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CSNK1A1 [cytosol]
Stable Identifier
R-HSA-195263
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
CK1alpha, CSNK1A1
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by WNT in cancer (Homo sapiens)
Signaling by AMER1 mutants (Homo sapiens)
Truncations of AMER1 destabilize the destruction complex (Homo sapiens)
Truncated AMER1 mutants destabilize the destruction complex (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Signaling by APC mutants (Homo sapiens)
APC truncation mutants have impaired AXIN binding (Homo sapiens)
APC truncation mutants have impaired AXIN binding (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Signaling by AXIN mutants (Homo sapiens)
AXIN missense mutants destabilize the destruction complex (Homo sapiens)
AXIN mutants destabilize the destruction complex (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Signaling by CTNNB1 phospho-site mutants (Homo sapiens)
S33 mutants of beta-catenin aren't phosphorylated (Homo sapiens)
CTNNB1 S33 mutants aren't phosphorylated by GSK3beta (Homo sapiens)
pS37,T41,S45-CTNNB1 S33 mutants:Axin:GSK3:CK1alpha:APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
S37 mutants of beta-catenin aren't phosphorylated (Homo sapiens)
CTNNB1 S37 mutants aren't phosphorylated by GSK3beta (Homo sapiens)
pT41,S45-CTNNB1 S37 mutants:Axin:GSK3:CK1alpha:APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
S45 mutants of beta-catenin aren't phosphorylated (Homo sapiens)
CTNNB1 S45 mutants aren't phosphorylated by CK1alpha (Homo sapiens)
CTNNB1 S45 mutants:AXIN:GSK3:CK1alpha:APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
T41 mutants of beta-catenin aren't phosphorylated (Homo sapiens)
CTNNB1 T41 mutants aren't phosphorylated by GSK3beta (Homo sapiens)
pS45-CTNNB1 T41 mutants:Axin:GSK3:CK1alpha:APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Signaling by GSK3beta mutants (Homo sapiens)
Misspliced GSK3beta mutants stabilize beta-catenin levels (Homo sapiens)
pS45-beta-catenin:p-Axin:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'off' state (Homo sapiens)
Degradation of GLI2 by the proteasome (Homo sapiens)
CK1 phosphorylates p-GLI2 (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
GLI3 is processed to GLI3R by the proteasome (Homo sapiens)
CK1 phosphorylates p-GLI3 (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Signaling by WNT (Homo sapiens)
Degradation of beta-catenin by the destruction complex (Homo sapiens)
AXIN is phosphorylated in the destruction complex (Homo sapiens)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Assembly of the destruction complex (Homo sapiens)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Homo sapiens)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Homo sapiens)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Association of beta-catenin with the destruction complex (Homo sapiens)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Beta-catenin phosphorylation cascade (Homo sapiens)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Homo sapiens)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Homo sapiens)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Homo sapiens)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Homo sapiens)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Degradation of ubiquitinated beta catenin by the proteasome (Homo sapiens)
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Homo sapiens)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Homo sapiens)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Homo sapiens)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Homo sapiens)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Homo sapiens)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Homo sapiens)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Homo sapiens)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
Phosphorylation of APC component of the destruction complex (Homo sapiens)
CK1alpha (GSK3) [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Homo sapiens)
Beta-catenin is released from the destruction complex (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
CTNNB1:AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
PP2A dephosphorylates AXIN, APC and CTNNB1 in the destruction complex (Homo sapiens)
CTNNB1:AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Homo sapiens)
CSNK1A1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48729 CSNK1A1
Gene Names
CSNK1A1
Chain
initiator methionine:1, chain:2-337
Reference Genes
BioGPS Gene:1452 CSNK1A1
COSMIC (genes):CSNK1A1 CSNK1A1
CTD Gene:1452 CSNK1A1
dbSNP Gene:1452 CSNK1A1
ENSEMBL:ENSG00000113712 CSNK1A1
HGNC:2451 CSNK1A1
KEGG Gene (Homo sapiens):1452 CSNK1A1
Monarch:1452 CSNK1A1
NCBI Gene:1452 CSNK1A1
OMIM:600505 CSNK1A1
UCSC:P48729 CSNK1A1
Reference Transcript
RefSeq:NM_001892.5 CSNK1A1
RefSeq:NM_001271742.1 CSNK1A1
RefSeq:NM_001271741.1 CSNK1A1
RefSeq:NM_001025105.2 CSNK1A1
Other Identifiers
0002570706
11736307_x_at
11736308_s_at
11736309_a_at
11736310_x_at
11748687_s_at
11748688_x_at
11756304_x_at
11762434_s_at
11763318_s_at
1452
206562_s_at
208865_3p_at
208865_at
208866_at
208867_s_at
213086_s_at
213860_x_at
2880885
2880886
2880902
2880906
2880907
2880908
2880909
2880910
2880911
2880912
2880913
2880914
2880915
2880923
2880925
2880927
2880929
2880931
2880933
2880934
2880935
2880936
2880937
2880938
2880939
2880940
2880941
2880942
2880943
2880944
2880945
2880979
2880999
3509988
3618298
3618307
40184_at
73359_at
8115022
81830_r_at
A_24_P183292
A_24_P251899
GE512141
GE57745
GE85967
GO:0000166
GO:0000775
GO:0000776
GO:0000777
GO:0000902
GO:0003674
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005847
GO:0005856
GO:0005929
GO:0006464
GO:0006468
GO:0007010
GO:0007030
GO:0007049
GO:0007165
GO:0007166
GO:0007267
GO:0008150
GO:0009056
GO:0016020
GO:0016055
GO:0016301
GO:0016310
GO:0016607
GO:0016740
GO:0018105
GO:0022607
GO:0030877
GO:0032436
GO:0032991
GO:0036064
GO:0042995
GO:0043167
GO:0043226
GO:0045095
GO:0045104
GO:0048856
GO:0051301
GO:0065003
GO:0090090
GO:1904424
GO:1904885
GO:1904886
GO:1990904
Hs.144477.0.S2_3p_s_at
Hs.144477.0.S2_3p_x_at
Hs.144477.0.S3_3p_at
Hs.144477.0.S3_3p_x_at
Hs.84264.3.A1_3p_s_at
ILMN_1775058
ILMN_1785988
ILMN_2364174
L37042_at
PH_hs_0029731
TC05001924.hg
g4503088_3p_a_at
g4503088_3p_x_at
g7770258_RC_3p_a_at
Participant Of
input
APC truncation mutants have impaired AXIN binding
Assembly of the destruction complex
AXIN mutants destabilize the destruction complex
Truncated AMER1 mutants destabilize the destruction complex
hasComponent
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
p-AXIN:GSK3 del304-316:CK1alpha:APC:PP2A:AMER1 complex [cytosol]
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol]
hasMember
CK1alpha (GSK3) [cytosol]
output
Beta-catenin is released from the destruction complex
Other forms of this molecule
CSNK1A1 [cilium]
Inferred To
Csnk1a1 [cytosol] (Mus musculus)
Csnk1a1 [cytosol] (Rattus norvegicus)
CKIalpha like [cytosol] (Drosophila melanogaster)
csnk1a1 [cytosol] (Danio rerio)
Dmel\CG2577 [cytosol] (Drosophila melanogaster)
Homologues of CSNK1A1 [cytosol] (Bos taurus)
Homologues of CSNK1A1 [cytosol] (Canis familiaris)
Homologues of CSNK1A1 [cytosol] (Drosophila melanogaster)
zeb2 [cytosol] (Xenopus tropicalis)
LOC100138998 [cytosol] (Bos taurus)
Ghost homologue of CSNK1A1 [cytosol] (Sus scrofa)
LOC613515 [cytosol] (Bos taurus)
CkIalpha [cytosol] (Drosophila melanogaster)
CSNK1A1 [cytosol] (Bos taurus)
CSNK1A1 [cytosol] (Canis familiaris)
CSNK1A1 [cytosol] (Dictyostelium discoideum)
CSNK1A1 [cytosol] (Gallus gallus)
Dmel\CG7094 [cytosol] (Drosophila melanogaster)
kin-19 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
NP_001258670.1
,
NP_001258671.1
,
NP_001020276.1
,
NP_001883.4
ZINC - World Drugs
KC1A_HUMAN
OpenTargets
ENSG00000113712
ZINC - FDA approved
KC1A_HUMAN
ZINC - Substances
KC1A_HUMAN
ZINC - Biogenic
KC1A_HUMAN
ZINC target
P48729
PRO
P48729
PDB
5FQD
,
6GZD
ZINC - Investigational
KC1A_HUMAN
IntEnz
2.7.11.1
HPA
ENSG00000113712-CSNK1A1
GeneCards
P48729
Ensembl
ENSP00000367074
,
ENSG00000113712
,
ENST00000657001
,
ENSP00000261798
,
ENSP00000499757
,
ENST00000261798
,
ENST00000377843
ZINC - Predictions - Purchasable
KC1A_HUMAN
Interactors (20)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6ZRV2 FA83H
0.752
10
UniProt:A6ND36 FA83G
0.722
12
UniProt:Q5T0W9 FA83B
0.664
7
UniProt:Q9H4H8 FA83D
0.649
5
UniProt:O15169 AXIN1
11
AXIN1 Y346* [cytosol]
(R-HSA-4839753)
AXIN1 L396M [cytosol]
(R-HSA-5251503)
AXIN1 E406* [cytosol]
(R-HSA-5251500)
AXIN1 W247* [cytosol]
(R-HSA-5251512)
AXIN1 P354L [cytosol]
(R-HSA-5251511)
AXIN1 P255S [cytosol]
(R-HSA-5251505)
ub-AXIN1 [cytosol]
(R-HSA-4641133)
AXIN1 [cytosol]
(R-HSA-195249)
p-T519,S524,S531-AXIN1 [cytosol]
(R-HSA-206040)
RibC-AXIN1 [cytosol]
(R-HSA-3640841)
Ub-RibC-AXIN1 [cytosol]
(R-HSA-3640864)
0.643
4
UniProt:Q96SW2 CRBN
1
CRBN [cytosol]
(R-HSA-8863300)
0.641
3
UniProt:Q9BQN1 FA83C
0.61
6
UniProt:Q13546 RIPK1
14
PolyUb-RIPK1 [cytosol]
(R-HSA-6783197)
K48polyUb-RIPK1 [cytosol]
(R-HSA-6783308)
RIPK1 D324N [cytosol]
(R-HSA-9693930)
RIPK1 D324Y [cytosol]
(R-HSA-9693931)
RIPK1 D324V [cytosol]
(R-HSA-9693927)
RIPK1 D324H [cytosol]
(R-HSA-9693922)
RIPK1 [plasma membrane]
(R-HSA-937073)
K63pUb-K377-RIP1 [cytosol]
(R-HSA-5212672)
RIPK1(1-324) [cytosol]
(R-HSA-5212664)
RIPK1(325-671) [cytosol]
(R-HSA-5212671)
p-S166-RIPK1 [cytosol]
(R-HSA-5218872)
K63polyUb-RIPK1 [cytosol]
(R-HSA-937021)
RIPK1 [endosome membrane]
(R-HSA-450326)
RIPK1 [cytosol]
(R-HSA-168651)
0.602
5
UniProt:O15151 MDM4
5
PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm]
(R-HSA-6804938)
PolyUb-MDM4 [nucleoplasm]
(R-HSA-6782502)
p-S346,S367,S403-MDM4 [nucleoplasm]
(R-HSA-349441)
p-S403-MDM4 [nucleoplasm]
(R-HSA-349461)
MDM4 [nucleoplasm]
(R-HSA-349430)
0.589
2
UniProt:Q63629 Q63629
0.544
2
UniProt:Q2M2I3 FA83E
0.537
6
UniProt:Q8NEG4 FA83F
0.537
7
UniProt:O15027 SEC16A
1
SEC16A [cytosol]
(R-HSA-5685728)
0.527
2
UniProt:Q00987 MDM2
11
SUMO1-K182-MDM2 [nucleoplasm]
(R-HSA-3000408)
PolyUb-MDM2 [nucleoplasm]
(R-HSA-6782472)
MDM2 [plasma membrane]
(R-HSA-416843)
MDM2 [endocytic vesicle membrane]
(R-HSA-416849)
p-S166,S188,T218-MDM2 [nucleoplasm]
(R-HSA-6792862)
PolyUb,p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6795669)
p-5S,T-MDM2 [nucleoplasm]
(R-HSA-6804954)
MDM2 [nucleoplasm]
(R-HSA-69486)
MDM2 [cytosol]
(R-HSA-198644)
p-S166,S188-MDM2 [cytosol]
(R-HSA-198638)
p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6793669)
0.524
3
UniProt:Q9UDY8 MALT1
1
MALT1 [cytosol]
(R-HSA-202461)
0.499
7
UniProt:Q9BXL7 CARD11
5
CARD11 [plasma membrane]
(R-HSA-2685592)
p-S559,S644,S652-CARD11 [plasma membrane]
(R-HSA-1168564)
p-S552,S645-CARD11 [cytosol]
(R-HSA-2685625)
CARD11 [cytosol]
(R-HSA-202161)
p-S552-CARD11 [cytosol]
(R-HSA-202438)
0.499
5
UniProt:P26583 HMGB2
1
HMGB2 [nucleoplasm]
(R-HSA-266211)
0.488
2
UniProt:P09429 HMGB1
5
HMGB1 [extracellular region]
(R-HSA-879382)
HC23,45-HMGB1 [extracellular region]
(R-HSA-6797422)
HMGB1 [nucleoplasm]
(R-HSA-266221)
HMGB1 [secretory granule lumen]
(R-HSA-6803337)
HMGB1 [ficolin-1-rich granule lumen]
(R-HSA-6803291)
0.488
2
UniProt:P18754 RCC1
2
RCC1 [nucleoplasm]
(R-HSA-180690)
RCC1 [chromosome]
(R-HSA-9668547)
0.488
3
UniProt:Q96A00 PPP1R14A
2
p-T38-PPP1R14A [cytosol]
(R-HSA-5671764)
PPP1R14A [cytosol]
(R-HSA-5671761)
0.488
2
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