ERBB4 forms heterodimers with ERBB3

Stable Identifier
R-HSA-1977958
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
ReviewStatus
5/5
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ERBB4 forms heterodimers with ERBB3
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Ligand-stimulated ERBB4 was shown to form heterodimers with ligand-stimulated ERBB3 when human ERBB4 and ERBB3 were exogenously expressed in mouse pro-B-lymphocyte cell line. Heterodimers of ERBB4 and ERBB3 undergo trans-autophosphorylation, but the exact phosphorylation pattern, downstream signaling and physiological significance of these heterodimers have not been studied (Riese et al. 1995).
Literature References
PubMed ID Title Journal Year
7565730 The cellular response to neuregulins is governed by complex interactions of the erbB receptor family

Andrews, GC, Riese DJ, 2nd, Stern, DF, Plowman, GD, van Raaij, TM

Mol Cell Biol 1995
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Authored
Orlic-Milacic, M  (2011-11-04)
Stern, DF  (2019-02-21)
Reviewed
Zeng, F  (2011-11-11)
Harris, RC  (2011-11-11)
Created
Orlic-Milacic, M  (2011-11-08)
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