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CD47 [plasma membrane]
Stable Identifier
R-HSA-197736
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Leukocyte surface antigen CD47, CD47_HUMAN, Integrin-associated protein, IAP
Icon
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Signal regulatory protein family interactions (Homo sapiens)
Phosphorylation of ITIM motif in SIRP alpha (Homo sapiens)
SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
SIRP alpha binds CD47 (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
SIRP gamma binds CD47 (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
SIRP gamma:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-4Y-SIRPA:CD47 binds GRB2-1 (Homo sapiens)
p-Y428,Y452,Y469,Y495-SIRPA:CD47:GRB2-1 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-4Y-SIRPA:CD47 binds PTK2B (Homo sapiens)
p-Y428,Y452,Y469,Y495-SIRPA:CD47:PTK2B [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-4Y-SIRPA:CD47 binds PTPN6,PTPN11 (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:PTPN6,PTPN11 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-4Y-SIRPA:CD47 binds SKAP2 (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47:SKAP2 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-4Y-SIRPA:CD47:SKAP2 binds FYB (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47:SKAP2 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496y-SIRPA:CD47:SKAP2:FYB [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47:SKAP2 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
Extracellular matrix organization (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Homo sapiens)
COMP pentamer:Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Homo sapiens)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
Hemostasis (Homo sapiens)
Cell surface interactions at the vascular wall (Homo sapiens)
CD47 binds SIRP (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
CD47-binding SIRPs:CD47 [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
Exocytosis of tertiary granule membrane proteins (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
CD47 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q08722 CD47
Gene Names
CD47, MER6
Chain
signal peptide:1-18, chain:19-323
Reference Genes
COSMIC (genes):CD47 CD47
dbSNP Gene:961 CD47
ENSEMBL:ENSG00000196776 CD47
Participates
as a component of
SIRP gamma:CD47 [plasma membrane] (Homo sapiens)
SIRPA:CD47 [plasma membrane] (Homo sapiens)
p-Y429,Y453,Y470,Y496-SIRPA:CD47 [plasma membrane] (Homo sapiens)
CD47-binding SIRPs:CD47 [plasma membrane] (Homo sapiens)
as an input of
SIRP gamma binds CD47 (Homo sapiens)
SIRP alpha binds CD47 (Homo sapiens)
CD47 binds SIRP (Homo sapiens)
as a member of
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
Integrin alpha5beta1, Integrin alphaVbeta3, CD47 [plasma membrane] (Homo sapiens)
Other forms of this molecule
CD47 [tertiary granule membrane]
CD47 [specific granule membrane]
Inferred To
CD47 [plasma membrane]
(Bos taurus)
CD47 [plasma membrane]
(Canis familiaris)
CD47 [plasma membrane]
(Gallus gallus)
CD47 [plasma membrane]
(Sus scrofa)
Cd47 [plasma membrane]
(Mus musculus)
Cd47 [plasma membrane]
(Rattus norvegicus)
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P78324 SIRPA
4
SIRPA [ficolin-1-rich granule membrane]
(R-HSA-6803321)
SIRPA [plasma membrane]
(R-HSA-3209922)
SIRPA [tertiary granule membrane]
(R-HSA-6803288)
p-Y429,Y453,Y470,Y496-SIRPA [plasma membrane]
(R-HSA-391102)
0.59
2
UniProt:Q8N205 SYNE4
0.556
3
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