Reactome | HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [plasma membrane]

HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [plasma membrane]

Stable Identifier

R-HSA-197577

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

2B31_HUMAN, HLA-DRB3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P79483 HLA-DRB3

Gene Names

HLA-DRB3

Chain

signal peptide:1-29, chain:30-266

Reference Genes

BioGPS Gene:3125 HLA-DRB3

CTD Gene:3125 HLA-DRB3

dbSNP Gene:3125 HLA-DRB3

ENSEMBL:ENSG00000196101 HLA-DRB3

HGNC:4951 HLA-DRB3

KEGG:hsa:3125 HLA-DRB3

Monarch:3125 HLA-DRB3

NCBI Gene:3125 HLA-DRB3

OMIM:612735 HLA-DRB3

UCSC:P79483 HLA-DRB3

Reference Transcript

RefSeq:NM_022555.3 HLA-DRB3

Other Identifiers

11723194_x_at

11759642_x_at

17027082

17029705

17039907

215193_PM_x_at

215193_x_at

2950021

2950023

2950025

2950027

2950032

2950033

2950035

2950052

2950057

2950060

3125

4048258

4048272

4048275

4048282

4048284

41723_s_at

8178802

8178811

8180003

A_23_P145336

A_24_P402222

GE532983

GO:0000139

GO:0002250

GO:0002376

GO:0002469

GO:0002503

GO:0002504

GO:0002842

GO:0005515

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0005783

GO:0005789

GO:0005886

GO:0006955

GO:0007165

GO:0010008

GO:0012507

GO:0016020

GO:0019882

GO:0019886

GO:0023026

GO:0030658

GO:0030666

GO:0030669

GO:0031410

GO:0031902

GO:0032395

GO:0032588

GO:0042605

GO:0042613

GO:0043226

GO:0050778

GO:0050852

GO:0050870

GO:0060089

GO:0065003

GO:0098553

GO:0120281

GO:2000516

HMNXSV003044723

Hs.279930.1.S1_3p_x_at

ILMN_1717261

TC6_apd_hap1000101.hg

TC6_dbb_hap3000208.hg

TC6_ssto_hap7000164.hg

Participates

as a member of

HLA II beta chain [plasma membrane] (Homo sapiens)

Other forms of this molecule

HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [lumenal side of endoplasmic reticulum membrane]

HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [ER to Golgi transport vesicle membrane]

HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [Golgi membrane]

HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [trans-Golgi network membrane]

HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [transport vesicle membrane]

HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [clathrin-coated endocytic vesicle membrane]

HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [endocytic vesicle membrane]

HLA class II histocompatibility antigen, DRB3-1 beta chain precursor [lysosomal membrane]

Inferred To

RT1-Db1 [plasma membrane] (Rattus norvegicus)

b2m [plasma membrane] (Danio rerio)

BLB2 [plasma membrane] (Gallus gallus)

H2-Eb1 [plasma membrane] (Mus musculus)

HLA class II histocompatibility antigen, DR beta 4 chain [plasma membrane] (Bos taurus)

zmp:0000001138 [plasma membrane] (Danio rerio)

mhc2-dab [plasma membrane] (Xenopus tropicalis)

LOC100153139 [plasma membrane] (Sus scrofa)

Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [plasma membrane] (Danio rerio)

Homologues of HLA class II histocompatibility antigen, DR beta 4 chain [plasma membrane] (Mus musculus)

H2-Eb2 [plasma membrane] (Mus musculus)

Cross References

RefSeq

NP_072049.2

ENSEMBL

ENST00000307137, ENSP00000302517, ENST00000383126, ENSG00000196101, ENSG00000231679, ENSP00000372607

GeneCards

HLA-DRB3

ZINC - Substances

DRB3_HUMAN

ZINC target

P79483

PRO

P79483

ZINC - Predictions - Purchasable

DRB3_HUMAN

PDB

2Q6W, 3C5J, 4H1L

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P36957 DLST	5	Lipo-K110-DLST [mitochondrial matrix] (R-HSA-69993) SuccinyllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853502) LipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853485) GlutaryllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9858581) DLST [mitochondrial matrix] (R-HSA-6792574)	0.556	3
UniProt:P27797 CALR	6	CALR [lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [phagocytic vesicle membrane] (R-HSA-1236879) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448)	0.556	3

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