RFK:Mg2+ phosphorylates RIB

Stable Identifier
R-HSA-196964
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Phosphorylation of riboflavin (RIB) results in the formation of the first cofactor, flavin mononucleotide (FMN). This reaction is catalyzed by riboflavin kinase (RFK), a cytosolic enzyme existing as a monomer. It utilizes either zinc or magnesium ions in the reaction.

Literature References
PubMed ID Title Journal Year
12623014 Crystal structure of human riboflavin kinase reveals a beta barrel fold and a novel active site arch

Karthikeyan, S, Zhou, Q, Mseeh, F, Grishin, NV, Osterman, AL, Zhang, H

Structure 2003
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
riboflavin kinase activity of RFK:Mg2+ [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Created