Reactome | CD244 [plasma membrane]

CD244 [plasma membrane]

Stable Identifier

R-HSA-197846

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Natural killer cell receptor 2B4 precursor, C244_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q63HN8 RNF213

Expand all

External Reference Information

External Reference

UniProt:Q9BZW8 CD244

Gene Names

CD244, 2B4

Chain

signal peptide:1-21, chain:22-370

Reference Genes

BioGPS Gene:51744 CD244

COSMIC (genes):CD244 CD244

CTD Gene:51744 CD244

dbSNP Gene:51744 CD244

ENSEMBL:ENSG00000122223 CD244

HGNC:18171 CD244

KEGG:hsa:51744 CD244

Monarch:51744 CD244

NCBI Gene:51744 CD244

OMIM:605554 CD244

UCSC:Q9BZW8 CD244

Reference Transcript

Other Identifiers

11729423_at

11748899_a_at

11755979_a_at

16695447

220307_PM_at

220307_at

234320_PM_at

234320_at

2440386

2440387

2440388

2440389

2440390

2440391

2440392

2440395

2440396

2440398

2440399

2440400

2440401

2440402

2440409

2440410

2440412

51744

7921677

81541_at

A_23_P85453

A_24_P105332

A_33_P3234292

GE79836

GO:0002250

GO:0002323

GO:0002376

GO:0005515

GO:0005886

GO:0006955

GO:0007165

GO:0009897

GO:0016020

GO:0030101

GO:0032729

GO:0032757

GO:0038023

GO:0042288

GO:0045087

GO:0045121

GO:0060732

GO:0071663

GO:0098542

HMNXSV003046856

Hs.157872.1.S1_3p_at

Hs.157872.1.S1_3p_s_at

ILMN_1702534

PH_hs_0009553

PH_hs_0031906

TC01003408.hg

g7706528_3p_at

Participates

as a component of

CD48:CD244 [plasma membrane] (Homo sapiens)

as an input of

CD48 binds CD244 (Homo sapiens)

Inferred To

CD244 [plasma membrane] (Bos taurus)

CD244 [plasma membrane] (Canis familiaris)

CD244 [plasma membrane] (Gallus gallus)

CD244 [plasma membrane] (Sus scrofa)

Cd244 [plasma membrane] (Mus musculus)

Cd244 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001160136.1, NP_057466.1, XP_011507924.1, NP_001160135.1

OpenTargets

ENSG00000122223

ENSEMBL

ENST00000322302, ENST00000368034, ENST00000368033, ENSP00000313619, ENSP00000357013, ENSP00000432636, ENST00000492063, ENSP00000357012, ENSG00000122223

HPA

ENSG00000122223-CD244

GeneCards

CD244

PRO

Q9BZW8

Pharos - Targets

Q9BZW8

GlyGen

Q9BZW8

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60880 SH2D1A	1	SH2D1A [cytosol] (R-HSA-5685108)	0.866	10
UniProt:P09326 CD48	1	CD48 [plasma membrane] (R-HSA-197877)	0.786	5
UniProt:O14796 SH2D1B	1	SH2D1B [cytosol] (R-HSA-5685187)	0.688	7
UniProt:Q92835 INPP5D	2	INPP5D [cytosol] (R-HSA-197940) p-Y-INPP5D [cytosol] (R-HSA-9680730)	0.667	6
UniProt:O60880-1 SH2D1A			0.564	2
UniProt:P29350 PTPN6	5	PTPN6 [cytosol] (R-HSA-197938) PTPN6 [nucleoplasm] (R-HSA-9008911) PTPN6 [tertiary granule lumen] (R-HSA-6800952) PTPN6 [extracellular region] (R-HSA-6806315) PTPN6 [specific granule lumen] (R-HSA-6799641)	0.564	2
UniProt:Q9Y512 SAMM50	1	SAMM50 [mitochondrial outer membrane] (R-HSA-1252178)	0.527	2
UniProt:Q9BRQ6 CHCHD6	1	CHCHD6 (MIC25) [mitochondrial inner membrane] (R-HSA-8949568)	0.527	2
UniProt:Q9NP72 RAB18	6	RAB18 [endoplasmic reticulum membrane] (R-HSA-8849596) GGC-RAB18 [endoplasmic reticulum membrane] (R-HSA-8877986) GGC-RAB18 [cytosol] (R-HSA-8873762) RAB18 [cytosol] (R-HSA-8850022) RAB18 [plasma membrane] (R-HSA-6804812) RAB18 [secretory granule membrane] (R-HSA-6804804)	0.527	2
UniProt:O75431 MTX2	1	MTX2 [mitochondrial outer membrane] (R-HSA-1252142)	0.527	3
UniProt:Q96LW7 CAR19			0.527	2
UniProt:Q5SWX8 ODR4			0.527	2
UniProt:Q63HN8 RNF213	3	RNF213(1-1172)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9715284) RNF213(1-1172)-ALK(1058-1620) fusion [cytosol] (R-HSA-9715291) RNF213 [cytosol] (R-HSA-9635613)	0.527	2
UniProt:Q06124 PTPN11	4	p-Y542,Y580-PTPN11 [cytosol] (R-HSA-162573) PTPN11 [cytosol] (R-HSA-162563) PTPN11 [nucleoplasm] (R-HSA-8937745) p-Y542-PTPN11 [cytosol] (R-HSA-1369081)	0.525	5
UniProt:P19174 PLCG1	6	p-4Y-PLCG1 [plasma membrane] (R-HSA-167679) PLCG1 [cytosol] (R-HSA-202320) PLCG1 [plasma membrane] (R-HSA-167682) p-Y771,Y783,Y1254-PLCG1 [cytosol] (R-HSA-202357) p-Y771,Y783-PLCG1 [plasma membrane] (R-HSA-1169084) p-Y-PLCG1 [cytosol] (R-HSA-9029082)	0.525	2

Cite Us!