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CANX [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-195906
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
calnexin
Locations in the PathwayBrowser for interactor UniProt:Q9P0L0 VAPA
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Influenza Infection (Homo sapiens)
Virus Assembly and Release (Homo sapiens)
Assembly of Viral Components at the Budding Site (Homo sapiens)
Glycosylation and Folding of HA (Homo sapiens)
CANX [endoplasmic reticulum lumen] (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of spike protein (Homo sapiens)
Trimmed spike protein binds to calnexin (Homo sapiens)
CANX [endoplasmic reticulum lumen] (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Late SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of spike protein (Homo sapiens)
Trimmed spike protein binds to calnexin (Homo sapiens)
CANX [endoplasmic reticulum lumen] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Dissociation of CANX from nonameric complex (Homo sapiens)
CANX [endoplasmic reticulum lumen] (Homo sapiens)
Interaction of invariant chain trimer and MHC II alpha beta dimer (Homo sapiens)
CANX [endoplasmic reticulum lumen] (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-12 family signaling (Homo sapiens)
Interleukin-27 signaling (Homo sapiens)
CANX binds EBI3 (Homo sapiens)
CANX [endoplasmic reticulum lumen] (Homo sapiens)
CANX dissociates from IL27:EBI3 (Homo sapiens)
CANX [endoplasmic reticulum lumen] (Homo sapiens)
Interleukin-35 Signalling (Homo sapiens)
CANX dissociates from IL12A:EBI3 (Homo sapiens)
CANX [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P27824 CANX
Gene Names
CANX
Chain
signal peptide:1-20, chain:21-592
Reference Genes
BioGPS Gene:821 CANX
COSMIC (genes):CANX CANX
CTD Gene:821 CANX
dbSNP Gene:821 CANX
ENSEMBL:ENSG00000127022 CANX
ENSEMBL_homo_sapiens_GENE:ENSG00000127022.16 CANX
ENSEMBL_homo_sapiens_GENE:ENSG00000283777.2 CANX
HGNC:1473 CANX
KEGG Gene (Homo sapiens):821 CANX
Monarch:821 CANX
NCBI Gene:821 CANX
OMIM:114217 CANX
UCSC:P27824 CANX
Reference Transcript
RefSeq:NM_001746.3 CANX
RefSeq:XM_011534665.2 CANX
RefSeq:NM_001024649.1 CANX
Other Identifiers
11727421_a_at
11727422_s_at
11727423_a_at
11727424_s_at
11727425_s_at
11727426_a_at
11741127_s_at
11745457_a_at
16656823
16656825
16656827
16656829
16656831
16656833
16993397
18670177
18670178
18670179
18670180
18670181
18670182
18670183
18670184
18670185
18670186
18670187
18670189
18670190
18670192
18670193
18670194
18670195
18670196
18670197
18670199
18670200
18670201
18670202
200068_PM_s_at
200068_s_at
208852_PM_s_at
208852_s_at
208853_PM_s_at
208853_s_at
238034_PM_at
238034_at
238138_PM_at
238138_at
2844192
2844193
2844204
2844205
2844206
2844207
2844209
2844212
2844213
2844214
2844215
2844217
2844219
2844222
2844226
2844227
2844228
2844229
2844230
2844231
2844233
2844235
2844238
2844241
2844242
2844243
2844244
2844245
2844246
2844247
2844248
2844249
2844250
2844251
2844253
2844255
2844263
2844411
2844412
2844413
2844414
2844415
2844416
2844417
40125_at
53131_at
57826_at
7892514
7892972
7893103
7893270
7893272
7893345
7893632
7893641
7893642
7893880
7894074
7894674
7894687
7894725
7894878
7895017
7895188
7895276
7895283
7895334
7895475
7895547
7895693
7896020
7896050
7896136
7896308
7896387
7896430
7896644
8110522
821
83775_at
A_23_P147185
A_24_P345993
A_33_P3325131
GE57598
GE85806
GO:0003723
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005635
GO:0005739
GO:0005783
GO:0005788
GO:0005789
GO:0006457
GO:0009306
GO:0016020
GO:0016192
GO:0019082
GO:0030163
GO:0030246
GO:0030433
GO:0031410
GO:0031965
GO:0031966
GO:0033162
GO:0034975
GO:0043226
GO:0044233
GO:0044322
GO:0046872
GO:0048488
GO:0051082
GO:0070062
GO:0072583
GO:0098553
GO:0098793
HMNXSV003013314
Hs.155560.0.S2_3p_a_at
Hs.157515.0.A1_3p_at
Hs.43679.0.A1_3p_at
ILMN_1762825
ILMN_2401057
L10284_at
PH_hs_0009368
TC05001050.hg
g179831_3p_a_at
g306480_3p_a_at
Participates
as an input of
Interaction of invariant chain trimer and MHC II alpha beta dimer (Homo sapiens)
CANX binds EBI3 (Homo sapiens)
as an output of
Dissociation of CANX from nonameric complex (Homo sapiens)
CANX dissociates from IL12A:EBI3 (Homo sapiens)
CANX dissociates from IL27:EBI3 (Homo sapiens)
as a component of
alpha beta dimer:Ii trimer:calnexin [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
CANX:EBI3 [endoplasmic reticulum lumen] (Homo sapiens)
CALR:CANX [endoplasmic reticulum lumen] (Homo sapiens)
as a member of
CALR,CANX [endoplasmic reticulum lumen] (Homo sapiens)
This entity regulates
Positively
Glycosylation and Folding of HA
(Homo sapiens)
Other forms of this molecule
CANX [lumenal side of endoplasmic reticulum membrane]
Inferred To
CANX [endoplasmic reticulum lumen]
(Bos taurus)
CANX [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
CANX [endoplasmic reticulum lumen]
(Canis familiaris)
CANX [endoplasmic reticulum lumen]
(Gallus gallus)
CANX [endoplasmic reticulum lumen]
(Mus musculus)
CANX [endoplasmic reticulum lumen]
(Rattus norvegicus)
CANX [endoplasmic reticulum lumen]
(Saccharomyces cerevisiae)
CANX [endoplasmic reticulum lumen]
(Schizosaccharomyces pombe)
CANX [endoplasmic reticulum lumen]
(Sus scrofa)
Cnx99A [endoplasmic reticulum lumen]
(Drosophila melanogaster)
canx [endoplasmic reticulum lumen]
(Danio rerio)
canx [endoplasmic reticulum lumen]
(Xenopus tropicalis)
cnxA [endoplasmic reticulum lumen]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001019820.1
,
XP_011532967.1
,
NP_001737.1
OpenTargets
ENSG00000127022
HPA
ENSG00000127022-CANX
GeneCards
P27824
Ensembl
ENST00000681476
,
ENST00000680042
,
ENSP00000424745
,
ENSP00000505526
,
ENSP00000505129
,
ENSP00000421434
,
ENST00000638425
,
ENSP00000424063
,
ENST00000680618
,
ENST00000452673
,
ENSP00000505013
,
ENSP00000506003
,
ENSP00000505202
,
ENSG00000283777
,
ENST00000681712
,
ENST00000680006
,
ENST00000681733
,
ENST00000681072
,
ENSP00000491760
,
ENST00000681674
,
ENST00000506654
,
ENST00000680092
,
ENST00000680013
,
ENST00000681168
,
ENSG00000127022
,
ENST00000639938
,
ENSP00000426555
,
ENST00000638706
,
ENSP00000492372
,
ENSP00000506568
,
ENST00000504734
,
ENSP00000506583
,
ENSP00000506021
,
ENST00000502296
,
ENSP00000506061
,
ENSP00000506509
,
ENST00000513246
,
ENST00000247461
,
ENSP00000506078
,
ENSP00000505960
,
ENSP00000492868
,
ENST00000680827
,
ENSP00000391646
,
ENSP00000247461
,
ENST00000509563
,
ENST00000681903
,
ENSP00000506051
,
ENSP00000421813
PRO
P27824
Pharos - Targets
P27824
HMDB Protein
HMDBP07535
Interactors (165)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.888
27
UniProt:P43307 SSR1
1
SSR1 [endoplasmic reticulum membrane]
(R-HSA-444588)
0.773
7
UniProt:Q9H5K3 POMK
1
POMK [endoplasmic reticulum membrane]
(R-HSA-8879120)
0.725
5
UniProt:P61619 SEC61A1
2
SEC61A1 [endoplasmic reticulum membrane]
(R-HSA-444591)
SEC61A1 [phagocytic vesicle membrane]
(R-HSA-1236813)
0.69
5
UniProt:Q8N766 EMC1
0.671
5
UniProt:P04844 RPN2
1
RPN2 [endoplasmic reticulum membrane]
(R-HSA-264937)
0.671
5
UniProt:Q7LFX5 CHST15
1
CHST15 [Golgi membrane]
(R-HSA-1971543)
0.669
3
UniProt:Q8TCJ2 STT3B
0.644
5
UniProt:Q9BTY2 FUCA2
4
FUCA2 [extracellular region]
(R-HSA-6806227)
FUCA2 [azurophil granule lumen]
(R-HSA-6798772)
p-FUCA2 [endoplasmic reticulum lumen]
(R-HSA-8957005)
FUCA2 [endoplasmic reticulum lumen]
(R-HSA-8956727)
0.643
3
UniProt:Q9H741 SPRNG
0.643
3
UniProt:Q8NBL1 POGLUT1
1
POGLUT1 [endoplasmic reticulum lumen]
(R-HSA-1464796)
0.643
5
UniProt:O94905 ERLIN2
3
ERLIN2 [endoplasmic reticulum membrane]
(R-HSA-8866520)
EML4(1-186)insVSLKRRIELTVEYPWRCGALSPTSNCRTG-p-8Y-FGFR1(1-822) [plasma membrane]
(R-HSA-8853122)
EML4(1-186)insVSLKRRIELTVEYPWRCGALSPTSNCRTG-FGFR1(1-822) [plasma membrane]
(R-HSA-8853148)
0.643
3
UniProt:Q9UIQ6 LNPEP
3
LNPEP [cytoplasmic vesicle membrane]
(R-HSA-1445121)
LNPEP [early endosome lumen]
(R-HSA-1236834)
LNPEP [cytosol]
(R-HSA-983098)
0.643
3
UniProt:Q14703 MBTPS1
4
MBTPS1 [Golgi membrane]
(R-HSA-381108)
MBTPS1 [endoplasmic reticulum membrane]
(R-HSA-6797334)
p-MBTPS1 [endoplasmic reticulum lumen]
(R-HSA-8956924)
MBTPS1 [endoplasmic reticulum lumen]
(R-HSA-8956733)
0.643
3
UniProt:P54709 ATP1B3
1
ATP1B3 [plasma membrane]
(R-HSA-375073)
0.643
3
UniProt:P16615 ATP2A2
2
ATP2A2 [platelet dense tubular network membrane]
(R-HSA-427903)
ATP2A2 [endoplasmic reticulum membrane]
(R-HSA-391962)
0.643
3
UniProt:Q8NCH0 CHST14
9
CHST14 K69* [Golgi membrane]
(R-HSA-3636891)
CHST14 R135G [Golgi membrane]
(R-HSA-3636924)
CHST14 C289S [Golgi membrane]
(R-HSA-3636925)
CHST14 V49* [Golgi membrane]
(R-HSA-3636926)
CHST14 R213P [Golgi membrane]
(R-HSA-3636894)
CHST14 Y293C [Golgi membrane]
(R-HSA-3636927)
CHST14 P281L [Golgi membrane]
(R-HSA-3636880)
CHST14 L137Q [Golgi membrane]
(R-HSA-5649488)
CHST14 [Golgi membrane]
(R-HSA-1971536)
0.643
3
UniProt:P04578 env
7
Surface protein gp120 (P04578) [cytosol]
(R-HIV-189269)
Transmembrane protein gp41 (P04578) [cytosol]
(R-HIV-189359)
Glycosylated Envelope glycoprotein gp160 [Golgi membrane]
(R-HIV-3149443)
Envelope glycoprotein gp160 [endoplasmic reticulum membrane]
(R-HIV-189343)
Transmembrane protein gp41 [viral envelope]
(R-HIV-171195)
ENV [viral envelope]
(R-HIV-173439)
Surface protein gp120 [viral envelope]
(R-HIV-171211)
0.623
3
UniProt:Q9H3N1 TMX1
0.615
6
UniProt:P35610 SOAT1
1
SOAT1 [endoplasmic reticulum membrane]
(R-HSA-8876490)
0.615
4
UniProt:O00115 DNASE2
2
DNASE2 [Golgi lumen]
(R-HSA-434322)
DNASE2 [lysosomal lumen]
(R-HSA-429822)
0.589
2
UniProt:O95477 ABCA1
11
ABCA1 W590S [plasma membrane]
(R-HSA-5682201)
ABCA1 N935S [plasma membrane]
(R-HSA-5682200)
ABCA1 C1417R [plasma membrane]
(R-HSA-5682190)
ABCA1 S1446L [plasma membrane]
(R-HSA-5682195)
ABCA1 R587W [plasma membrane]
(R-HSA-5682197)
ABCA1 [plasma membrane]
(R-HSA-194209)
4xPALM-C-p-2S-ABCA1 [plasma membrane]
(R-HSA-5682069)
4xPALM-C-ABCA1 [endoplasmic reticulum membrane]
(R-HSA-5682085)
4xPALM-C-ABCA1 [plasma membrane]
(R-HSA-5682091)
ABCA1 [endoplasmic reticulum membrane]
(R-HSA-5682105)
ABCA1 Q537R [plasma membrane]
(R-HSA-5682199)
0.576
8
UniProt:Q9NZ01 TECR
1
TECR [endoplasmic reticulum membrane]
(R-HSA-548663)
0.569
3
UniProt:P08069 IGF1R
3
IGF1R(741-1367) [plasma membrane]
(R-HSA-2404180)
IGF1R(31-736) [plasma membrane]
(R-HSA-2404169)
p-Y1161,Y1165,Y1166-IGF1R(741-1367) [plasma membrane]
(R-HSA-2404172)
0.569
3
UniProt:P35606 COPB2
4
COPB2 [endoplasmic reticulum membrane]
(R-HSA-6810957)
COPB2 [Golgi membrane]
(R-HSA-6808739)
COPB2 [transport vesicle]
(R-HSA-6808741)
COPB2 [cytosol]
(R-HSA-199972)
0.569
4
UniProt:P46977 STT3A
1
STT3A [endoplasmic reticulum membrane]
(R-HSA-265023)
0.569
3
UniProt:P39656 DDOST
3
DDOST [azurophil granule membrane]
(R-HSA-6799145)
DDOST [plasma membrane]
(R-HSA-879386)
DDOST [endoplasmic reticulum membrane]
(R-HSA-264963)
0.569
5
UniProt:Q96AG4 LRC59
0.569
4
UniProt:O14967 CLGN
0.569
3
UniProt:O00264 PGRMC1
2
PGRMC1 [plasma membrane]
(R-HSA-6806314)
PGRMC1 [specific granule membrane]
(R-HSA-6799648)
0.569
4
UniProt:Q9H2J7 SLC6A15
1
SLC6A15 [plasma membrane]
(R-HSA-352060)
0.569
3
UniProt:Q14739 LBR
4
LBR [nuclear envelope]
(R-HSA-194637)
p-S71,S86-LBR [nuclear envelope]
(R-HSA-9624811)
LBR [endoplasmic reticulum membrane]
(R-HSA-9714334)
LBR [endosome membrane]
(R-HSA-9715094)
0.569
4
UniProt:Q9Y4L1 HYOU1
3
HYOU1 [extracellular region]
(R-HSA-3221939)
HYOU1 [endocytic vesicle lumen]
(R-HSA-3221924)
HYOU1 [endoplasmic reticulum lumen]
(R-HSA-535542)
0.569
4
UniProt:P04843 RPN1
1
RPN1 [endoplasmic reticulum membrane]
(R-HSA-264994)
0.569
4
UniProt:Q8NFQ8 TOIP2
0.569
3
UniProt:Q96GF1 RNF185
1
RNF185 [endoplasmic reticulum membrane]
(R-HSA-8861819)
0.569
3
UniProt:Q07065 CKAP4
7
CKAP4 [endoplasmic reticulum lumen]
(R-HSA-8956737)
p-CKAP4 [endoplasmic reticulum lumen]
(R-HSA-8956926)
CKAP4 [azurophil granule membrane]
(R-HSA-6799559)
CKAP4 [plasma membrane]
(R-HSA-5686306)
CKAP4 [specific granule membrane]
(R-HSA-6799552)
PALM-C100-CKAP4 [plasma membrane]
(R-HSA-5686280)
PALM-C100-CKAP4 [lamellar body]
(R-HSA-5686285)
0.569
3
UniProt:Q9P0L0 VAPA
4
VAPA [endoplasmic reticulum membrane]
(R-HSA-429677)
VAPA [azurophil granule membrane]
(R-HSA-6799364)
VAPA [plasma membrane]
(R-HSA-6806269)
VAPA [cytosol]
(R-HSA-9609920)
0.569
5
UniProt:O75787 ATP6AP2
3
ATP6AP2 [plasma membrane]
(R-HSA-2022356)
ATP6AP2 [tertiary granule membrane]
(R-HSA-6799717)
ATP6AP2 [ficolin-1-rich granule membrane]
(R-HSA-6800921)
0.569
4
UniProt:P05556 ITGB1
2
ITGB1 [endosome membrane]
(R-HSA-9611157)
ITGB1 [plasma membrane]
(R-HSA-57596)
0.569
3
UniProt:P55011 SLC12A2
1
SLC12A2 [plasma membrane]
(R-HSA-426146)
0.569
4
UniProt:Q9UBF2 COPG2
4
COPG2 [endoplasmic reticulum membrane]
(R-HSA-6810962)
COPG2 [Golgi membrane]
(R-HSA-6808751)
COPG2 [transport vesicle]
(R-HSA-6808753)
COPG2 [cytosol]
(R-HSA-6807747)
0.569
3
UniProt:P04626 ERBB2
20
ERBB2 G309E [plasma membrane]
(R-HSA-9665342)
ERBB2 G309A [plasma membrane]
(R-HSA-9665349)
ERBB2 S310F [plasma membrane]
(R-HSA-9665350)
ERBB2 S310Y [plasma membrane]
(R-HSA-9665344)
p-6Y-ERBB2 G309A [plasma membrane]
(R-HSA-9665381)
p-6Y-ERBB2 G309E [plasma membrane]
(R-HSA-9665382)
p-6Y-ERBB2 S310F [plasma membrane]
(R-HSA-9665379)
p-6Y-ERBB2 S310Y [plasma membrane]
(R-HSA-9665385)
p-Y-ERBB2 L755P [plasma membrane]
(R-HSA-9654268)
p-Y-ERBB2 I767M [plasma membrane]
(R-HSA-9654303)
p-Y-ERBB2 T798I [plasma membrane]
(R-HSA-9654618)
p-Y-ERBB2 Y772_A775dup [plasma membrane]
(R-HSA-9665652)
p-Y-ERBB2 T862A [plasma membrane]
(R-HSA-9654695)
p-Y-ERBB2 T798M [plasma membrane]
(R-HSA-9654615)
p-Y-ERBB2 H878Y [plasma membrane]
(R-HSA-9654833)
p-Y-ERBB2 V777L [plasma membrane]
(R-HSA-9654401)
p-Y-ERBB2 L755S [plasma membrane]
(R-HSA-9654194)
p-Y-ERBB2 V777E [plasma membrane]
(R-HSA-9654397)
p-Y-ERBB2 V777M [plasma membrane]
(R-HSA-9654398)
p-Y-ERBB2 L755M [plasma membrane]
(R-HSA-9654191)
0.569
3
UniProt:P35613 BSG
2
BSG [Golgi membrane]
(R-HSA-204478)
BSG [plasma membrane]
(R-HSA-197673)
0.569
4
UniProt:Q15904 ATP6AP1
2
ATP6AP1 [endoplasmic reticulum membrane]
(R-HSA-9714332)
ATP6AP1 [endosome membrane]
(R-HSA-5215981)
0.569
4
UniProt:Q9NZC7 WWOX
1
WWOX [cytosol]
(R-HSA-1253335)
0.569
3
UniProt:O15173 PGRMC2
4
PGRMC2 [nuclear envelope]
(R-HSA-9707674)
PGRMC2 [nucleoplasm]
(R-HSA-9707859)
PGRMC2 [endoplasmic reticulum membrane]
(R-HSA-9714349)
PGRMC2 [endosome membrane]
(R-HSA-9715090)
0.569
4
UniProt:Q9Y5M8 SRPRB
1
SRPRB [endoplasmic reticulum membrane]
(R-HSA-265002)
0.569
4
UniProt:Q921T2
1
Tor1aip1 [cytosol]
(R-MMU-9715083)
0.564
2
UniProt:P00387 CYB5R3
3
MyrG-CYB5R3(2-301) [mitochondrial outer membrane]
(R-HSA-198771)
CYB5R3(27-301) [extracellular region]
(R-HSA-6806205)
CYB5R3(27-301) [azurophil granule lumen]
(R-HSA-6799217)
0.564
2
UniProt:Q8NBM8 PCYOX1L
2
PCYOX1L [extracellular region]
(R-HSA-8862953)
PCYOX1L [platelet alpha granule lumen]
(R-HSA-8862980)
0.527
2
UniProt:Q9Y2A9 B3GNT3
1
B3GNT3 [Golgi membrane]
(R-HSA-916819)
0.527
3
UniProt:P36897 TGFBR1
13
Ub-TGFBR1 [plasma membrane]
(R-HSA-8869461)
p-4S,T185,T186-TGFBR1 W242* [plasma membrane]
(R-HSA-3656504)
p-4S,T185,T186-TGFBR1 P327Qfs*8 [plasma membrane]
(R-HSA-3656505)
p-4S,T185,T186-TGFBR1 L354Nfs*4 [plasma membrane]
(R-HSA-3656506)
p-4S,T185,T186-TGFBR1 R414* [plasma membrane]
(R-HSA-3656508)
p-4S,T185,T186-TGFBR1 D269_Q324del [plasma membrane]
(R-HSA-3656509)
TGFBR1 G52R [plasma membrane]
(R-HSA-3656368)
TGFBR1 C41Y [plasma membrane]
(R-HSA-3656328)
TGFBR1 N45S [plasma membrane]
(R-HSA-3656348)
TGFBR1 P83L [plasma membrane]
(R-HSA-3656341)
TGFBR1 P83S [plasma membrane]
(R-HSA-3656326)
TGFBR1 [plasma membrane]
(R-HSA-170839)
p-4S,T185,T186-TGFBR1 [plasma membrane]
(R-HSA-170849)
0.527
2
UniProt:Q15165 PON2
1
PON2 [extracellular region]
(R-HSA-8932636)
0.527
2
UniProt:O60512 B4GALT3
1
B4GALT3 [Golgi membrane]
(R-HSA-975922)
0.527
2
UniProt:P42892 ECE1
1
ECE1 [plasma membrane]
(R-HSA-8876866)
0.527
2
UniProt:P06280 GLA
3
GLA [extracellular region]
(R-HSA-6806179)
GLA [azurophil granule lumen]
(R-HSA-6798777)
GLA [lysosomal lumen]
(R-HSA-1605763)
0.527
2
UniProt:Q8WTV0 SCARB1
0.527
2
UniProt:Q6UWY0 ARSK
2
OxA-ARSK [endoplasmic reticulum lumen]
(R-HSA-1614364)
ARSK [endoplasmic reticulum lumen]
(R-HSA-1609684)
0.527
3
UniProt:Q9UNL2 SSR3
1
SSR3 [endoplasmic reticulum membrane]
(R-HSA-264973)
0.527
2
UniProt:Q9H1A3 METL9
0.527
2
UniProt:P45880 VDAC2
6
p-S65-Ub:VDAC2 [mitochondrial outer membrane]
(R-HSA-9834982)
K63polyUb-VDAC2 [mitochondrial outer membrane]
(R-HSA-9843314)
K48polyUb-VDAC2 [mitochondrial outer membrane]
(R-HSA-9843321)
Ub-VDAC2 [mitochondrial outer membrane]
(R-HSA-9835025)
VDAC2 [mitochondrial outer membrane]
(R-HSA-5696880)
PolyUb-VDAC2 [mitochondrial outer membrane]
(R-HSA-6783185)
0.527
2
UniProt:Q14982 OPCML
2
cleaved GPI-OPCML [extracellular region]
(R-HSA-8941075)
GPI-OPCML [plasma membrane]
(R-HSA-8940828)
0.527
2
UniProt:Q9Y320 TMX2
0.527
3
UniProt:P08195 SLC3A2
1
SLC3A2 [plasma membrane]
(R-HSA-352179)
0.527
2
UniProt:P40126 DCT
1
DCT [melanosome membrane]
(R-HSA-5662685)
0.527
3
UniProt:Q8IWF2 FXRD2
0.527
3
UniProt:Q9NV96 TMEM30A
3
TMEM30A [specific granule membrane]
(R-HSA-6799526)
TMEM30A [plasma membrane]
(R-HSA-6806278)
TMEM30A [azurophil granule membrane]
(R-HSA-6799504)
0.527
2
UniProt:Q96EG1 ARSG
2
OxA-ARSG [endoplasmic reticulum lumen]
(R-HSA-1614304)
ARSG [endoplasmic reticulum lumen]
(R-HSA-1614361)
0.527
2
UniProt:Q9Y2B1 RXLT1
0.527
2
UniProt:P54802 NAGLU
5
NAGLU R674C [lysosomal lumen]
(R-HSA-2219558)
NAGLU R674H [lysosomal lumen]
(R-HSA-2219557)
NAGLU R626* [lysosomal lumen]
(R-HSA-2219568)
NAGLU R297* [lysosomal lumen]
(R-HSA-2219553)
NAGLU(59-743) [lysosomal lumen]
(R-HSA-1678772)
0.527
2
UniProt:P56704 WNT3A
10
N4GlycoAsn-PalmS WNT3A [plasma membrane]
(R-HSA-3247807)
N4GlycoAsn-PalmS WNT3A [extracellular region]
(R-HSA-3247784)
N4GlycoAsn-PalmS WNT3A [Golgi lumen]
(R-HSA-3247832)
N4GlycoAsn-PalmS WNT3A [endoplasmic reticulum lumen]
(R-HSA-3238344)
N4GlycoAsn-WNT3A [endoplasmic reticulum lumen]
(R-HSA-3238231)
WNT3A [endoplasmic reticulum lumen]
(R-HSA-3238292)
N4GlycoAsn-PalmS WNT3A [early endosome membrane]
(R-HSA-5368483)
N4GlycoAsn-PalmS WNT3A [endocytic vesicle membrane]
(R-HSA-3781944)
N4GlycoAsn-PalmS WNT3A [extracellular exosome]
(R-HSA-3781968)
WNT3A [extracellular region]
(R-HSA-201710)
0.527
3
UniProt:Q9Y5X9 LIPG
1
LIPG [extracellular region]
(R-HSA-6789318)
0.527
2
UniProt:Q86YC3 LRC33
0.527
2
UniProt:Q6PK18 OGFD3
0.527
3
UniProt:Q8NE01 CNNM3
0.527
2
UniProt:Q8TCT7 SPPL2B
1
SPPL2B [plasma membrane]
(R-HSA-8863116)
0.527
2
UniProt:Q16880 UGT8
1
UGT8 [endoplasmic reticulum membrane]
(R-HSA-9844570)
0.527
2
UniProt:Q96MM7 HS6ST2
1
HS6ST2 [Golgi membrane]
(R-HSA-2076353)
0.527
2
UniProt:Q6UWB1 IL27RA
4
IL27RA [plasma membrane]
(R-HSA-448478)
p-Y611-IL27RA [plasma membrane]
(R-HSA-8950330)
sIL27RA [extracellular region]
(R-HSA-8950454)
sIL27RA [cytoplasm]
(R-HSA-8950653)
0.527
2
UniProt:P49286 MTNR1B
1
MTNR1B [plasma membrane]
(R-HSA-419349)
0.527
2
UniProt:Q9UKU6 TRHDE
0.527
2
UniProt:Q8N5K1 CISD2
0.527
2
UniProt:P18507 GABRG2
1
GABRG2 [plasma membrane]
(R-HSA-975350)
0.527
2
UniProt:Q17R55 F187B
0.527
2
UniProt:P04062 GBA1
2
Unfolded GBA [cytosol]
(R-HSA-6813790)
GBA1 [lysosomal membrane]
(R-HSA-1605775)
0.527
2
UniProt:Q99999 GAL3ST1
1
GAL3ST1 [Golgi membrane]
(R-HSA-1631586)
0.527
3
UniProt:P10909 CLU
4
CLU(23-449) [extracellular region]
(R-HSA-349732)
CLU(23-449) [platelet alpha granule lumen]
(R-HSA-349733)
CLU(228-449) [extracellular region]
(R-HSA-6810626)
CLU(23-227) [extracellular region]
(R-HSA-6810660)
0.527
2
UniProt:Q86T26 TM11B
0.527
2
UniProt:Q9UKJ8 ADAM21
1
ADAM21 [plasma membrane]
(R-HSA-1297340)
0.527
3
UniProt:P48039 MTNR1A
1
MTNR1A [plasma membrane]
(R-HSA-419316)
0.527
2
UniProt:O14656 TOR1A
1
TOR1A [cytosol]
(R-HSA-8862858)
0.527
3
UniProt:Q9C0B6 BRNP2
0.527
3
UniProt:Q16842 ST3GAL2
1
ST3GAL2 [Golgi membrane]
(R-HSA-981482)
0.527
2
UniProt:P11021 HSPA5
6
HSPA5 [extracellular region]
(R-HSA-351322)
HSPA5 [endoplasmic reticulum lumen]
(R-HSA-387190)
HSPA5 [endoplasmic reticulum membrane]
(R-HSA-351315)
HSPA5 [cytosol]
(R-HSA-5252115)
HSPA5 [nucleoplasm]
(R-HSA-5252042)
HSPA5 [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985498)
0.527
2
UniProt:P51172 SCNN1D
1
SCNN1D [plasma membrane]
(R-HSA-2671902)
0.527
2
UniProt:Q96JJ7 TMX3
2
TMX3 [plasma membrane]
(R-HSA-8848896)
TMX3 [platelet alpha granule membrane]
(R-HSA-8848889)
0.527
3
UniProt:Q92820 GGH
4
GGH [specific granule lumen]
(R-HSA-6799639)
GGH [tertiary granule lumen]
(R-HSA-6800911)
GGH [extracellular region]
(R-HSA-6799679)
GGH [azurophil granule lumen]
(R-HSA-6800950)
0.527
2
UniProt:Q92542 NCSTN
3
NCSTN [endosome membrane]
(R-HSA-9010085)
NCSTN [azurophil granule membrane]
(R-HSA-6799220)
NCSTN [plasma membrane]
(R-HSA-2534241)
0.527
2
UniProt:Q03518 TAP1
3
TAP1 [phagocytic vesicle membrane]
(R-HSA-1236845)
TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863953)
TAP1 [endoplasmic reticulum membrane]
(R-HSA-947474)
0.527
2
UniProt:Q86WK7 AMGO3
0.527
2
UniProt:Q7L1S5 CHST9
0.527
2
UniProt:O75477 ERLIN1
1
ERLIN1 [endoplasmic reticulum membrane]
(R-HSA-8866518)
0.527
2
UniProt:Q9GZX3 CHST6
9
CHST6 R211W [Golgi membrane]
(R-HSA-3656457)
CHST6 L276P [Golgi membrane]
(R-HSA-3656477)
CHST6 K174R [Golgi membrane]
(R-HSA-3656480)
CHST6 [Golgi membrane]
(R-HSA-1971537)
CHST6 C102G [Golgi membrane]
(R-HSA-3656470)
CHST6 L200R [Golgi membrane]
(R-HSA-3656454)
CHST6 D203E [Golgi membrane]
(R-HSA-3656437)
CHST6 E274K [Golgi membrane]
(R-HSA-3656420)
CHST6 Y110C [Golgi membrane]
(R-HSA-3656419)
0.527
2
UniProt:O75354 ENTPD6
1
ENTPD6 (77-484) [extracellular region]
(R-HSA-8851464)
0.527
2
UniProt:P15812 CD1E
0.527
2
UniProt:Q9HB40 RISC
0.527
2
UniProt:P29016 CD1B
1
CD1B [plasma membrane]
(R-HSA-197793)
0.527
3
UniProt:Q7KZN9 COX15
1
COX15 [mitochondrial inner membrane]
(R-HSA-2995350)
0.527
2
UniProt:Q4G148 GXLT1
0.527
3
UniProt:Q8IZF4 AGRG5
0.527
2
UniProt:Q13724 MOGS
3
MOGS F652L [endoplasmic reticulum membrane]
(R-HSA-4839779)
MOGS R486T [endoplasmic reticulum membrane]
(R-HSA-4839818)
MOGS [endoplasmic reticulum membrane]
(R-HSA-532676)
0.527
2
UniProt:Q13443 ADAM9
1
ADAM9 [plasma membrane]
(R-HSA-708336)
0.527
2
UniProt:Q9H4B8 DPEP3
0.527
2
UniProt:Q08380 LGALS3BP
2
LGALS3BP [extracellular region]
(R-HSA-8848882)
LGALS3BP [platelet dense granule lumen]
(R-HSA-8848916)
0.527
2
UniProt:Q8WXQ8 CBPA5
0.527
2
UniProt:P01019 AGT
7
AGT(36-41) [extracellular region]
(R-HSA-2022355)
AGT(35-41) [extracellular region]
(R-HSA-2022354)
AGT(34-40) [extracellular region]
(R-HSA-2022351)
AGT(34-42) [extracellular region]
(R-HSA-2022348)
AGT [extracellular region]
(R-HSA-1998759)
AGT(34-43) [extracellular region]
(R-HSA-2022346)
AGT(34-41) [extracellular region]
(R-HSA-374187)
0.527
2
UniProt:Q13444 ADAM15
1
ADAM15 [plasma membrane]
(R-HSA-708329)
0.527
2
UniProt:Q9H0U3 MAGT1
2
MAGT1 [azurophil granule membrane]
(R-HSA-6799208)
MAGT1 [plasma membrane]
(R-HSA-4836523)
0.527
2
UniProt:P30101 PDIA3
3
PDIA3 [phagocytic vesicle]
(R-HSA-1236870)
PDIA3 [recycling endosome membrane]
(R-HSA-8863849)
PDIA3 [endoplasmic reticulum lumen]
(R-HSA-901028)
0.527
2
UniProt:Q9H2A9 CHST8
1
CHST8 [Golgi membrane]
(R-HSA-6786024)
0.527
3
UniProt:Q6PIU2 NCEH1
1
NCEH1 [endoplasmic reticulum membrane]
(R-HSA-6813685)
0.527
2
UniProt:Q16288 NTRK3
6
NTRK3(32-495) [plasma membrane]
(R-HSA-9603541)
NTRK3(642-839) [cytosol]
(R-HSA-9603540)
NTRK3(496-641) [mitochondrial outer membrane]
(R-HSA-9603557)
NTRK3(496-641) [cytosol]
(R-HSA-9603542)
NTRK3 [plasma membrane]
(R-HSA-6798240)
p-5Y-NTRK3 [plasma membrane]
(R-HSA-9034718)
0.527
2
UniProt:P21796 VDAC1
7
PolyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-6783079)
VDAC1 [mitochondrial intermembrane space]
(R-HSA-1267960)
VDAC1 [mitochondrial outer membrane]
(R-HSA-1267988)
Ub-VDAC1 [mitochondrial outer membrane]
(R-HSA-9834989)
K48polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-5205624)
K63polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-9834037)
p-S65-Ub:VDAC1 [mitochondrial outer membrane]
(R-HSA-9834991)
0.527
3
UniProt:Q9NPC4 A4GALT
1
A4GALT [Golgi membrane]
(R-HSA-9846476)
0.527
3
UniProt:Q9Y2C2 UST
1
UST [Golgi membrane]
(R-HSA-2022058)
0.527
3
UniProt:Q9UHC6-1 CNTNAP2
0.499
2
UniProt:P41143 OPRD1
1
OPRD1 [plasma membrane]
(R-HSA-374265)
0.499
2
UniProt:P11607
2
ATP2A2 [platelet dense tubular network membrane]
(R-SSC-427903)
ATP2A2 [endoplasmic reticulum membrane]
(R-SSC-391962)
0.499
2
UniProt:P0C739 BNL2A
0.491
2
UniProt:O75976 CPD
3
CPD [Golgi membrane]
(R-HSA-432675)
CPD [cytoplasmic vesicle membrane]
(R-HSA-432671)
CPD [plasma membrane]
(R-HSA-9715182)
0.483
2
UniProt:Q86Y07 VRK2
2
VRK2 [mitochondrial outer membrane]
(R-HSA-9715102)
VRK2 [endoplasmic reticulum membrane]
(R-HSA-9714457)
0.483
3
UniProt:P51648 ALDH3A2
1
ALDH3A2 [cytosol]
(R-HSA-9715204)
0.483
3
UniProt:Q9HCU5 PREB
1
PREB [endoplasmic reticulum membrane]
(R-HSA-203984)
0.483
3
UniProt:O14579 COPE
4
COPE [endoplasmic reticulum membrane]
(R-HSA-6810959)
COPE [Golgi membrane]
(R-HSA-6808743)
COPE [transport vesicle]
(R-HSA-6808745)
COPE [cytosol]
(R-HSA-199969)
0.483
3
UniProt:P52298 NCBP2
2
NCBP2 [nucleoplasm]
(R-HSA-51463)
NCBP2 [cytosol]
(R-HSA-162458)
0.483
2
UniProt:O95292 VAPB
2
VAPB [endoplasmic reticulum membrane]
(R-HSA-429718)
VAPB [Golgi membrane]
(R-HSA-9715115)
0.483
3
UniProt:O95573 ACSL3
2
ACSL3 [mitochondrial outer membrane]
(R-HSA-9632656)
ACSL3 [endoplasmic reticulum membrane]
(R-HSA-548787)
0.483
3
UniProt:Q9P0I2 EMC3
1
EMC3 [endoplasmic reticulum membrane]
(R-HSA-9714347)
0.483
3
UniProt:Q9H8Y8 GORASP2
2
GORASP2 [Golgi membrane]
(R-HSA-2422385)
p-T222,T225-GORASP2 [Golgi membrane]
(R-HSA-2422965)
0.483
2
UniProt:O43865 AHCYL1
1
AHCYL1 [endoplasmic reticulum membrane]
(R-HSA-5215973)
0.483
2
UniProt:Q6ZNB6 NFXL1
0.483
2
UniProt:P30530 AXL
2
p-Y779,Y821-AXL [plasma membrane]
(R-HSA-5357460)
AXL [plasma membrane]
(R-HSA-197705)
0.483
2
UniProt:Q9BTX1 NDC1
1
NDC1 [nuclear envelope]
(R-HSA-6805183)
0.483
3
UniProt:O43402 EMC8
0.483
2
UniProt:Q96A57 TM230
0.483
2
UniProt:Q9Y679 AUP1
0.483
2
UniProt:Q6NUS6 TCTN3
1
TCTN3 [ciliary membrane]
(R-HSA-5626662)
0.483
3
UniProt:Q8N4V1 MMGT1
1
MMGT1 [Golgi membrane]
(R-HSA-5216137)
0.483
3
UniProt:Q9NPA0 EMC7
0.483
3
UniProt:P11717 IGF2R
7
IGF2R [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869091)
IGF2R [Golgi membrane]
(R-HSA-434345)
IGF2R [cytoplasmic vesicle membrane]
(R-HSA-434213)
IGF2R [transport vesicle]
(R-HSA-6814609)
IGF2R [trans-Golgi network membrane]
(R-HSA-6814608)
IGF2R [plasma membrane]
(R-HSA-6806532)
IGF2R [secretory granule membrane]
(R-HSA-6803320)
0.483
2
UniProt:Q96S66 CLCC1
0.483
3
UniProt:Q5J8M3 EMC4
0.483
2
UniProt:P50402 EMD
4
EMD [nuclear envelope]
(R-HSA-201573)
EMD [cytosol]
(R-HSA-9613988)
EMD [endoplasmic reticulum membrane]
(R-HSA-9613998)
EMD [endosome membrane]
(R-HSA-9715092)
0.483
3
UniProt:P21860 ERBB3
0.483
3
UniProt:Q15005 SPCS2
1
SPCS2 [endoplasmic reticulum membrane]
(R-HSA-264996)
0.483
2
UniProt:Q13586 STIM1
1
STIM1 [endoplasmic reticulum membrane]
(R-HSA-434675)
0.483
3
UniProt:P61009 SPCS3
1
SPCS3 [endoplasmic reticulum membrane]
(R-HSA-264916)
0.483
2
UniProt:Q96A33 CCD47
0.483
4
UniProt:P04234 CD3D
3
CD3D [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869079)
CD3D [plasma membrane]
(R-HSA-198171)
p-Y149,Y160-CD3D [plasma membrane]
(R-HSA-202329)
0.483
2
UniProt:Q5JTV8 TOR1AIP1
1
TOR1AIP1 [cytosol]
(R-HSA-9715083)
0.483
3
UniProt:Q4KMQ2 ANO6
3
ANO6 [specific granule membrane]
(R-HSA-6799509)
ANO6 [plasma membrane]
(R-HSA-2684941)
ANO6 [tertiary granule membrane]
(R-HSA-6800903)
0.483
2
UniProt:Q8WVM8 SCFD1
1
SCFD1 [cytosol]
(R-HSA-5688147)
0.483
3
UniProt:A0A0F6B1Q8 A0A0F6B1Q8
0.462
2
UniProt:P30050 RPL12
1
RPL12 [cytosol]
(R-HSA-72408)
0.462
3
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