homo sapiens)
Albumin:ferriheme [extracellular region] (Homo sapiens)
Other forms of this molecule
ALB(19-609) [extracellular region]
ALB [platelet alpha granule lumen]
salicyl-ALB [extracellular region]
acetyl-ALB [extracellular region]
p-ALB [endoplasmic reticulum lumen]
ALB [endoplasmic reticulum lumen]
Inferred To
ALB [extracellular region]
(Bos taurus)
ALB [extracellular region]
(Canis familiaris)
ALB [extracellular region]
(Gallus gallus)
ALB [extracellular region]
(Mus musculus)
ALB [extracellular region]
(Rattus norvegicus)
ALB [extracellular region]
(Sus scrofa)
ALB [extracellular region]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000468.1
ZINC - World Drugs
ALBU_HUMAN
OpenTargets
ENSG00000163631
ZINC - FDA approved
ALBU_HUMAN
ZINC - Substances
ALBU_HUMAN
ZINC target
P02768
ZINC - Biogenic
ALBU_HUMAN
PRO
P02768
PDB
1UOR
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7QFE
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,
4L9Q
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,
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,
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,
6WUW
,
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,
4LB2
,
1HK4
,
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,
1AO6
,
6L4K
,
6QIO
,
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,
1E7H
,
1HK2
,
7EEK
,
7Z57
,
1HA2
,
4BKE
,
1E7F
,
3JRY
,
7WOJ
,
1BKE
,
6QIP
,
2BXQ
,
2BXB
GeneCards
P02768
HPA
ENSG00000163631-ALB
Ensembl
ENSP00000295897
,
ENST00000295897
,
ENSG00000163631
Pharos - Targets
P02768
Orphanet
15485
ZINC - Predictions - Purchasable
ALBU_HUMAN
HMDB Protein
HMDBP02075
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P02768 ALB
7
ALB(19-609) [extracellular region]
(R-HSA-114609)
ALB [platelet alpha granule lumen]
(R-HSA-49865)
salicyl-ALB [extracellular region]
(R-HSA-9750694)
acetyl-ALB [extracellular region]
(R-HSA-9749660)
ALB [extracellular region]
(R-HSA-194115)
p-ALB [endoplasmic reticulum lumen]
(R-HSA-8956930)
ALB [endoplasmic reticulum lumen]
(R-HSA-8956690)
0.758
8
UniProt:P02786 TFRC
5
TFRC(1-760) [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869124)
TFRC(1-760) [Golgi membrane]
(R-HSA-434330)
TFRC(1-760) [cytoplasmic vesicle membrane]
(R-HSA-434196)
TFRC(1-760) [endosome membrane]
(R-HSA-8961829)
TFRC(1-760) [plasma membrane]
(R-HSA-917983)
0.558
2
ChEBI:49786 NICKEL(2+)
0.544
4
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