NOTCH1 stimulates MYC transcription

Stable Identifier
R-HSA-1980067
Type
Reaction [omitted]
Species
Homo sapiens
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Binding of the NOTH1 Coactivator Complex to the MYC promoter stimulates MYC transcription (Palomero et al. 2006).

Literature References
PubMed ID Title Journal Year
17114293 NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

Palomero, T, Lim, WK, Odom, DT, Sulis, ML, Real, PJ, Margolin, A, Barnes, KC, O'Neil, J, Neuberg, D, Weng, AP, Aster, JC, Sigaux, F, Soulier, J, Look, AT, Young, RA, Califano, A, Ferrando, AA

Proc Natl Acad Sci U S A 2006
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