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YWHAE [cytosol]
Stable Identifier
R-HSA-194368
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
14-3-3 protein epsilon, 143E_HUMAN, 14-3-3 epsilon
Locations in the PathwayBrowser for interactor UniProt:Q86Z20 CC125
Expand all
Disease (Homo sapiens)
Diseases of programmed cell death (Homo sapiens)
Neurodegenerative Diseases (Homo sapiens)
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models (Homo sapiens)
CDC25C binds YWHAE (14-3-3-epsilon) (Homo sapiens)
YWHAE [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P62258 YWHAE
Gene Names
YWHAE
Chain
chain:1-255
Reference Genes
BioGPS Gene:7531 YWHAE
COSMIC (genes):YWHAE YWHAE
CTD Gene:7531 YWHAE
dbSNP Gene:7531 YWHAE
ENSEMBL:ENSG00000108953 YWHAE
ENSEMBL:ENSG00000274474 YWHAE
HGNC:12851 YWHAE
KEGG Gene (Homo sapiens):7531 YWHAE
Monarch:7531 YWHAE
NCBI Gene:7531 YWHAE
OMIM:605066 YWHAE
UCSC:P62258 YWHAE
Reference Transcript
RefSeq:NM_006761.4 YWHAE
Other Identifiers
0001240019
1011_s_at
11739011_s_at
11753092_s_at
11753517_s_at
11753518_x_at
11758309_s_at
210317_s_at
210996_s_at
2578538
3052111
3052117
3740125
3740127
3740128
3740129
3740130
3740131
3740132
3740133
3740134
3740135
3740139
3740141
3740143
3740144
3740147
3740148
3740149
3740156
3740157
3740158
3752151
7531
8011011
8055476
A_23_P72285
A_24_P123011
A_24_P123012
GE59242
GO:0000086
GO:0000165
GO:0000278
GO:0001764
GO:0003013
GO:0003064
GO:0003674
GO:0003723
GO:0005246
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005737
GO:0005739
GO:0005829
GO:0005856
GO:0005871
GO:0005886
GO:0005925
GO:0006464
GO:0006605
GO:0006810
GO:0006913
GO:0006950
GO:0007005
GO:0007049
GO:0007165
GO:0008150
GO:0008219
GO:0010389
GO:0015031
GO:0015459
GO:0016020
GO:0016032
GO:0019899
GO:0019903
GO:0019904
GO:0021762
GO:0021766
GO:0021987
GO:0022607
GO:0023026
GO:0030154
GO:0030424
GO:0031410
GO:0031625
GO:0032991
GO:0034504
GO:0034605
GO:0035308
GO:0035329
GO:0035556
GO:0040011
GO:0042470
GO:0042592
GO:0042802
GO:0042826
GO:0043154
GO:0043226
GO:0044325
GO:0044403
GO:0044877
GO:0045296
GO:0046827
GO:0046982
GO:0048856
GO:0048870
GO:0050815
GO:0051219
GO:0051480
GO:0055085
GO:0060306
GO:0061024
GO:0070062
GO:0086013
GO:0086091
GO:0090724
GO:0097110
GO:0097711
GO:0098978
GO:0099072
GO:1900034
GO:1900740
GO:1901016
GO:1901020
GO:1902309
GO:1905913
ILMN_1807535
ILMN_2252136
PH_hs_0029000
PH_hs_0031355
TC17000972.hg
TC17002434.hg
U54778_at
g4096984_3p_a_at
g984318_3p_a_at
Participant Of
hasComponent
CDC25C:YWHAE [cytosol]
centrosome [cytosol]
centrosome containing phosphorylated Nlp [cytosol]
centrosome without CEP164, CCP110 or CEP97 [cytosol]
cNAP-1 depleted centrosome [cytosol]
mother centriole [cytosol]
Nlp-depleted centrosome [cytosol]
YWHAE dimer [cytosol]
input
CDC25C binds YWHAE (14-3-3-epsilon)
Inferred To
Ghost homologue of YWHAE [cytosol] (Canis familiaris)
Ghost homologue of YWHAE [cytosol] (Gallus gallus)
rad24 [cytosol] (Schizosaccharomyces pombe)
ywhae2 [cytosol] (Danio rerio)
ywhae1 [cytosol] (Danio rerio)
14-3-3 epsilon [cytosol] (Mus musculus)
Ywhae [cytosol] (Rattus norvegicus)
BMH2 [cytosol] (Saccharomyces cerevisiae)
rrnad1 [cytosol] (Xenopus tropicalis)
YWHAE [cytosol] (Plasmodium falciparum)
YWHAE [cytosol] (Sus scrofa)
fttB [cytosol] (Dictyostelium discoideum)
14-3-3epsilon [cytosol] (Drosophila melanogaster)
Homologues of YWHAE [cytosol] (Danio rerio)
Cross References
RefSeq
NP_006752.1
Target Pathogen
5b354852be737e166372e6ba
OpenTargets
ENSG00000108953
GeneCards
P62258
HPA
ENSG00000108953-YWHAE
Ensembl
ENSG00000274474
,
ENSP00000264335
,
ENSP00000487356
,
ENST00000627231
,
ENSG00000108953
,
ENST00000616643
,
ENSP00000481059
,
ENSP00000461762
,
ENST00000264335
,
ENST00000571732
PRO
P62258
Orphanet
20276
PDB
3UAL
,
3UBW
,
2BR9
,
6EIH
Interactors (67)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63104 YWHAZ
2
YWHAZ [cytosol]
(R-HSA-206099)
YWHAZ [nucleoplasm]
(R-HSA-450469)
0.864
9
UniProt:P54253 ATX1
0.853
13
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.84
7
UniProt:P27348 YWHAQ
1
YWHAQ [cytosol]
(R-HSA-1445116)
0.831
7
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.823
8
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.764
6
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.738
5
UniProt:P56524 HDAC4
3
SUMO1-K559-HDAC4 [nucleoplasm]
(R-HSA-4616016)
SUMO2,3-K559-HDAC4 [nucleoplasm]
(R-HSA-4616029)
HDAC4 [nucleoplasm]
(R-HSA-351581)
0.738
4
UniProt:P04049 RAF1
54
p-S338,Y340,Y341-RAF1 [cytosol]
(R-HSA-5624465)
RAF1 [cytosol]
(R-HSA-167205)
p-S338-RAF1 [cytosol]
(R-HSA-5624469)
p-S621-RAF1 S259F [cytosol]
(R-HSA-9656124)
p-S621-RAF1 S257L [cytosol]
(R-HSA-9656121)
p-S621-RAF1 P261L [cytosol]
(R-HSA-9656106)
p-S621-RAF1 N262K [cytosol]
(R-HSA-9656101)
p-S621-RAF1 P261A [cytosol]
(R-HSA-9656103)
p-S621-RAF1 P261S [cytosol]
(R-HSA-9656113)
p-S621-RAF1 S259T [cytosol]
(R-HSA-9656130)
p-S621-RAF1 P261T [cytosol]
(R-HSA-9656115)
p-S621-RAF1 P261R [cytosol]
(R-HSA-9656110)
p-S621-RAF1 S259P [cytosol]
(R-HSA-9656127)
p-S621-RAF1 T260I [cytosol]
(R-HSA-9656136)
p-S621-RAF1 T260R [cytosol]
(R-HSA-9656139)
p-S621-RAF1 V263A [cytosol]
(R-HSA-9656148)
p-S621-RAF1 R256S [cytosol]
(R-HSA-9656119)
p-S621-RAF1 T491I [cytosol]
(R-HSA-9656143)
p-S621-RAF1 D486N [cytosol]
(R-HSA-9656088)
p-S621-RAF1 S427G [cytosol]
(R-HSA-9656134)
p-S621-RAF1 L613V [cytosol]
(R-HSA-9656098)
p-S621-RAF1 G361A [cytosol]
(R-HSA-9656092)
p-S621-RAF1 G370R [cytosol]
(R-HSA-9656094)
p-S621-RAF1 D486G [cytosol]
(R-HSA-9656085)
p-S621-RAF1 T491R [cytosol]
(R-HSA-9656145)
p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol]
(R-HSA-9656026)
p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol]
(R-HSA-9656070)
p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol]
(R-HSA-9656035)
p-S338,Y341,S494,S621-RAF1 T491I [cytosol]
(R-HSA-9656019)
p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol]
(R-HSA-9656029)
p-S338,Y341,T492,S494,S621 RAF1 G370R [cytosol]
(R-HSA-9656031)
p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol]
(R-HSA-9656023)
p-S338,Y341,S494,S621 RAF1 T491R [cytosol]
(R-HSA-9656017)
p-S338,Y341,T492,S494,S621 RAF1 S259F [cytosol]
(R-HSA-9656062)
p-S338,Y341,T492,S494,S621 RAF1 P261A [cytosol]
(R-HSA-9656041)
p-S338,Y341,T492,S494,S621 RAF1 S257L [cytosol]
(R-HSA-9656058)
p-S338,Y341,T492,S494,S621 RAF1 P261L [cytosol]
(R-HSA-9656043)
p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol]
(R-HSA-9656053)
p-S338,Y341,T492,S494,S621 RAF1 N262K [cytosol]
(R-HSA-9656037)
p-S338,Y341,T492,S494,S621 RAF1 P261S [cytosol]
(R-HSA-9656050)
p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol]
(R-HSA-9656067)
p-S338,Y341,T492,S494,S621 RAF1 T260R [cytosol]
(R-HSA-9656077)
p-S338,Y341,T492,S494,S621 RAF1 P261R [cytosol]
(R-HSA-9656047)
p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol]
(R-HSA-9656056)
p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol]
(R-HSA-9656074)
p-S338,Y341,T492,S494,S621 RAF1 V263A [cytosol]
(R-HSA-9656080)
p-S338,Y341,T492,S494,S621 RAF1 S259P [cytosol]
(R-HSA-9656065)
hyperphosphorylated RAF1 [plasma membrane]
(R-HSA-5675193)
p-S621-RAF1 [plasma membrane]
(R-HSA-206222)
p-Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5675420)
p-S259,S621-RAF1 [cytosol]
(R-HSA-109786)
p-S621-RAF1 [cytosol]
(R-HSA-206028)
p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5672665)
p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-HSA-5672664)
0.738
5
UniProt:P46937 YAP1
7
p-Y-YAP1 [cytosol]
(R-HSA-8937843)
p-Y407-YAP1 [nucleoplasm]
(R-HSA-8956661)
p-Y-YAP1 [nucleoplasm]
(R-HSA-8937857)
p-S127-YAP1 [cytosol]
(R-HSA-2028553)
p-5S-YAP1 [cytosol]
(R-HSA-2028554)
YAP1 [nucleoplasm]
(R-HSA-1253322)
YAP1 [cytosol]
(R-HSA-1253345)
0.708
5
UniProt:P30304 CDC25A
6
p-S123-CDC25A [nucleoplasm]
(R-HSA-143488)
CDC25A [nucleoplasm]
(R-HSA-143487)
CDC25A [cytosol]
(R-HSA-157410)
p-S123-CDC25A [cytosol]
(R-HSA-69588)
p-S40,S116,S261-CDC25A [nucleoplasm]
(R-HSA-8863634)
PolyUb-CDC25A [cytosol]
(R-HSA-6782810)
0.69
5
UniProt:P35568 IRS1
5
p-Y-IRS1 [cytosol]
(R-HSA-74772)
p-Y-IRS1 [plasma membrane]
(R-HSA-198366)
IRS1 [cytosol]
(R-HSA-74769)
IRS1 [plasma membrane]
(R-HSA-2425392)
p-6Y-IRS1 [plasma membrane]
(R-HSA-2445090)
0.682
6
UniProt:Q99759 MAP3K3
1
MAP3K3 [cytosol]
(R-HSA-507725)
0.669
3
UniProt:O15151 MDM4
5
PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm]
(R-HSA-6804938)
PolyUb-MDM4 [nucleoplasm]
(R-HSA-6782502)
p-S346,S367,S403-MDM4 [nucleoplasm]
(R-HSA-349441)
p-S403-MDM4 [nucleoplasm]
(R-HSA-349461)
MDM4 [nucleoplasm]
(R-HSA-349430)
0.669
3
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.667
3
UniProt:Q92934 BAD
4
p-S99-BAD [cytosol]
(R-HSA-198335)
BAD [cytosol]
(R-HSA-50662)
BAD [mitochondrial outer membrane]
(R-HSA-114242)
p-S128-BAD [cytosol]
(R-HSA-217297)
0.667
4
UniProt:Q13671 RIN1
1
RIN1 [cytosol]
(R-HSA-8875287)
0.659
3
UniProt:Q9GZV5 WWTR1
3
WWTR1 [cytosol]
(R-HSA-1629773)
WWTR1 [nucleoplasm]
(R-HSA-1629775)
p-S89-WWTR1 [cytosol]
(R-HSA-2028665)
0.659
3
UniProt:Q99469 STAC
0.656
3
UniProt:P15056 BRAF
68
BRAF-MACF1fusion [cytosol]
(R-HSA-6802402)
p-S,T-BRAF [cytosol]
(R-HSA-169856)
p-BRAF-MACF1 fusion [cytosol]
(R-HSA-6802536)
BRAF [cytosol]
(R-HSA-167224)
BRAF E501G [cytosol]
(R-HSA-9651132)
BRAF D594N [cytosol]
(R-HSA-6802299)
BRAF D638E [cytosol]
(R-HSA-9651125)
BRAF G596R [cytosol]
(R-HSA-6802385)
BRAF D594V [cytosol]
(R-HSA-6802305)
BRAF G596V [cytosol]
(R-HSA-9651138)
BRAF G466E [cytosol]
(R-HSA-6802374)
BRAF D594G [cytosol]
(R-HSA-6802295)
BRAF L505H [cytosol]
(R-HSA-9648845)
BRAF F595L [cytosol]
(R-HSA-6802316)
BRAF L597V [cytosol]
(R-HSA-6802397)
BRAF G464E [cytosol]
(R-HSA-6802369)
BRAF N581D [cytosol]
(R-HSA-9651152)
BRAF E586K [cytosol]
(R-HSA-6802308)
BRAF V600K [cytosol]
(R-HSA-6802502)
BRAF A246P [cytosol]
(R-HSA-9651123)
BRAF G469V [cytosol]
(R-HSA-9648620)
BRAF T244P [cytosol]
(R-HSA-9651165)
BRAF G469R [cytosol]
(R-HSA-9648621)
BRAF L597R [cytosol]
(R-HSA-9648617)
BRAF G469E [cytosol]
(R-HSA-9648618)
BRAF L597Q [cytosol]
(R-HSA-9648619)
BRAF G466A [cytosol]
(R-HSA-9648613)
BRAF G466V [cytosol]
(R-HSA-9648838)
BRAF N581S [cytosol]
(R-HSA-9648850)
BRAF G464V [cytosol]
(R-HSA-9648611)
p-BRAF L597V [plasma membrane]
(R-HSA-8936647)
p-BRAF L505H [plasma membrane]
(R-HSA-9648862)
p-BRAF G464E [plasma membrane]
(R-HSA-8936645)
p-BRAF F595L [plasma membrane]
(R-HSA-8936641)
p-BRAF A246P [plasma membrane]
(R-HSA-9651188)
p-BRAF E586K [plasma membrane]
(R-HSA-8936639)
p-BRAF N581D [plasma membrane]
(R-HSA-9651191)
p-BRAF V600K [plasma membrane]
(R-HSA-8936651)
p-BRAF G464V [plasma membrane]
(R-HSA-9648633)
p-BRAF T244P [plasma membrane]
(R-HSA-9651194)
p-BRAF G469E [plasma membrane]
(R-HSA-9648634)
p-BRAF G466V [plasma membrane]
(R-HSA-9648859)
p-BRAF G469V [plasma membrane]
(R-HSA-9648628)
p-BRAF G466A [plasma membrane]
(R-HSA-9648629)
p-BRAF L597Q [plasma membrane]
(R-HSA-9648630)
p-BRAF L597R [plasma membrane]
(R-HSA-9648631)
p-BRAF N581S [plasma membrane]
(R-HSA-9648866)
p-BRAF G469R [plasma membrane]
(R-HSA-9648627)
BRAF 599dupT [cytosol]
(R-HSA-6802281)
BRAF G534R [cytosol]
(R-HSA-9651134)
BRAF S467A [cytosol]
(R-HSA-9651161)
BRAF K601N [cytosol]
(R-HSA-9648857)
BRAF G469A [cytosol]
(R-HSA-6802381)
BRAF L485F [cytosol]
(R-HSA-9651147)
BRAF Q257R [cytosol]
(R-HSA-9651157)
BRAF K499E [cytosol]
(R-HSA-9651142)
BRAF V600E [cytosol]
(R-HSA-6802498)
BRAF K601E [cytosol]
(R-HSA-9648833)
BRAF V600E V169_M438del [cytosol]
(R-HSA-6802489)
BRAF V600E V47_D380del [cytosol]
(R-HSA-6802491)
BRAF V600E V47_M438del [cytosol]
(R-HSA-6802495)
V600E BRAF V169_D380del [cytosol]
(R-HSA-6802486)
p-S445,S729-BRAF [plasma membrane]
(R-HSA-8933622)
hyperphosphorylated BRAF [plasma membrane]
(R-HSA-5675199)
p-S365,S445,S729 BRAF [cytosol]
(R-HSA-5672667)
p-S445,T599,S602,S729 BRAF [plasma membrane]
(R-HSA-5672679)
p-S445,S729-BRAF [cytosol]
(R-HSA-5672673)
p-S445,T599,S602,S729 BRAF [cytosol]
(R-HSA-5672676)
0.643
4
UniProt:Q9Y3M2 CBY1
3
CBY1 [nucleoplasm]
(R-HSA-3769210)
pS20-CBY1 [nucleoplasm]
(R-HSA-3769356)
pS20-CBY1 [cytosol]
(R-HSA-3769354)
0.638
4
UniProt:O92972-PRO_0000278742
0.625
5
UniProt:Q13233 MAP3K1
2
p-T1400,T1412-MAP3K1 [cytosol]
(R-HSA-2685607)
MAP3K1 [cytosol]
(R-HSA-166866)
0.621
3
UniProt:Q9UKT5 FBXO4
1
FBXO4 [cytosol]
(R-HSA-391298)
0.612
5
UniProt:Q9Y2U5 M3K2
0.602
3
UniProt:Q14678-2 KANK1
0.602
3
UniProt:P30305 CDC25B
3
CDC25B [cytosol]
(R-HSA-157412)
p-S50,T69,S160,S321,S470-CDC25B [cytosol]
(R-HSA-8863644)
CDC25B [nucleoplasm]
(R-HSA-69734)
0.573
3
UniProt:P58340 MLF1
0.558
3
UniProt:Q86Z20 CC125
0.556
3
UniProt:Q06251 YL177
0.556
3
UniProt:Q7L804 RAB11FIP2
1
RAB11FIP2 [cytoplasmic vesicle membrane]
(R-HSA-2028707)
0.556
3
UniProt:P56524-2 HDAC4
0.556
3
UniProt:Q08981 ACM1
0.556
3
UniProt:Q9NRI5 DISC1
0.553
3
UniProt:Q99683 MAP3K5
1
MAP3K5 [cytosol]
(R-HSA-167709)
0.547
2
UniProt:Q13111 CAF1A
0.547
2
UniProt:P10398 ARAF
4
p-S299,S302,T452,T455,S576 ARAF [plasma membrane]
(R-HSA-5672648)
p-S299,S302,T452,T455,S576 ARAF [cytosol]
(R-HSA-5672646)
p-S576 ARAF [cytosol]
(R-HSA-5672681)
p-S214,S576 ARAF [cytosol]
(R-HSA-5672639)
0.547
3
UniProt:P08069 IGF1R
3
IGF1R(31-736) [plasma membrane]
(R-HSA-2404169)
IGF1R(741-1367) [plasma membrane]
(R-HSA-2404180)
p-Y1161,Y1165,Y1166-IGF1R(741-1367) [plasma membrane]
(R-HSA-2404172)
0.545
4
UniProt:Q13627 DYRK1A
1
DYRK1A [nucleoplasm]
(R-HSA-1362267)
0.544
3
UniProt:Q6R327 RICTOR
1
RICTOR [cytosol]
(R-HSA-198632)
0.527
2
UniProt:O43900 PRIC3
0.527
2
UniProt:Q9UJM3 ERRFI
0.527
2
UniProt:Q9UQL6 HDAC5
1
HDAC5 [nucleoplasm]
(R-HSA-3004533)
0.527
3
UniProt:Q02750 MAP2K1
27
MAP2K1(2-8) [cytosol]
(R-HSA-5211342)
MAP2K1(9-393) [cytosol]
(R-HSA-5211353)
MAP2K1 F53S [cytosol]
(R-HSA-9652034)
MAP2K1 D67N [cytosol]
(R-HSA-9652016)
MAP2K1 Q56P [cytosol]
(R-HSA-9652064)
MAP2K1 E203K [cytosol]
(R-HSA-9652023)
MAP2K1 V60E [cytosol]
(R-HSA-9652067)
MAP2K1 P124S [cytosol]
(R-HSA-9652062)
MAP2K1 Y130C [cytosol]
(R-HSA-9652101)
MAP2K1 C121S [cytosol]
(R-HSA-9652013)
MAP2K1 G128V [cytosol]
(R-HSA-9652047)
MAP2K1 F53L [cytosol]
(R-HSA-9652031)
MAP2K1 K57N [cytosol]
(R-HSA-9652050)
MAP2K1 K57T [cytosol]
(R-HSA-9652052)
MAP2K1 F53V [cytosol]
(R-HSA-9652038)
MAP2K1 D67Y [cytosol]
(R-HSA-9652019)
MAP2K1 G128D [cytosol]
(R-HSA-9652043)
MAP2K1 P124L [cytosol]
(R-HSA-9652056)
MAP2K1 F53Y [cytosol]
(R-HSA-9652041)
MAP2K1 E44_E57del [cytosol]
(R-HSA-9652026)
MAP2K1 P124Q [cytosol]
(R-HSA-9652058)
MAP2K1 F53C [cytosol]
(R-HSA-9652028)
p-S,218, S222,T292 MAP2K1 [cytosol]
(R-HSA-5674490)
MAP2K1 [cytosol]
(R-HSA-59502)
p-T286,T292-MAP2K1 [cytosol]
(R-HSA-112374)
p-S218,S222,T286,T292-MAP2K1 [cytosol]
(R-HSA-112339)
p-S218,S222-MAP2K1 [cytosol]
(R-HSA-109837)
0.527
3
UniProt:Q61337 Bad
6
Bad [mitochondrial outer membrane]
(R-MMU-114242)
phospho-Bad [cytosol]
(R-MMU-217297)
p-S136-Bad [cytosol]
(R-MMU-3139049)
Bad [cytosol]
(R-MMU-3139043)
phospho-Bad [cytosol]
(R-MMU-198335)
Bad [cytosol]
(R-MMU-50662)
0.527
2
UniProt:P00519 ABL1
5
p-Y226,Y393-ABL1 [nucleoplasm]
(R-HSA-8985251)
ABL1 [cytosol]
(R-HSA-375987)
p-S456-ABL1 [nucleoplasm]
(R-HSA-5686576)
ABL1 [nucleoplasm]
(R-HSA-5686579)
p-Y226,Y393-ABL1 [cytosol]
(R-HSA-8942610)
0.527
2
UniProt:P22681 CBL
39
CBL R420Q [cytosol]
(R-HSA-9706186)
CBL R420G [cytosol]
(R-HSA-9706203)
CBL Y371H [cytosol]
(R-HSA-9706680)
CBL H398Y [cytosol]
(R-HSA-9706639)
CBL P417A [cytosol]
(R-HSA-9706636)
CBL S376F [cytosol]
(R-HSA-9706643)
CBL del366-409 [cytosol]
(R-HSA-9706179)
CBL del366-477 [cytosol]
(R-HSA-9706176)
CBL R499L [cytosol]
(R-HSA-9706678)
CBL L380P [cytosol]
(R-HSA-9706630)
CBL L287R [cytosol]
(R-HSA-9706693)
CBL L380R [cytosol]
(R-HSA-9706635)
CBL G375P [cytosol]
(R-HSA-9706219)
CBL P417L [cytosol]
(R-HSA-9706634)
CBL H398Q [cytosol]
(R-HSA-9706633)
CBL P417R [cytosol]
(R-HSA-9706632)
CBL R499* [cytosol]
(R-HSA-9706670)
CBL H398R [cytosol]
(R-HSA-9706638)
CBL H398P [cytosol]
(R-HSA-9706637)
CBL G375fs*16 [cytosol]
(R-HSA-9706211)
CBL R420* [cytosol]
(R-HSA-9706208)
CBL H398D [cytosol]
(R-HSA-9706631)
CBL Y371C [cytosol]
(R-HSA-9706694)
CBL G375S [cytosol]
(R-HSA-9706214)
CBL Y371D [cytosol]
(R-HSA-9706687)
CBL Y371S [cytosol]
(R-HSA-9706674)
CBL P417S [cytosol]
(R-HSA-9706642)
CBL H398N [cytosol]
(R-HSA-9706641)
CBL R420P [cytosol]
(R-HSA-9706193)
CBL Y371N [cytosol]
(R-HSA-9706679)
CBL R499Q [cytosol]
(R-HSA-9706677)
CBL R420L [cytosol]
(R-HSA-9706197)
CBL P417H [cytosol]
(R-HSA-9706644)
p-Y371-CBL [plasma membrane]
(R-HSA-182923)
p-Y-CBL [cytosol]
(R-HSA-8875457)
p-Y371-CBL [cytosol]
(R-HSA-182940)
PolyUb,p-Y700,Y731,Y774-CBL [cytosol]
(R-HSA-8848826)
p-Y700,Y731,Y774-CBL [cytosol]
(R-HSA-912656)
CBL [cytosol]
(R-HSA-112199)
0.527
2
UniProt:Q00613 HSF1
11
p-S303-HSF1 [cytosol]
(R-HSA-4793927)
p-S121-HSF1 [cytosol]
(R-HSA-4793906)
p-S307-HSF1 [cytosol]
(R-HSA-4793929)
p-S303,307-HSF1 [cytosol]
(R-HSA-4793922)
HSF1 [nucleoplasm]
(R-HSA-5082385)
hC36,103-HSF1 [cytosol]
(R-HSA-4793916)
p-S230-hC36,103-HSF1 [nucleoplasm]
(R-HSA-5082361)
p-S326-hC36,103-HSF1 [nucleoplasm]
(R-HSA-5082355)
Ac-K80-hC36,103-HSF1 [nucleoplasm]
(R-HSA-5097238)
HSF1 [cytosol]
(R-HSA-3371452)
hC36,103-HSF1 [nucleoplasm]
(R-HSA-3371416)
0.527
2
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.527
3
UniProt:O35244
3
Prdx6 [azurophil granule lumen]
(R-RNO-6798744)
Prdx6 [extracellular region]
(R-RNO-6806198)
Prdx6 [cytosol]
(R-RNO-3343670)
0.524
2
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.508
3
UniProt:P61962 DCAF7
2
DCAF7 [nucleoplasm]
(R-HSA-8863312)
Unfolded DCAF7 [cytosol]
(R-HSA-6813821)
0.508
3
UniProt:Q9NRR6 INPP5E
2
INPP5E [cytosol]
(R-HSA-1604585)
INPP5E [cilium]
(R-HSA-5624872)
0.508
3
UniProt:O94921 CDK14
0.508
3
UniProt:Q96AP0 ACD
1
ACD [nucleoplasm]
(R-HSA-174889)
0.508
2
UniProt:Q5SW79 CE170
0.508
2
UniProt:O00257-3 CBX4
0.499
2
UniProt:P09622 DLD
1
DLD [mitochondrial matrix]
(R-HSA-69978)
0.499
5
UniProt:P36957 DLST
2
Lipo-K110-DLST [mitochondrial matrix]
(R-HSA-69993)
DLST [mitochondrial matrix]
(R-HSA-6792574)
0.499
4
UniProt:P21796 VDAC1
4
PolyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-6783079)
VDAC1 [mitochondrial intermembrane space]
(R-HSA-1267960)
K48polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-5205624)
VDAC1 [mitochondrial outer membrane]
(R-HSA-1267988)
0.499
5
UniProt:Q51451 Q51451
0.469
2
UniProt:P30041 PRDX6
3
PRDX6 [azurophil granule lumen]
(R-HSA-6798744)
PRDX6 [extracellular region]
(R-HSA-6806198)
PRDX6 [cytosol]
(R-HSA-3343670)
0.463
2
UniProt:Q76353 Q76353
0.462
2
UniProt:P26045 PTPN3
3
p-S459 PTPN3 [cytosol]
(R-HSA-8868111)
PTPN3 [plasma membrane]
(R-HSA-5490317)
PTPN3 [cytosol]
(R-HSA-8867650)
0.462
2
UniProt:P51957-2 NEK4
0.462
2
UniProt:P51957-1 NEK4
0.462
2
UniProt:Q6PJG9 LRFN4
1
SALM3 [plasma membrane]
(R-HSA-197883)
0.462
3
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