Reactome | RHOBTB2 [endosome membrane]

RHOBTB2 [endosome membrane]

Stable Identifier

R-HSA-194907

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

RhoBTB2

Locations in the PathwayBrowser for interactor UniProt:O95704 APBB3

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Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RHOBTB GTPase Cycle (Homo sapiens)
        
        RHOBTB2 GTPase cycle (Homo sapiens)
        
        RHOBTB2 binds GTP (Homo sapiens)
        
        RHOBTB2 [endosome membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BYZ6 RHOBTB2

Gene Names

RHOBTB2, DBC2, KIAA0717

Chain

chain:1-727

Reference Genes

BioGPS Gene:23221 RHOBTB2

COSMIC (genes):RHOBTB2 RHOBTB2

CTD Gene:23221 RHOBTB2

dbSNP Gene:23221 RHOBTB2

ENSEMBL:ENSG00000008853 RHOBTB2

HGNC:18756 RHOBTB2

KEGG:hsa:23221 RHOBTB2

Monarch:23221 RHOBTB2

NCBI Gene:23221 RHOBTB2

OMIM:607352 RHOBTB2

UCSC:Q9BYZ6 RHOBTB2

Reference Transcript

Other Identifiers

11720233_a_at

11720234_at

11720235_a_at

1554586_PM_a_at

1554586_a_at

17066791

209441_PM_at

209441_at

23221

3089742

3089743

3089746

3089747

3089748

3089753

3089754

3089755

3089756

3089757

3089758

3089759

3089760

3089761

3089762

3089763

3089764

3089765

3089766

3089767

3089769

3089770

3089771

3089772

3089773

3089774

3089775

3089776

3089777

3089778

3089779

3089781

3089783

3089784

36540_at

8145227

A_14_P118703

A_14_P129251

A_23_P20427

GE81993

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005886

GO:0006897

GO:0007015

GO:0007163

GO:0007264

GO:0010008

GO:0016192

GO:0016787

GO:0019901

GO:0032488

HMNXSV003015479

Hs2.62113.2.S1_3p_s_at

ILMN_2195957

PH_hs_0024217

TC08000178.hg

g12667515_3p_at

g12667515_3p_x_at

Participates

as a component of

RHOBTB2:GTP [endosome membrane] (Homo sapiens)

as an input of

RHOBTB2 binds GTP (Homo sapiens)

Inferred To

RHOBTB2 [endosome membrane] (Bos taurus)

RHOBTB2 [endosome membrane] (Canis familiaris)

RHOBTB2 [endosome membrane] (Dictyostelium discoideum)

RHOBTB2 [endosome membrane] (Gallus gallus)

RHOBTB2 [endosome membrane] (Mus musculus)

RHOBTB2 [endosome membrane] (Sus scrofa)

Rhobtb2 [endosome membrane] (Rattus norvegicus)

RhoBTB [endosome membrane] (Drosophila melanogaster)

rhobtb2 [endosome membrane] (Xenopus tropicalis)

Homologues of RHOBTB2 [endosome membrane] (Dictyostelium discoideum)

racQ [endosome membrane] (Dictyostelium discoideum)

racP [endosome membrane] (Dictyostelium discoideum)

Cross References

ENSEMBL

ENSP00000429141, ENSP00000427926, ENST00000519685, ENST00000251822, ENSP00000251822, ENST00000522948, ENSG00000008853

OpenTargets

ENSG00000008853

GeneCards

RHOBTB2

HPA

ENSG00000008853-RHOBTB2

PRO

Q9BYZ6

Pharos - Targets

Q9BYZ6

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95704 APBB3			0.527	3
UniProt:Q13618 CUL3	3	CUL3 [cytosol] (R-HSA-975979) CUL3 [nucleoplasm] (R-HSA-5635033) G76-NEDD8-K712-CUL3 [cytosol] (R-HSA-8952516)	0.527	2
UniProt:O95147 DUS14			0.527	2
UniProt:Q9Y4X5 ARIH1	1	ARIH1 [cytosol] (R-HSA-1678825)	0.527	2