Reactome | RTN4 [plasma membrane]

RTN4 [plasma membrane]

Stable Identifier

R-HSA-194556

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

NOGO, Reticulon 4, RTN4_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NQC3 RTN4

Gene Names

RTN4, KIAA0886, NOGO, My043, SP1507

Chain

chain:1-1192

Reference Genes

BioGPS Gene:57142 RTN4

COSMIC (genes):RTN4 RTN4

CTD Gene:57142 RTN4

dbSNP Gene:57142 RTN4

ENSEMBL:ENSG00000115310 RTN4

HGNC:14085 RTN4

KEGG Gene (Homo sapiens):57142 RTN4

Monarch:57142 RTN4

NCBI Gene:57142 RTN4

OMIM:604475 RTN4

UCSC:Q9NQC3 RTN4

Reference Transcript

Other Identifiers

0000060546

0002850390

11718592_s_at

11718593_x_at

11719933_x_at

11738035_s_at

11744360_x_at

11749059_x_at

11752131_a_at

11753588_x_at

16897637

210968_s_at

211509_s_at

214629_x_at

2553581

2553582

2553583

2553584

2553585

2553586

2553587

2553588

2553589

2553590

2553591

2553593

2553595

2553597

2553610

2553614

2553615

2553620

2553621

2553622

2553628

2553629

2553630

2553631

2553633

2553640

2553643

2553647

2553648

2553649

2553650

2553651

2553652

31536_at

57142

8052204

A_23_P56933

A_33_P3233550

GE53561

GE663571

GE80778

GO:0000902

GO:0001825

GO:0003674

GO:0003723

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005635

GO:0005737

GO:0005783

GO:0005789

GO:0005886

GO:0006915

GO:0007165

GO:0007399

GO:0007413

GO:0008150

GO:0008219

GO:0008283

GO:0009790

GO:0010634

GO:0014069

GO:0016020

GO:0016021

GO:0019899

GO:0021801

GO:0022607

GO:0030054

GO:0030154

GO:0030176

GO:0030308

GO:0030517

GO:0031625

GO:0033601

GO:0034165

GO:0040007

GO:0040011

GO:0042592

GO:0042981

GO:0042995

GO:0043025

GO:0043226

GO:0045296

GO:0048646

GO:0048856

GO:0048870

GO:0050771

GO:0050821

GO:0051292

GO:0051897

GO:0051960

GO:0060317

GO:0061024

GO:0061462

GO:0065003

GO:0071782

GO:0071786

GO:0071787

GO:0090156

GO:0098826

GO:1905552

GO:1905580

GO:1990809

GO:2000172

Hs.65450.7.A2_3p_a_at

ILMN_1693598

ILMN_1730611

ILMN_1748983

ILMN_2352036

PH_hs_0025494

TC02004241.hg

g5821139_3p_a_at

Participant Of

hasMember

RTN4,MAG,OMG [plasma membrane]

Inferred To

Rtn4 [plasma membrane] (Mus musculus)

Rtn4 [plasma membrane] (Rattus norvegicus)

rtn4a [plasma membrane] (Danio rerio)

RTN4 [plasma membrane] (Canis familiaris)

RTN4 [plasma membrane] (Sus scrofa)

RTN4 [plasma membrane] (Xenopus tropicalis)

Rtnl1 [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

XP_016860007.1, NP_001308791.1, NP_001308792.1, NP_722550.1, NP_065393.1, NP_008939.1, NP_997403.1, NP_997404.1, NP_001308833.1, XP_016860008.1, NP_001308788.1, NP_001308790.1, XP_005264491.1, NP_001308789.1

OpenTargets

ENSG00000115310

GeneCards

Q9NQC3

HPA

ENSG00000115310-RTN4

Ensembl

ENST00000405240, ENSG00000115310, ENST00000317610, ENSP00000337838, ENSP00000385650, ENSP00000384471, ENST00000394609, ENST00000337526, ENSP00000378107, ENSP00000350365, ENST00000404909, ENSP00000378109, ENST00000394611, ENSP00000322147, ENSP00000349944, ENST00000357376, ENST00000357732

PRO

Q9NQC3

PDB

2G31, 2JV5

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	8	N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) M [virion membrane] (R-COV-9694320) N-glycan M [virion membrane] (R-COV-9694385)	0.643	3
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.558	2
UniProt:O95197 RTN3	1	RTN3 [plasma membrane] (R-HSA-8849907)	0.553	2
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	4