Reactome | SLC10A2 [plasma membrane]

SLC10A2 [plasma membrane]

Stable Identifier

R-HSA-194173

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

ASBT, Ileal sodium/bile acid cotransporter, Solute carrier family 10 member 2

Locations in the PathwayBrowser for interactor UniProt:O75841%20UPK1B

Expand all

External Reference Information

External Reference

UniProt:Q12908 SLC10A2

Gene Names

SLC10A2, ASBT, ISBT, NTCP2

Chain

chain:1-348

Reference Genes

BioGPS Gene:6555 SLC10A2

COSMIC (genes):SLC10A2 SLC10A2

CTD Gene:6555 SLC10A2

dbSNP Gene:6555 SLC10A2

ENSEMBL:ENSG00000125255 SLC10A2

ENSEMBL_homo_sapiens_GENE:ENSG00000125255.7 SLC10A2

HGNC:10906 SLC10A2

KEGG Gene (Homo sapiens):6555 SLC10A2

Monarch:6555 SLC10A2

NCBI Gene:6555 SLC10A2

OMIM:601295 SLC10A2

UCSC:Q12908 SLC10A2

Reference Transcript

RefSeq:NM_000452.2 SLC10A2

Other Identifiers

11729049_at

11729050_at

16780822

207095_PM_at

207095_at

3523993

3523994

3523995

3523997

3523998

3524000

3524001

3524002

3524003

35904_at

6555

7972692

A_23_P140009

GE79917

GO:0005215

GO:0005515

GO:0005886

GO:0005902

GO:0006811

GO:0006814

GO:0006869

GO:0008508

GO:0009617

GO:0015293

GO:0015721

GO:0016020

GO:0016324

GO:0055085

HMNXSV003052916

ILMN_1683670

TC13000856.hg

U67674_at

g4506972_3p_at

Inferred To

Homologues of SLC10A2 [plasma membrane] (Drosophila melanogaster)

Dmel\CG11655 [plasma membrane] (Drosophila melanogaster)

slc10a2 [plasma membrane] (Canis familiaris)

slc10a2 [plasma membrane] (Xenopus tropicalis)

Dmel\CG9903 [plasma membrane] (Drosophila melanogaster)

zgc:63998 [plasma membrane] (Danio rerio)

SLC10A2 [plasma membrane] (Bos taurus)

SLC10A2 [plasma membrane] (Caenorhabditis elegans)

SLC10A2 [plasma membrane] (Gallus gallus)

SLC10A2 [plasma membrane] (Sus scrofa)

Slc10a2 [plasma membrane] (Mus musculus)

Slc10a2 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_000443.1

ZINC - World Drugs

NTCP2_HUMAN

Guide to Pharmacology - Targets

960

OpenTargets

ENSG00000125255

ZINC - FDA approved

NTCP2_HUMAN

ZINC - Substances

NTCP2_HUMAN

ZINC - Biogenic

NTCP2_HUMAN

ZINC target

Q12908

PRO

Q12908

ZINC - Investigational

NTCP2_HUMAN

ZINC - Metabolites

NTCP2_HUMAN

GeneCards

Q12908

HPA

ENSG00000125255-SLC10A2

Ensembl

ENST00000245312, ENSG00000125255, ENSP00000245312

Pharos - Targets

Q12908

ZINC - Predictions - Purchasable

NTCP2_HUMAN

Orphanet

23732

HMDB Protein

HMDBP02461

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H0R3 TM222			0.556	3
UniProt:Q5BVD1 TTMP			0.556	3
UniProt:Q9Y6I9 TEX264	2	TEX264 [extracellular region] (R-HSA-8863002) TEX264 [platelet alpha granule lumen] (R-HSA-8863000)	0.556	3
UniProt:Q8IXM6 NRM			0.556	3
UniProt:Q8NHW4 CCL4L1	1	CCL4L1 [extracellular region] (R-HSA-8865389)	0.556	3
UniProt:P52803 EFNA5	3	EFNA5 (21-?) N-ter [extracellular region] (R-HSA-3928456) EFNA5 (?-203) C-ter [plasma membrane] (R-HSA-3928431) EFNA5 [plasma membrane] (R-HSA-2682331)	0.556	3
UniProt:O75841 UPK1B			0.556	3
UniProt:Q9NZ42 PSENEN	2	PSENEN [plasma membrane] (R-HSA-157331) PSENEN [endosome membrane] (R-HSA-9010101)	0.556	3
UniProt:Q4LDR2 CTXN3			0.556	3
UniProt:Q01628 IFITM3	1	IFITM3 [plasma membrane] (R-HSA-1015688)	0.556	3

Cite Us!