Reactome | MDM2 [cytosol]

MDM2 [cytosol]

Stable Identifier

R-HSA-198644

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2), Ubiquitin-protein ligase E3 Mdm2 , p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2

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Locations in the PathwayBrowser for interactor UniProt:Q9UKB1 FBXW11

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External Reference Information

External Reference

UniProt:Q00987 MDM2

Gene Names

MDM2

Chain

chain:1-491

Reference Genes

BioGPS Gene:4193 MDM2

COSMIC (genes):MDM2 MDM2

CTD Gene:4193 MDM2

dbSNP Gene:4193 MDM2

ENSEMBL:ENSG00000135679 MDM2

HGNC:6973 MDM2

KEGG Gene (Homo sapiens):4193 MDM2

Monarch:4193 MDM2

NCBI Gene:4193 MDM2

OMIM:164785 MDM2

UCSC:Q00987 MDM2

Reference Transcript

Other Identifiers

0000070278

0002320113

0002690017

11731564_x_at

11731565_x_at

11731566_a_at

11731567_a_at

11731568_x_at

11753563_x_at

11753688_a_at

11753689_x_at

11753819_a_at

11753820_x_at

11756046_x_at

16753853

1859_s_at

1880_at

2008_s_at

205386_s_at

211832_s_at

217373_x_at

217542_at

217557_3p_s_at

217557_s_at

225160_x_at

229711_s_at

238733_at

244616_3p_x_at

244616_x_at

3421301

3421302

3421303

3421304

3421305

3421306

3421307

3421310

3421311

3421315

3421316

3421322

3421323

3421325

3421328

3421329

3421334

3421335

3421336

3421337

3421338

3421339

3421340

3421341

3421342

3421343

3421344

3421345

3421346

3421347

3421348

3421349

3421350

3421351

3421361

3421363

3421365

3421366

3421368

3421369

3421371

38509_at

3979479

4193

46744_s_at

53464_at

61888_at

62280_at

64992_i_at

64993_r_at

75871_at

7956989

A_14_P112137

A_14_P118388

A_14_P133404

A_14_P135914

A_23_P139895

A_23_P309545

A_23_P502750

A_24_P925664

A_33_P3361707

GE58146

GE832699

GE83502

GO:0000122

GO:0000209

GO:0000278

GO:0001568

GO:0001974

GO:0002027

GO:0002039

GO:0003013

GO:0003170

GO:0003181

GO:0003203

GO:0003281

GO:0003283

GO:0003674

GO:0003723

GO:0004842

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0005886

GO:0006464

GO:0006511

GO:0006810

GO:0006913

GO:0006950

GO:0006977

GO:0007049

GO:0007089

GO:0007165

GO:0007507

GO:0008097

GO:0008150

GO:0008219

GO:0008270

GO:0008283

GO:0008284

GO:0009056

GO:0009058

GO:0009636

GO:0010039

GO:0010468

GO:0010628

GO:0010629

GO:0010955

GO:0010977

GO:0015031

GO:0016032

GO:0016567

GO:0016579

GO:0016604

GO:0016740

GO:0016874

GO:0016925

GO:0018205

GO:0019789

GO:0019843

GO:0019899

GO:0019904

GO:0022607

GO:0030154

GO:0030666

GO:0031410

GO:0031625

GO:0031648

GO:0032026

GO:0032182

GO:0032436

GO:0032991

GO:0033612

GO:0034504

GO:0034641

GO:0036369

GO:0040011

GO:0042176

GO:0042220

GO:0042493

GO:0042802

GO:0042975

GO:0043021

GO:0043066

GO:0043130

GO:0043154

GO:0043161

GO:0043167

GO:0043226

GO:0043278

GO:0043518

GO:0044403

GO:0045184

GO:0045202

GO:0045472

GO:0045787

GO:0045892

GO:0045931

GO:0046677

GO:0046827

GO:0046872

GO:0047485

GO:0048545

GO:0048856

GO:0048870

GO:0051149

GO:0051603

GO:0051604

GO:0051865

GO:0060411

GO:0061630

GO:0061663

GO:0065003

GO:0070301

GO:0071157

GO:0071236

GO:0071301

GO:0071310

GO:0071312

GO:0071363

GO:0071375

GO:0071391

GO:0071407

GO:0071456

GO:0071480

GO:0071494

GO:0072717

GO:0097110

GO:0097718

GO:1901796

GO:1901797

GO:1902254

GO:1904404

GO:1904707

GO:1904754

GO:1990000

GO:1990785

Hs.116932.0.A1_3p_at

Hs.168732.0.A1_3p_at

Hs.168732.0.A1_3p_x_at

Hs.267158.1.S1_3p_at

Hs.272346.0.S1_3p_s_at

Hs.332938.1.S1_3p_a_at

Hs.37494.0.A1_3p_at

ILMN_1736829

ILMN_1814208

ILMN_2389851

M92424_at

PH_hs_0023082

TC12000606.hg

TC12002437.hg

U33202_s_at

U33203_s_at

g7230489_3p_s_at

Participant Of

input

output

MDM2 translocates to the cytosol

Other forms of this molecule

PolyUb-MDM2 [nucleoplasm]

SUMO1-K182-MDM2 [nucleoplasm]

MDM2 [plasma membrane]

MDM2 [endocytic vesicle membrane]

p-S166,S188,T218-MDM2 [nucleoplasm]

PolyUb,p-S166,S188-MDM2 [nucleoplasm]

p-5S,T-MDM2 [nucleoplasm]

MDM2 [nucleoplasm]

p-S166,S188-MDM2 [cytosol]

p-S166,S188-MDM2 [nucleoplasm]

Inferred To

mdm2 [cytosol] (Danio rerio)

mdm2 [cytosol] (Xenopus tropicalis)

Mdm2 [cytosol] (Mus musculus)

Mdm2 [cytosol] (Rattus norvegicus)

MDM2 [cytosol] (Canis familiaris)

MDM2 [cytosol] (Gallus gallus)

MDM2 [cytosol] (Sus scrofa)

Cross References

RefSeq

XP_005268929.1, NP_001265391.1, NP_001138811.1, XP_006719462.1, NP_002383.2

OpenTargets

ENSG00000135679

ZINC - Substances

MDM2_HUMAN

ZINC target

Q00987

PRO

Q00987

PDB

3V3B, 5VK0, 6Y4Q, 6I29, 4OCC, 3G03, 2VJF, 6Q9O, 4UE1, 5J7F, 4HG7, 2HDP, 3TJ2, 4JV9, 5OAI, 6KZU, 4ZYI, 5TRF, 3VZV, 4OBA, 5MNJ, 6Q96, 4ZGK, 4OGT, 4HBM, 4JVR, 4QOC, 1T4F, 3W69, 2MPS, 2FOP, 4JVE, 6GGN, 4ZYC, 6SQO, 5LAZ, 4JWR, 2C6B, 2GV2, 3TU1, 5LN2, 6T2E, 5AFG, 3LNZ, 3JZR, 3LBL, 5OC8, 3VBG, 5LAV, 5C5A, 5UMM, 5HMH, 3TPX, 1YCR, 4JV7, 3IUX, 4OGV, 4ERE, 6I3S, 4MDQ, 5J7G, 3IWY, 4OGN, 4ODF, 6Q9H, 5SWK, 4QO4, 5LAW, 3EQS, 1Z1M, 4DIJ, 5HMI, 6IM9, 5Z02, 4OQ3, 5ZXF, 6T2F, 2F1Y, 6H22, 4UMN, 4OAS, 5WTS, 3LNJ, 6Q9L, 2C6A, 4UD7, 6T2D, 4MDN, 6AAW, 3LBK, 2AXI, 3JZK, 2LZG, 4XXB, 4ODE, 5LAY, 5HMK, 6HFA, 3MQS, 4ZFI, 4HFZ, 4WT2, 4ERF, 1T4E, 3JZS, 5XXK, 4ZYF, 2M86, 2VJE, 2RUH, 1RV1

ZINC - Investigational

MDM2_HUMAN

HPA

ENSG00000135679-MDM2

GeneCards

Q00987

Ensembl

ENST00000299252, ENST00000258149, ENSP00000353611, ENSP00000444430, ENSP00000377065, ENST00000539479, ENSP00000299252, ENSP00000258149, ENST00000393413, ENSG00000135679, ENST00000360430

Orphanet

21735

ZINC - Predictions - Purchasable

MDM2_HUMAN

HMDB Protein

HMDBP02432

Interactors (70)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04637 TP53	27	TP53 [cytosol] (R-HSA-8869337) Unfolded TP53 [cytosol] (R-HSA-6813797) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) SUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) Me2K-370,382-TP53 [nucleoplasm] (R-HSA-3222242) p-S15,S33,S46-TP53 [nucleoplasm] (R-HSA-6805268) p-S15,S392-TP53 [nucleoplasm] (R-HSA-3222015) p-T55-TP53 [nucleoplasm] (R-HSA-6805400) p-S15,S20,S392-TP53 [nucleoplasm] (R-HSA-6805053) p-S15,S20,S269,T284-TP53 [nucleoplasm] (R-HSA-6805133) p-S315-TP53 [nucleoplasm] (R-HSA-6805106) Ac-K120,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805656) Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805631) Ac-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-5628868) Me2-K373-TP53 [nucleoplasm] (R-HSA-6805759) MeK-370,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222226) p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm] (R-HSA-6804378) Me-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222124) Me1-K372,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805719) p-S15,S20,S46-TP53 [nucleoplasm] (R-HSA-6798369) p-S37-TP53 [nucleoplasm] (R-HSA-3239022) PolyUb,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6804446) PolyUb-TP53 [nucleoplasm] (R-HSA-6793679) PolyUb-TP53 [cytosol] (R-HSA-6793681) p-S15,S20-TP53 [nucleoplasm] (R-HSA-69683) p-S15-TP53 [nucleoplasm] (R-HSA-69507) TP53 [nucleoplasm] (R-HSA-69488)	0.994	98
UniProt:Q93009 USP7	2	USP7 [nucleoplasm] (R-HSA-3215278) USP7 [cytosol] (R-HSA-8853511)	0.959	27
UniProt:O15151 MDM4	5	PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm] (R-HSA-6804938) PolyUb-MDM4 [nucleoplasm] (R-HSA-6782502) p-S346,S367,S403-MDM4 [nucleoplasm] (R-HSA-349441) p-S403-MDM4 [nucleoplasm] (R-HSA-349461) MDM4 [nucleoplasm] (R-HSA-349430)	0.932	13
UniProt:P62913 RPL11	1	RPL11 [cytosol] (R-HSA-72406)	0.912	11
UniProt:Q9UER7 DAXX	13	DAXX L98Vfs13 [nucleoplasm] (R-HSA-9673102) SUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086) DAXX R48Vfs93 [nucleoplasm] (R-HSA-9673103) DAXX C74* [nucleoplasm] (R-HSA-9673096) DAXX S138* [nucleoplasm] (R-HSA-9673081) DAXX H26Tfs118 [nucleoplasm] (R-HSA-9673114) DAXX E104 [nucleoplasm] (R-HSA-9673078) DAXX E72Nfs72 [nucleoplasm] (R-HSA-9673110) DAXX C106 [nucleoplasm] (R-HSA-9673079) DAXX A103Sfs40 [nucleoplasm] (R-HSA-9673121) DAXX K56 [nucleoplasm] (R-HSA-9673089) DAXX A36Qfs*108 [nucleoplasm] (R-HSA-9673105) DAXX [nucleoplasm] (R-HSA-3222068)	0.895	18
UniProt:P31749 AKT1	13	p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308-AKT1 [cytosol] (R-HSA-198634) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) AKT1 [cytosol] (R-HSA-58252) AKT1 [plasma membrane] (R-HSA-199416) p-S473-AKT1 [plasma membrane] (R-HSA-377265) p-T308,S473-AKT1 [cytosol] (R-HSA-198356)	0.828	6
UniProt:P0CG48 UBC	325	UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-566-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-338-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-186-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-262-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-414-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-110-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-642-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-488-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-291-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783193) Ub-595-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783130) Ub-443-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783153) Ub-139-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783155) Ub-63-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783094) Ub-671-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783083) Ub-519-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783053) Ub-367-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783105) Ub-215-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783137) Ub-386-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783067) Ub-6-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783122) Ub-310-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783027) Ub-234-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783157) Ub-614-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783063) Ub-462-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783118) Ub-538-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783011) Ub-158-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783140) Ub-82-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783175) Ub-315-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783089) Ub-163-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783091) Ub-543-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783060) Ub-239-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783092) Ub-619-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783125) Ub-467-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783181) Ub-11-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783104) Ub-391-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783170) Ub-87-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783110) Ub-656-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783134) Ub-124-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783120) Ub-428-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783090) Ub-48-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783029) Ub-504-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783113) Ub-200-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783150) Ub-580-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783119) Ub-276-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783183) Ub-352-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783201) Ub-29-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783064) Ub-182-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783097) Ub-486-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783194) Ub-334-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783199) Ub-638-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783188) Ub-106-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783031) Ub-258-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783016) Ub-562-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783172) Ub-410-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783077) Ub-636-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783128) Ub-104-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783032) Ub-256-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783004) Ub-484-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783156) Ub-27-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783022) Ub-332-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783138) Ub-180-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783107) Ub-408-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783108) Ub-560-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783174) N6-glycyl-L-lysine-UBC(457-532) [cytosol] (R-HSA-8869048) N6-glycyl-L-lysine-UBC(609-684) [cytosol] (R-HSA-8869052) N6-glycyl-L-lysine-UBC(229-304) [cytosol] (R-HSA-8869032) N6-glycyl-L-lysine-UBC(533-608) [cytosol] (R-HSA-8869033) N6-glycyl-L-lysine-UBC(153-228) [cytosol] (R-HSA-8869035) N6-glycyl-L-lysine-UBC(305-380) [cytosol] (R-HSA-8869036) N6-glycyl-L-lysine-UBC(77-152) [cytosol] (R-HSA-8869026) N6-glycyl-L-lysine-UBC(1-76) [cytosol] (R-HSA-8869030) N6-glycyl-L-lysine-UBC(381-456) [cytosol] (R-HSA-8869031) adenylatedG608-UBC(533-608) [nucleoplasm] (R-HSA-8852090) adenylatedG380-UBC(305-380) [nucleoplasm] (R-HSA-8852093) adenylatedG532-UBC(457-532) [nucleoplasm] (R-HSA-8852081) adenylatedG304-UBC(229-304) [nucleoplasm] (R-HSA-8852050) adenylatedG152-UBC(77-152) [nucleoplasm] (R-HSA-8852054) adenylatedG684-UBC(609-684) [nucleoplasm] (R-HSA-8852105) adenylatedG228-UBC(153-228) [nucleoplasm] (R-HSA-8852075) adenylatedG76-UBC(1-76) [nucleoplasm] (R-HSA-8852044) adenylatedG456-UBC(381-456) [nucleoplasm] (R-HSA-8852098) UBC [cytosol] (R-HSA-8853531) adenylatedG380-UBC(305-380) [cytosol] (R-HSA-8852062) adenylatedG608-UBC(533-608) [cytosol] (R-HSA-8852052) adenylatedG76-UBC(1-76) [cytosol] (R-HSA-8852053) adenylatedG304-UBC(229-304) [cytosol] (R-HSA-8852117) adenylatedG684-UBC(609-684) [cytosol] (R-HSA-8852118) adenylatedG152-UBC(77-152) [cytosol] (R-HSA-8852087) adenylatedG532-UBC(457-532) [cytosol] (R-HSA-8852045) adenylatedG228-UBC(153-228) [cytosol] (R-HSA-8852111) adenylatedG456-UBC(381-456) [cytosol] (R-HSA-8852069) Ub-428-UBC(381-456) [endoplasmic reticulum membrane] (R-HSA-8943062) Ub-656-UBC(609-684) [endoplasmic reticulum membrane] (R-HSA-8943120) Ub-124-UBC(77-152) [endoplasmic reticulum membrane] (R-HSA-8943129) Ub-48-UBC(1-76) [endoplasmic reticulum membrane] (R-HSA-8943079) Ub-352-UBC(305-380) [endoplasmic reticulum membrane] (R-HSA-8943108) Ub-504-UBC(457-532) [endoplasmic reticulum membrane] (R-HSA-8943075) Ub-276-UBC(229-304) [endoplasmic reticulum membrane] (R-HSA-8943106) Ub-580-UBC(533-608) [endoplasmic reticulum membrane] (R-HSA-8943137) Ub-200-UBC(153-228) [endoplasmic reticulum membrane] (R-HSA-8943087) UBC(1-76) [plasma membrane] (R-HSA-3149469) UBC(457-532) [plasma membrane] (R-HSA-3149468) UBC(153-228) [plasma membrane] (R-HSA-3149467) UBC(609-684) [plasma membrane] (R-HSA-3149466) UBC(77-152) [plasma membrane] (R-HSA-3149465) UBC(229-304) [plasma membrane] (R-HSA-3149464) UBC(533-608) [plasma membrane] (R-HSA-3149462) UBC(381-456) [plasma membrane] (R-HSA-3149459) UBC(305-380) [plasma membrane] (R-HSA-3149458) UBC(1-76) [endosome membrane] (R-HSA-939187) UBC(533-608) [endosome membrane] (R-HSA-939221) UBC(77-152) [endosome membrane] (R-HSA-939161) UBC(305-380) [endosome membrane] (R-HSA-939196) UBC(457-532) [endosome membrane] (R-HSA-939199) UBC(381-456) [endosome membrane] (R-HSA-939166) UBC(153-228) [endosome membrane] (R-HSA-939170) UBC(609-684) [endosome membrane] (R-HSA-939237) UBC(229-304) [endosome membrane] (R-HSA-939172) UBC(77-152) [endoplasmic reticulum membrane] (R-HSA-8943095) UBC(381-456) [endoplasmic reticulum membrane] (R-HSA-8943126) UBC(533-608) [endoplasmic reticulum membrane] (R-HSA-8943061) UBC(609-684) [endoplasmic reticulum membrane] (R-HSA-8943135) UBC(229-304) [endoplasmic reticulum membrane] (R-HSA-8943103) UBC(153-228) [endoplasmic reticulum membrane] (R-HSA-8943068) UBC(1-76) [endoplasmic reticulum membrane] (R-HSA-8943077) UBC(305-380) [endoplasmic reticulum membrane] (R-HSA-8943084) UBC(457-532) [endoplasmic reticulum membrane] (R-HSA-8943112) Ub-29-UBC(1-76) [cytosol] (R-HSA-5689165) Ub-258-UBC(229-304) [cytosol] (R-HSA-5689167) Ub-334-UBC(305-380) [cytosol] (R-HSA-5689166) Ub-410-UBC(381-456) [cytosol] (R-HSA-5689185) Ub-486-UBC(457-532) [cytosol] (R-HSA-5689176) Ub-562-UBC(533-608) [cytosol] (R-HSA-5689151) Ub-106-UBC(77-152) [cytosol] (R-HSA-5689183) Ub-182-UBC(153-228) [cytosol] (R-HSA-5689169) Ub-638-UBC(609-684) [cytosol] (R-HSA-5689136) Ub-310-UBC(305-380) [cytosol] (R-HSA-5689097) Ub-6-UBC(1-76) [cytosol] (R-HSA-5689091) Ub-462-UBC(457-532) [cytosol] (R-HSA-5689092) Ub-386-UBC(381-456) [cytosol] (R-HSA-5689086) Ub-538-UBC(533-608) [cytosol] (R-HSA-5689104) Ub-158-UBC(153-228) [cytosol] (R-HSA-5689107) Ub-614-UBC(609-684) [cytosol] (R-HSA-5689076) Ub-234-UBC(229-304) [cytosol] (R-HSA-5689110) Ub-82-UBC(77-152) [cytosol] (R-HSA-5689078) Ub-110-UBC(77-152) [cytosol] (R-HSA-5689196) Ub-33-UBC(1-76) [cytosol] (R-HSA-5689134) Ub-488-UBC(457-532) [cytosol] (R-HSA-5689153) Ub-338-UBC(305-380) [cytosol] (R-HSA-5689152) Ub-642-UBC(609-684) [cytosol] (R-HSA-5689218) Ub-414-UBC(381-456) [cytosol] (R-HSA-5689157) Ub-262-UBC(229-304) [cytosol] (R-HSA-5689150) Ub-566-UBC(533-608) [cytosol] (R-HSA-5689205) Ub-186-UBC(153-228) [cytosol] (R-HSA-5689140) Ub-256-UBC(229-304) [cytosol] (R-HSA-5689135) Ub-180-UBC(153-228) [cytosol] (R-HSA-5689221) Ub-104-UBC(77-152) [cytosol] (R-HSA-5689189) Ub-484-UBC(457-532) [cytosol] (R-HSA-5689220) Ub-560-UBC(533-608) [cytosol] (R-HSA-5689145) Ub-636-UBC(609-684) [cytosol] (R-HSA-5689144) Ub-332-UBC(305-380) [cytosol] (R-HSA-5689211) Ub-27-UBC(1-76) [cytosol] (R-HSA-5689179) Ub-408-UBC(381-456) [cytosol] (R-HSA-5689182) Ub-87-UBC(77-152) [cytosol] (R-HSA-3095920) Ub-163-UBC(153-228) [cytosol] (R-HSA-3095924) Ub-619-UBC(609-684) [cytosol] (R-HSA-3095925) Ub-467-UBC(457-532) [cytosol] (R-HSA-3095935) Ub-11-UBC(1-76) [cytosol] (R-HSA-3095906) Ub-543-UBC(533-608) [cytosol] (R-HSA-3095912) Ub-391-UBC(381-456) [cytosol] (R-HSA-3095914) Ub-315-UBC(305-380) [cytosol] (R-HSA-3095916) Ub-239-UBC(229-304) [cytosol] (R-HSA-3095919) Ub-519-UBC(457-532) [endosome membrane] (R-HSA-939227) Ub-367-UBC(305-380) [endosome membrane] (R-HSA-939162) Ub-291-UBC(229-304) [endosome membrane] (R-HSA-939226) Ub-443-UBC(381-456) [endosome membrane] (R-HSA-939204) Ub-215-UBC(153-228) [endosome membrane] (R-HSA-939175) Ub-63-UBC(1-76) [endosome membrane] (R-HSA-939174) Ub-595-UBC(533-608) [endosome membrane] (R-HSA-939242) Ub-139-UBC(77-152) [endosome membrane] (R-HSA-939244) Ub-671-UBC(609-684) [endosome membrane] (R-HSA-939183) Ub-291-UBC(229-304) [plasma membrane] (R-HSA-939859) Ub-595-UBC(533-608) [plasma membrane] (R-HSA-939858) Ub-367-UBC(305-380) [plasma membrane] (R-HSA-939861) Ub-63-UBC(1-76) [plasma membrane] (R-HSA-939860) Ub-139-UBC(77-152) [plasma membrane] (R-HSA-939865) Ub-215-UBC(153-228) [plasma membrane] (R-HSA-939864) Ub-519-UBC(457-532) [plasma membrane] (R-HSA-939845) Ub-671-UBC(609-684) [plasma membrane] (R-HSA-939846) Ub-443-UBC(381-456) [plasma membrane] (R-HSA-939848) Ub-408-UBC(381-456) [nucleoplasm] (R-HSA-6782681) Ub-484-UBC(457-532) [nucleoplasm] (R-HSA-6782650) Ub-104-UBC(77-152) [nucleoplasm] (R-HSA-6782651) Ub-256-UBC(229-304) [nucleoplasm] (R-HSA-6782641) Ub-180-UBC(153-228) [nucleoplasm] (R-HSA-6782603) Ub-560-UBC(533-608) [nucleoplasm] (R-HSA-6782637) Ub-27-UBC(1-76) [nucleoplasm] (R-HSA-6782625) Ub-636-UBC(609-684) [nucleoplasm] (R-HSA-6782597) Ub-332-UBC(305-380) [nucleoplasm] (R-HSA-6782630) Ub-638-UBC(609-684) [nucleoplasm] (R-HSA-6782680) Ub-258-UBC(229-304) [nucleoplasm] (R-HSA-6782621) Ub-562-UBC(533-608) [nucleoplasm] (R-HSA-6782672) Ub-410-UBC(381-456) [nucleoplasm] (R-HSA-6782642) Ub-182-UBC(153-228) [nucleoplasm] (R-HSA-6782678) Ub-106-UBC(77-152) [nucleoplasm] (R-HSA-6782602) Ub-334-UBC(305-380) [nucleoplasm] (R-HSA-6782638) Ub-29-UBC(1-76) [nucleoplasm] (R-HSA-6782659) Ub-486-UBC(457-532) [nucleoplasm] (R-HSA-6782661) Ub-48-UBC(1-76) [nucleoplasm] (R-HSA-6782524) Ub-428-UBC(381-456) [nucleoplasm] (R-HSA-6782462) Ub-504-UBC(457-532) [nucleoplasm] (R-HSA-6782512) Ub-276-UBC(229-304) [nucleoplasm] (R-HSA-6782482) Ub-200-UBC(153-228) [nucleoplasm] (R-HSA-6782487) Ub-656-UBC(609-684) [nucleoplasm] (R-HSA-6782474) Ub-580-UBC(533-608) [nucleoplasm] (R-HSA-6782477) Ub-124-UBC(77-152) [nucleoplasm] (R-HSA-6782498) Ub-352-UBC(305-380) [nucleoplasm] (R-HSA-6782467) Ub-467-UBC(457-532) [nucleoplasm] (R-HSA-6782619) Ub-163-UBC(153-228) [nucleoplasm] (R-HSA-6782622) Ub-11-UBC(1-76) [nucleoplasm] (R-HSA-6782609) Ub-87-UBC(77-152) [nucleoplasm] (R-HSA-6782632) Ub-239-UBC(229-304) [nucleoplasm] (R-HSA-6782669) Ub-543-UBC(533-608) [nucleoplasm] (R-HSA-6782594) Ub-391-UBC(381-456) [nucleoplasm] (R-HSA-6782626) Ub-315-UBC(305-380) [nucleoplasm] (R-HSA-6782660) Ub-619-UBC(609-684) [nucleoplasm] (R-HSA-6782662) Ub-186-UBC(153-228) [nucleoplasm] (R-HSA-6782617) Ub-338-UBC(305-380) [nucleoplasm] (R-HSA-6782620) Ub-33-UBC(1-76) [nucleoplasm] (R-HSA-6782653) Ub-110-UBC(77-152) [nucleoplasm] (R-HSA-6782590) Ub-262-UBC(229-304) [nucleoplasm] (R-HSA-6782640) Ub-642-UBC(609-684) [nucleoplasm] (R-HSA-6782674) Ub-566-UBC(533-608) [nucleoplasm] (R-HSA-6782646) Ub-414-UBC(381-456) [nucleoplasm] (R-HSA-6782636) Ub-488-UBC(457-532) [nucleoplasm] (R-HSA-6782599) UBC(229-304) [nucleoplasm] (R-HSA-939857) UBC(381-456) [nucleoplasm] (R-HSA-939856) UBC(305-380) [nucleoplasm] (R-HSA-939863) UBC(457-532) [nucleoplasm] (R-HSA-939862) UBC(533-608) [nucleoplasm] (R-HSA-939866) UBC(77-152) [nucleoplasm] (R-HSA-939869) UBC(609-684) [nucleoplasm] (R-HSA-939868) UBC(1-76) [nucleoplasm] (R-HSA-939871) UBC(153-228) [nucleoplasm] (R-HSA-939853) Ub-124-UBC(77-152) [nucleoplasm] (R-HSA-5683048) Ub-580-UBC(533-608) [nucleoplasm] (R-HSA-5683050) Ub-428-UBC(381-456) [nucleoplasm] (R-HSA-5683041) Ub-276-UBC(229-304) [nucleoplasm] (R-HSA-5683042) Ub-352-UBC(305-380) [nucleoplasm] (R-HSA-5683045) Ub-200-UBC(153-228) [nucleoplasm] (R-HSA-5683046) Ub-48-UBC(1-76) [nucleoplasm] (R-HSA-5683033) Ub-656-UBC(609-684) [nucleoplasm] (R-HSA-5683035) Ub-504-UBC(457-532) [nucleoplasm] (R-HSA-5683039) Ub-671-UBC(609-684) [nucleoplasm] (R-HSA-6782523) Ub-215-UBC(153-228) [nucleoplasm] (R-HSA-6782491) Ub-63-UBC(1-76) [nucleoplasm] (R-HSA-6782492) Ub-443-UBC(381-456) [nucleoplasm] (R-HSA-6782480) Ub-367-UBC(305-380) [nucleoplasm] (R-HSA-6782479) Ub-139-UBC(77-152) [nucleoplasm] (R-HSA-6782496) Ub-519-UBC(457-532) [nucleoplasm] (R-HSA-6782497) Ub-595-UBC(533-608) [nucleoplasm] (R-HSA-6782499) Ub-291-UBC(229-304) [nucleoplasm] (R-HSA-6782500) Ub-82-UBC(77-152) [nucleoplasm] (R-HSA-6782675) Ub-6-UBC(1-76) [nucleoplasm] (R-HSA-6782611) Ub-234-UBC(229-304) [nucleoplasm] (R-HSA-6782677) Ub-158-UBC(153-228) [nucleoplasm] (R-HSA-6782645) Ub-310-UBC(305-380) [nucleoplasm] (R-HSA-6782614) Ub-538-UBC(533-608) [nucleoplasm] (R-HSA-6782664) Ub-462-UBC(457-532) [nucleoplasm] (R-HSA-6782634) Ub-386-UBC(381-456) [nucleoplasm] (R-HSA-6782605) Ub-614-UBC(609-684) [nucleoplasm] (R-HSA-6782657) UBC(609-684) [late endosome lumen] (R-HSA-9660012) UBC(153-228) [late endosome lumen] (R-HSA-9659979) UBC(305-380) [late endosome lumen] (R-HSA-9660033) UBC(77-152) [late endosome lumen] (R-HSA-9659992) UBC(533-608) [late endosome lumen] (R-HSA-9659993) UBC(229-304) [late endosome lumen] (R-HSA-9659994) UBC(457-532) [late endosome lumen] (R-HSA-9659995) UBC(381-456) [late endosome lumen] (R-HSA-9660023) UBC(1-76) [late endosome lumen] (R-HSA-9659985) Ub-48-UBC(1-76) [cytosol] (R-HSA-939219) Ub-656-UBC(609-684) [cytosol] (R-HSA-939255) Ub-428-UBC(381-456) [cytosol] (R-HSA-939190) Ub-504-UBC(457-532) [cytosol] (R-HSA-939257) Ub-580-UBC(533-608) [cytosol] (R-HSA-939256) Ub-276-UBC(229-304) [cytosol] (R-HSA-939207) Ub-124-UBC(77-152) [cytosol] (R-HSA-939209) Ub-200-UBC(153-228) [cytosol] (R-HSA-939179) Ub-352-UBC(305-380) [cytosol] (R-HSA-939181) UBC(457-532) [cytosol] (R-HSA-939184) UBC(1-76) [cytosol] (R-HSA-939188) UBC(381-456) [cytosol] (R-HSA-939191) UBC(229-304) [cytosol] (R-HSA-939192) UBC(153-228) [cytosol] (R-HSA-939258) UBC(609-684) [cytosol] (R-HSA-939165) UBC(77-152) [cytosol] (R-HSA-939164) UBC(305-380) [cytosol] (R-HSA-939232) UBC(533-608) [cytosol] (R-HSA-939239) UBC(1-76) [lysosomal lumen] (R-HSA-9659981) UBC(305-380) [lysosomal lumen] (R-HSA-9660008) UBC(77-152) [lysosomal lumen] (R-HSA-9659978) UBC(609-684) [lysosomal lumen] (R-HSA-9660020) UBC(153-228) [lysosomal lumen] (R-HSA-9659988) UBC(457-532) [lysosomal lumen] (R-HSA-9659989) UBC(381-456) [lysosomal lumen] (R-HSA-9659984) UBC(229-304) [lysosomal lumen] (R-HSA-9660018) UBC(533-608) [lysosomal lumen] (R-HSA-9659987) Ub-215-UBC(153-228) [cytosol] (R-HSA-939186) Ub-139-UBC(77-152) [cytosol] (R-HSA-939254) Ub-595-UBC(533-608) [cytosol] (R-HSA-939198) Ub-291-UBC(229-304) [cytosol] (R-HSA-939173) Ub-367-UBC(305-380) [cytosol] (R-HSA-939206) Ub-671-UBC(609-684) [cytosol] (R-HSA-939241) Ub-63-UBC(1-76) [cytosol] (R-HSA-939176) Ub-519-UBC(457-532) [cytosol] (R-HSA-939212) Ub-443-UBC(381-456) [cytosol] (R-HSA-939182)	0.821	6
UniProt:Q8N726 CDKN2A	12	p14ARF [cytosol] (R-HSA-9645669) p14ARF [nucleoplasm] (R-HSA-1629813) p14ARF [mitochondrial matrix] (R-HSA-9645695) p14ARF R98L;R99S [cytosol] (R-HSA-9645730) p14ARF R82C [cytosol] (R-HSA-9645750) p14ARF R90H [cytosol] (R-HSA-9645755) p14ARF R88Q [cytosol] (R-HSA-9645754) p14ARF R87C [cytosol] (R-HSA-9645759) p14ARF R81G [cytosol] (R-HSA-9645741) p14ARF R98Q [cytosol] (R-HSA-9645757) p14ARF R99C [cytosol] (R-HSA-9645756) p14ARF R21RfsTER47 [cytosol] (R-HSA-9646285)	0.813	5
UniProt:P62081 RPS7	2	RPS7 [cytosol] (R-HSA-72383) RPS7 [nucleoplasm] (R-HSA-6790635)	0.75	15
UniProt:Q00987 MDM2	11	SUMO1-K182-MDM2 [nucleoplasm] (R-HSA-3000408) PolyUb-MDM2 [nucleoplasm] (R-HSA-6782472) MDM2 [plasma membrane] (R-HSA-416843) MDM2 [endocytic vesicle membrane] (R-HSA-416849) p-S166,S188,T218-MDM2 [nucleoplasm] (R-HSA-6792862) PolyUb,p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6795669) p-5S,T-MDM2 [nucleoplasm] (R-HSA-6804954) MDM2 [nucleoplasm] (R-HSA-69486) MDM2 [cytosol] (R-HSA-198644) p-S166,S188-MDM2 [cytosol] (R-HSA-198638) p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6793669)	0.736	4
UniProt:P06400 RB1	394	RB1 C706F [nucleoplasm] (R-HSA-9659812) RB1 R661W [nucleoplasm] (R-HSA-9659801) RB1 N480del [nucleoplasm] (R-HSA-9659792) RB1 C706Y [nucleoplasm] (R-HSA-9659821) RB1 R661Q [nucleoplasm] (R-HSA-9659807) RB1 I703_E737del [nucleoplasm] (R-HSA-9661065) RB1 R830_G887del [cytosol] (R-HSA-9661059) RB1 K791* [cytosol] (R-HSA-9662284) RB1 Q176* [cytosol] (R-HSA-9661774) RB1 S114* [cytosol] (R-HSA-9661775) RB1 K765* [cytosol] (R-HSA-9662281) RB1 W99* [cytosol] (R-HSA-9661769) RB1 S149* [cytosol] (R-HSA-9661770) RB1 E166* [cytosol] (R-HSA-9661767) RB1 G100* [cytosol] (R-HSA-9661763) RB1 E125* [cytosol] (R-HSA-9661784) RB1 Q121* [cytosol] (R-HSA-9661780) RB1 E184* [cytosol] (R-HSA-9661781) RB1 E137* [cytosol] (R-HSA-9661782) RB1 K745* [cytosol] (R-HSA-9662288) RB1 E209* [cytosol] (R-HSA-9661776) RB1 S618* [cytosol] (R-HSA-9662240) RB1 S463* [cytosol] (R-HSA-9662241) RB1 K720* [cytosol] (R-HSA-9662269) RB1 K429* [cytosol] (R-HSA-9662270) RB1 K652* [cytosol] (R-HSA-9662271) RB1 K715* [cytosol] (R-HSA-9662264) RB1 K615* [cytosol] (R-HSA-9662266) RB1 K412* [cytosol] (R-HSA-9662261) RB1 S567* [cytosol] (R-HSA-9662218) RB1 S807* [cytosol] (R-HSA-9662212) RB1 R467* [cytosol] (R-HSA-9662213) RB1 S834* [cytosol] (R-HSA-9662210) RB1 S576* [cytosol] (R-HSA-9662237) RB1 S758* [cytosol] (R-HSA-9662232) RB1 R7Pfs24 [cytosol] (R-HSA-9686292) RB1 S443 [cytosol] (R-HSA-9662230) RB1 S648* [cytosol] (R-HSA-9662224) RB1 S391* [cytosol] (R-HSA-9662225) RB1 S829* [cytosol] (R-HSA-9662226) RB1 D32Tfs33 [cytosol] (R-HSA-9688044) RB1 Y651Ifs7 [cytosol] (R-HSA-9688045) RB1 K143Mfs19 [cytosol] (R-HSA-9688046) RB1 V754Sfs4 [cytosol] (R-HSA-9688047) RB1 L44Rfs4 [cytosol] (R-HSA-9688040) RB1 E97Gfs13 [cytosol] (R-HSA-9688041) RB1 I679* [cytosol] (R-HSA-9688042) RB1 W195* [cytosol] (R-HSA-9689579) RB1 G100Efs11 [cytosol] (R-HSA-9688043) RB1 S648Tfs4 [cytosol] (R-HSA-9688036) RB1 H281Qfs6 [cytosol] (R-HSA-9688037) RB1 Q384 [cytosol] (R-HSA-9661925) RB1 S182Yfs2 [cytosol] (R-HSA-9688038) RB1 L343Sfs3 [cytosol] (R-HSA-9688039) RB1 L337Wfs12 [cytosol] (R-HSA-9688032) RB1 S318 [cytosol] (R-HSA-9688033) RB1 N627Mfs16 [cytosol] (R-HSA-9688034) RB1 N290Kfs20 [cytosol] (R-HSA-9688035) RB1 F299Lfs4 [cytosol] (R-HSA-9688060) RB1 Q637 [cytosol] (R-HSA-9662460) RB1 L76* [cytosol] (R-HSA-9688061) RB1 Q762* [cytosol] (R-HSA-9662461) RB1 Y655Lfs4 [cytosol] (R-HSA-9688062) RB1 N480Kfs13 [cytosol] (R-HSA-9688063) RB1 Q444* [cytosol] (R-HSA-9662463) RB1 T77Lfs34 [cytosol] (R-HSA-9688056) RB1 E747Gfs3 [cytosol] (R-HSA-9688057) RB1 M825* [cytosol] (R-HSA-9688058) RB1 L649Ffs11 [cytosol] (R-HSA-9688059) RB1 N472Ifs6 [cytosol] (R-HSA-9688052) RB1 Y813Kfs12 [cytosol] (R-HSA-9688053) RB1 I324Mfs17 [cytosol] (R-HSA-9688054) RB1 M460Ifs3 [cytosol] (R-HSA-9688055) RB1 Y655Ifs3 [cytosol] (R-HSA-9688048) RB1 L769Cfs41 [cytosol] (R-HSA-9688049) RB1 P28Lfs37 [cytosol] (R-HSA-9688050) RB1 E677Dfs19 [cytosol] (R-HSA-9688051) RB1 P370Lfs10 [cytosol] (R-HSA-9688012) RB1 N593Tfs11 [cytosol] (R-HSA-9688013) RB1 K329 [cytosol] (R-HSA-9661901) RB1 S249Ffs22 [cytosol] (R-HSA-9688014) RB1 K240 [cytosol] (R-HSA-9661902) RB1 L199Ffs4 [cytosol] (R-HSA-9688015) RB1 P253Gfs5 [cytosol] (R-HSA-9688008) RB1 K289* [cytosol] (R-HSA-9661896) RB1 S360Pfs2 [cytosol] (R-HSA-9688009) RB1 E323Kfs9 [cytosol] (R-HSA-9688010) RB1 L326* [cytosol] (R-HSA-9688011) RB1 P808Kfs12 [cytosol] (R-HSA-9688004) RB1 D584Nfs2 [cytosol] (R-HSA-9688005) RB1 N406Kfs4 [cytosol] (R-HSA-9688006) RB1 K417Wfs23 [cytosol] (R-HSA-9688007) RB1 L797Ffs18 [cytosol] (R-HSA-9688000) RB1 Q266Hfs2 [cytosol] (R-HSA-9688001) RB1 R255* [cytosol] (R-HSA-9661889) RB1 K4* [cytosol] (R-HSA-9661377) RB1 P641Afs12 [cytosol] (R-HSA-9688002) RB1 V450Sfs13 [cytosol] (R-HSA-9688003) RB1 K524Rfs28 [cytosol] (R-HSA-9688028) RB1 E280 [cytosol] (R-HSA-9661916) RB1 M825Ifs13 [cytosol] (R-HSA-9688029) RB1 M761Nfs21 [cytosol] (R-HSA-9688030) RB1 A11Rfs20 [cytosol] (R-HSA-9688031) RB1 E275 [cytosol] (R-HSA-9661919) RB1 A635Gfs6 [cytosol] (R-HSA-9688024) RB1 Q266 [cytosol] (R-HSA-9661912) RB1 I66Yfs11 [cytosol] (R-HSA-9688025) RB1 Q257 [cytosol] (R-HSA-9661913) RB1 P39Rfs26 [cytosol] (R-HSA-9688026) RB1 T664Nfs4 [cytosol] (R-HSA-9688027) RB1 Y771Lfs24 [cytosol] (R-HSA-9688020) RB1 R320Dfs12 [cytosol] (R-HSA-9688021) RB1 E282* [cytosol] (R-HSA-9661909) RB1 L277Pfs9 [cytosol] (R-HSA-9688022) RB1 I124 [cytosol] (R-HSA-9688023) RB1 N803Tfs7 [cytosol] (R-HSA-9688016) RB1 M386Ifs11 [cytosol] (R-HSA-9688017) RB1 E72Vfs34 [cytosol] (R-HSA-9688018) RB1 R150Kfs7 [cytosol] (R-HSA-9688019) RB1 L743* [cytosol] (R-HSA-9687980) RB1 R7Efs58 [cytosol] (R-HSA-9687981) RB1 T140Nfs6 [cytosol] (R-HSA-9687982) RB1 D479Efs16 [cytosol] (R-HSA-9687983) RB1 L199 [cytosol] (R-HSA-9661871) RB1 G801* [cytosol] (R-HSA-9662377) RB1 S215* [cytosol] (R-HSA-9661866) RB1 G435* [cytosol] (R-HSA-9662368) RB1 G581* [cytosol] (R-HSA-9662369) RB1 L134* [cytosol] (R-HSA-9687996) RB1 Y529Lfs26 [cytosol] (R-HSA-9687997) RB1 S816Qfs10 [cytosol] (R-HSA-9687998) RB1 E693Nfs3 [cytosol] (R-HSA-9687999) RB1 D346Rfs4 [cytosol] (R-HSA-9687992) RB1 Q35* [cytosol] (R-HSA-9661368) RB1 I806Lfs10 [cytosol] (R-HSA-9687993) RB1 E54 [cytosol] (R-HSA-9661369) RB1 L199Yfs2 [cytosol] (R-HSA-9687994) RB1 E48 [cytosol] (R-HSA-9661370) RB1 N854* [cytosol] (R-HSA-9687995) RB1 W75* [cytosol] (R-HSA-9661371) RB1 L389Ffs3 [cytosol] (R-HSA-9687988) RB1 S230 [cytosol] (R-HSA-9661876) RB1 H483Sfs10 [cytosol] (R-HSA-9687989) RB1 S842 [cytosol] (R-HSA-9687990) RB1 W78* [cytosol] (R-HSA-9661366) RB1 G449Efs8 [cytosol] (R-HSA-9687991) RB1 K63 [cytosol] (R-HSA-9661367) RB1 K537Nfs14 [cytosol] (R-HSA-9687984) RB1 L206 [cytosol] (R-HSA-9661872) RB1 K63Rfs38 [cytosol] (R-HSA-9687985) RB1 P732Lfs12 [cytosol] (R-HSA-9687986) RB1 L158* [cytosol] (R-HSA-9661874) RB1 A562Hfs49 [cytosol] (R-HSA-9687987) RB1 E72 [cytosol] (R-HSA-9661363) RB1 G540Afs3 [cytosol] (R-HSA-9688172) RB1 N328Ifs4 [cytosol] (R-HSA-9688173) RB1 E843* [cytosol] (R-HSA-9662573) RB1 L385* [cytosol] (R-HSA-9688174) RB1 E464* [cytosol] (R-HSA-9662574) RB1 N123Tfs2 [cytosol] (R-HSA-9688175) RB1 E112Dfs6 [cytosol] (R-HSA-9688168) RB1 E748* [cytosol] (R-HSA-9662568) RB1 M148Ifs8 [cytosol] (R-HSA-9688169) RB1 R661 [cytosol] (R-HSA-9688170) RB1 Y453* [cytosol] (R-HSA-9688164) RB1 K95* [cytosol] (R-HSA-9661540) RB1 M484Vfs8 [cytosol] (R-HSA-9688165) RB1 E533 [cytosol] (R-HSA-9662565) RB1 G86* [cytosol] (R-HSA-9661541) RB1 V654Sfs14 [cytosol] (R-HSA-9688166) RB1 E747 [cytosol] (R-HSA-9662566) RB1 E79* [cytosol] (R-HSA-9661542) RB1 C553Wfs53 [cytosol] (R-HSA-9688167) RB1 E677 [cytosol] (R-HSA-9662567) RB1 K96* [cytosol] (R-HSA-9661543) RB1 C102Yfs7 [cytosol] (R-HSA-9688160) RB1 E737 [cytosol] (R-HSA-9662560) RB1 E97* [cytosol] (R-HSA-9661536) RB1 R579Qfs29 [cytosol] (R-HSA-9688161) RB1 A525Pfs7 [cytosol] (R-HSA-9688162) RB1 L542Kfs11 [cytosol] (R-HSA-9688163) RB1 F482Sfs10 [cytosol] (R-HSA-9688188) RB1 L797* [cytosol] (R-HSA-9688189) RB1 P250Afs16 [cytosol] (R-HSA-9688190) RB1 S194Ffs7 [cytosol] (R-HSA-9688191) RB1 N623Qfs15 [cytosol] (R-HSA-9688184) RB1 T9Rfs56 [cytosol] (R-HSA-9688185) RB1 Y813Qfs10 [cytosol] (R-HSA-9688187) RB1 I768Cfs23 [cytosol] (R-HSA-9688180) RB1 L477Mfs17 [cytosol] (R-HSA-9688181) RB1 E675 [cytosol] (R-HSA-9662581) RB1 V654Cfs4 [cytosol] (R-HSA-9688182) RB1 F650Lfs5 [cytosol] (R-HSA-9688183) RB1 P39Sfs10 [cytosol] (R-HSA-9688176) RB1 H281Sfs2 [cytosol] (R-HSA-9688177) RB1 E551* [cytosol] (R-HSA-9662577) RB1 C61Vfs4 [cytosol] (R-HSA-9688178) RB1 D145Ifs8 [cytosol] (R-HSA-9688179) RB1 M148Hfs9 [cytosol] (R-HSA-9688140) RB1 E837 [cytosol] (R-HSA-9662540) RB1 L158Mfs19 [cytosol] (R-HSA-9688141) RB1 L832Ffs5 [cytosol] (R-HSA-9688142) RB1 E440* [cytosol] (R-HSA-9662542) RB1 D224Afs40 [cytosol] (R-HSA-9688136) RB1 P822Qfs4 [cytosol] (R-HSA-9688137) RB1 M148Vfs8 [cytosol] (R-HSA-9688138) RB1 L670Cfs7 [cytosol] (R-HSA-9688139) RB1 E465* [cytosol] (R-HSA-9662532) RB1 S414Kfs14 [cytosol] (R-HSA-9688133) RB1 K548Nfs3 [cytosol] (R-HSA-9688134) RB1 L135Tfs5 [cytosol] (R-HSA-9688135) RB1 Q207Tfs5 [cytosol] (R-HSA-9688128) RB1 Q384Tfs11 [cytosol] (R-HSA-9688129) RB1 L797Ffs14 [cytosol] (R-HSA-9688130) RB1 P232Rfs4 [cytosol] (R-HSA-9688131) RB1 T497Hfs22 [cytosol] (R-HSA-9688156) RB1 E817* [cytosol] (R-HSA-9662556) RB1 N367* [cytosol] (R-HSA-9688157) RB1 L809Rfs17 [cytosol] (R-HSA-9688158) RB1 E693 [cytosol] (R-HSA-9662558) RB1 K80* [cytosol] (R-HSA-9661534) RB1 W99Lfs11 [cytosol] (R-HSA-9688159) RB1 A15Pfs3 [cytosol] (R-HSA-9688152) RB1 Y239Lfs25 [cytosol] (R-HSA-9688153) RB1 D571Lfs41 [cytosol] (R-HSA-9688154) RB1 N186Ifs6 [cytosol] (R-HSA-9688155) RB1 E837Dfs12 [cytosol] (R-HSA-9688148) RB1 E672* [cytosol] (R-HSA-9662548) RB1 H483Yfs9 [cytosol] (R-HSA-9688149) RB1 R775Gfs35 [cytosol] (R-HSA-9688150) RB1 E580* [cytosol] (R-HSA-9662550) RB1 G617Rfs36 [cytosol] (R-HSA-9688151) RB1 E492 [cytosol] (R-HSA-9662551) RB1 A333Ffs13 [cytosol] (R-HSA-9688144) RB1 L564Sfs47 [cytosol] (R-HSA-9688145) RB1 D156Vfs19 [cytosol] (R-HSA-9688147) RB1 C438Vfs19 [cytosol] (R-HSA-9688108) RB1 C278* [cytosol] (R-HSA-9688109) RB1 E209Vfs3 [cytosol] (R-HSA-9688110) RB1 T116Lfs8 [cytosol] (R-HSA-9688111) RB1 R698Afs22 [cytosol] (R-HSA-9688104) RB1 V419 [cytosol] (R-HSA-9688105) RB1 I415Nfs13 [cytosol] (R-HSA-9688106) RB1 Y173Ffs11 [cytosol] (R-HSA-9688107) RB1 N133Tfs3 [cytosol] (R-HSA-9688100) RB1 M695Rfs10 [cytosol] (R-HSA-9688101) RB1 R418Sfs9 [cytosol] (R-HSA-9688102) RB1 Q689 [cytosol] (R-HSA-9662502) RB1 A74Efs4 [cytosol] (R-HSA-9688103) RB1 W99Yfs5 [cytosol] (R-HSA-9688096) RB1 G442Dfs15 [cytosol] (R-HSA-9688097) RB1 N258Efs11 [cytosol] (R-HSA-9688098) RB1 S182Ifs3 [cytosol] (R-HSA-9688099) RB1 Q436 [cytosol] (R-HSA-9662499) RB1 Q395Pfs11 [cytosol] (R-HSA-9688124) RB1 Y606Lfs47 [cytosol] (R-HSA-9688125) RB1 E539* [cytosol] (R-HSA-9662525) RB1 L317* [cytosol] (R-HSA-9688126) RB1 F104Lfs7 [cytosol] (R-HSA-9688127) RB1 E691 [cytosol] (R-HSA-9662527) RB1 D340Yfs5 [cytosol] (R-HSA-9688120) RB1 K740Tfs10 [cytosol] (R-HSA-9688121) RB1 H483Ifs12 [cytosol] (R-HSA-9688122) RB1 R611Lfs43 [cytosol] (R-HSA-9688123) RB1 V291Ifs9 [cytosol] (R-HSA-9688116) RB1 N133 [cytosol] (R-HSA-9688117) RB1 R334* [cytosol] (R-HSA-9688118) RB1 D697Qfs23 [cytosol] (R-HSA-9688119) RB1 L647Ffs5 [cytosol] (R-HSA-9688112) RB1 I723Nfs28 [cytosol] (R-HSA-9688113) RB1 L486Ifs6 [cytosol] (R-HSA-9688114) RB1 S565* [cytosol] (R-HSA-9688115) RB1 Y529Tfs3 [cytosol] (R-HSA-9688076) RB1 Q631 [cytosol] (R-HSA-9662476) RB1 S318Nfs13 [cytosol] (R-HSA-9688077) RB1 D856Efs17 [cytosol] (R-HSA-9688078) RB1 P595Lfs16 [cytosol] (R-HSA-9688079) RB1 P777Lfs33 [cytosol] (R-HSA-9688072) RB1 G310Dfs22 [cytosol] (R-HSA-9688073) RB1 P250Sfs20 [cytosol] (R-HSA-9688074) RB1 Q850* [cytosol] (R-HSA-9662474) RB1 I124Rfs6 [cytosol] (R-HSA-9688075) RB1 Q702 [cytosol] (R-HSA-9662475) RB1 E748Dfs6 [cytosol] (R-HSA-9688068) RB1 Q736 [cytosol] (R-HSA-9662468) RB1 R798Qfs4 [cytosol] (R-HSA-9688069) RB1 S588Ffs6 [cytosol] (R-HSA-9688070) RB1 K574* [cytosol] (R-HSA-9688071) RB1 D156Mfs19 [cytosol] (R-HSA-9688064) RB1 Y771Cfs23 [cytosol] (R-HSA-9688065) RB1 I66Dfs44 [cytosol] (R-HSA-9688066) RB1 Q685 [cytosol] (R-HSA-9662466) RB1 E125Kfs11 [cytosol] (R-HSA-9688067) RB1 Y655Lfs13 [cytosol] (R-HSA-9688092) RB1 R828Kfs10 [cytosol] (R-HSA-9688093) RB1 Y659Ifs4 [cytosol] (R-HSA-9688094) RB1 Q846* [cytosol] (R-HSA-9662494) RB1 E97Nfs14 [cytosol] (R-HSA-9688095) RB1 Q770 [cytosol] (R-HSA-9662495) RB1 C666* [cytosol] (R-HSA-9688088) RB1 Q471* [cytosol] (R-HSA-9662488) RB1 R71Efs39 [cytosol] (R-HSA-9688089) RB1 Q504 [cytosol] (R-HSA-9662489) RB1 R798Tfs17 [cytosol] (R-HSA-9688090) RB1 Q639 [cytosol] (R-HSA-9662490) RB1 N328* [cytosol] (R-HSA-9688091) RB1 S576Rfs34 [cytosol] (R-HSA-9688084) RB1 T726Nfs25 [cytosol] (R-HSA-9688085) RB1 Q597* [cytosol] (R-HSA-9662485) RB1 I532Nfs57 [cytosol] (R-HSA-9688086) RB1 K577Rfs34 [cytosol] (R-HSA-9688087) RB1 R73Sfs36 [cytosol] (R-HSA-9688080) RB1 E413Kfs4 [cytosol] (R-HSA-9688081) RB1 K844Sfs5 [cytosol] (R-HSA-9688082) RB1 A17Pfs3 [cytosol] (R-HSA-9688083) RB1 Q395* [cytosol] (R-HSA-9660655) RB1 L523* [cytosol] (R-HSA-9662176) RB1 R251* [cytosol] (R-HSA-9660640) RB1 L389* [cytosol] (R-HSA-9662178) RB1 Q217* [cytosol] (R-HSA-9660668) RB1 Q344* [cytosol] (R-HSA-9660669) RB1 S634* [cytosol] (R-HSA-9662207) RB1 S565* [cytosol] (R-HSA-9662200) RB1 S397* [cytosol] (R-HSA-9662202) RB1 S838* [cytosol] (R-HSA-9662203) RB1 R556* [cytosol] (R-HSA-9660661) RB1 R787* [cytosol] (R-HSA-9660656) RB1 G304* [cytosol] (R-HSA-9662152) RB1 W516* [cytosol] (R-HSA-9662660) RB1 W681* [cytosol] (R-HSA-9662661) RB1 E322* [cytosol] (R-HSA-9662149) RB1 W563* [cytosol] (R-HSA-9662656) RB1 L550* [cytosol] (R-HSA-9662173) RB1 R552* [cytosol] (R-HSA-9660637) RB1 L512* [cytosol] (R-HSA-9662168) RB1 R455* [cytosol] (R-HSA-9660632) RB1 R763* [cytosol] (R-HSA-9662681) RB1 L779* [cytosol] (R-HSA-9662169) RB1 R445* [cytosol] (R-HSA-9660633) RB1 R544* [cytosol] (R-HSA-9662677) RB1 R320* [cytosol] (R-HSA-9660630) RB1 L832* [cytosol] (R-HSA-9662167) RB1 Y498* [cytosol] (R-HSA-9662634) RB1 Y446* [cytosol] (R-HSA-9662628) RB1 Y655* [cytosol] (R-HSA-9662629) RB1 E323* [cytosol] (R-HSA-9662142) RB1 E364* [cytosol] (R-HSA-9662143) RB1 C489* [cytosol] (R-HSA-9662649) RB1 G310* [cytosol] (R-HSA-9662137) RB1 L335* [cytosol] (R-HSA-9662139) RB1 E313* [cytosol] (R-HSA-9662133) RB1 E315* [cytosol] (R-HSA-9662131) RB1 D479Vfs14 [cytosol] (R-HSA-9688204) RB1 C489Lfs5 [cytosol] (R-HSA-9688205) RB1 Y454* [cytosol] (R-HSA-9662605) RB1 E137Rfs3 [cytosol] (R-HSA-9688206) RB1 L676Ffs16 [cytosol] (R-HSA-9688207) RB1 Y728* [cytosol] (R-HSA-9662607) RB1 I799Ffs11 [cytosol] (R-HSA-9688200) RB1 D346Vfs17 [cytosol] (R-HSA-9688201) RB1 F514Pfs8 [cytosol] (R-HSA-9688202) RB1 N593Sfs5 [cytosol] (R-HSA-9688203) RB1 T58Yfs52 [cytosol] (R-HSA-9688196) RB1 N522Ifs2 [cytosol] (R-HSA-9688197) RB1 C553Vfs58 [cytosol] (R-HSA-9688198) RB1 P609Cfs43 [cytosol] (R-HSA-9688199) RB1 N269* [cytosol] (R-HSA-9688192) RB1 E287Rfs2 [cytosol] (R-HSA-9688193) RB1 E492Lfs4 [cytosol] (R-HSA-9688194) RB1 Q383Nfs3 [cytosol] (R-HSA-9688195) RB1 Y606 [cytosol] (R-HSA-9662617) RB1 Y756* [cytosol] (R-HSA-9662619) RB1 Y790* [cytosol] (R-HSA-9662612) RB1 T502Nfs17 [cytosol] (R-HSA-9688208) RB1 Y709 [cytosol] (R-HSA-9662608) RB1 Y749* [cytosol] (R-HSA-9662611) RB1 T738_R775del [nucleoplasm] (R-HSA-9661042) RB1 [cytosol] (R-HSA-9660621) hyperphosphorylated RB1 [nucleoplasm] (R-HSA-188389) p-S249-RB1 [nucleoplasm] (R-HSA-9687343) p-S230-RB1 [nucleoplasm] (R-HSA-9687336) p-T356-RB1 [nucleoplasm] (R-HSA-9687339) p-T826-RB1 [nucleoplasm] (R-HSA-9687334) p-S252-RB1 [nucleoplasm] (R-HSA-9687335) p-S807-RB1 [nucleoplasm] (R-HSA-9687356) p-T821-RB1 [nucleoplasm] (R-HSA-9687357) p-S795-RB1 [nucleoplasm] (R-HSA-69226) p-S612-RB1 [nucleoplasm] (R-HSA-9687352) p-S780-RB1 [nucleoplasm] (R-HSA-9687353) p-S811-RB1 [nucleoplasm] (R-HSA-9687354) RB1 [nucleoplasm] (R-HSA-68642) p-S788-RB1 [nucleoplasm] (R-HSA-9687347) p-S608-RB1 [nucleoplasm] (R-HSA-9687351) p-T373-RB1 [nucleoplasm] (R-HSA-9687355)	0.734	5
UniProt:P19338 NCL	1	NCL [nucleoplasm] (R-HSA-6791213)	0.71	8
UniProt:P68104 EEF1A1	7	EEF1A1 [cytosol] (R-HSA-156905) EEF1A1 [lysosomal membrane] (R-HSA-9626022) EEF1A1 [secretory granule lumen] (R-HSA-6801479) EEF1A1 [extracellular region] (R-HSA-6806456) EEF1A1 [ficolin-1-rich granule lumen] (R-HSA-6801528) Me3K318-EEF1A1 [cytosol] (R-HSA-8932419) Me3K79-EEF1A1 [cytosol] (R-HSA-8932212)	0.709	9
UniProt:P32121 ARRB2	2	PolyUb-ARRB2 [cytosol] (R-HSA-6783000) ARRB2 [cytosol] (R-HSA-416464)	0.708	5
UniProt:P06748 NPM1	5	p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [cytosol] (R-HSA-3008211) NPM1 [nucleoplasm] (R-HSA-606320) SUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) SUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.697	5
UniProt:P23396 RPS3	2	RPS3 [cytosol] (R-HSA-72369) RPS3 [nucleoplasm] (R-HSA-6798714)	0.696	8
UniProt:P29067	2	Arrb2 [cytosol] (R-RNO-416464) Arrb2 [cytosol] (R-RNO-6783000)	0.688	4
UniProt:P46777 RPL5	1	RPL5 [cytosol] (R-HSA-72482)	0.669	5
UniProt:O96017 CHEK2	3	p-T68-CHEK2 [nucleoplasm] (R-HSA-113825) p-S,3T-CHEK2 [nucleoplasm] (R-HSA-5683784) CHEK2 [nucleoplasm] (R-HSA-113824)	0.66	6
UniProt:P49407 ARRB1	5	PolyUb-ARRB1 [cytosol] (R-HSA-6783186) ARRB1 [cytosol] (R-HSA-264470) ARRB1 [lysosomal membrane] (R-HSA-432701) ARRB1 [Golgi membrane] (R-HSA-350831) ARRB1 [cytoplasmic vesicle membrane] (R-HSA-351187)	0.641	3
UniProt:Q96FW1 OTUB1	2	OTUB1 [nucleoplasm] (R-HSA-6783242) OTUB1 [cytosol] (R-HSA-933411)	0.632	5
UniProt:P49757 NUMB	1	NUMB [plasma membrane] (R-HSA-443595)	0.623	6
UniProt:Q9H2X6 HIPK2	3	HIPK2 [nucleoplasm] (R-HSA-3215222) SUMO1-K32-HIPK2 [nucleoplasm] (R-HSA-4090405) p-HIPK2 [nucleoplasm] (R-HSA-6799375)	0.62	5
UniProt:Q71UM5 RPS27L	2	RPS27L [cytosol] (R-HSA-8868849) RPS27L [nucleoplasm] (R-HSA-6791197)	0.619	6
IntAct:EBI-15762335 PMI			0.618	3
UniProt:Q8N488 RYBP	1	RYBP [nucleoplasm] (R-HSA-8937975)	0.616	11
UniProt:P61289 PSME3	2	PSME3 [cytosol] (R-HSA-68816) PSME3 [nucleoplasm] (R-HSA-174310)	0.612	8
UniProt:P26447 S10A4			0.611	3
UniProt:P48730 CSNK1D	3	CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5685717) CSNK1D [nucleoplasm] (R-HSA-421305) CSNK1D [cytosol] (R-HSA-380315)	0.61	6
UniProt:P42574 CASP3	5	CASP3(176-277) [nucleoplasm] (R-HSA-211203) CASP3(29-175) [nucleoplasm] (R-HSA-211194) CASP3(1-277) [cytosol] (R-HSA-57021) CASP3(29-175) [cytosol] (R-HSA-141644) CASP3(176-277) [cytosol] (R-HSA-141646)	0.609	2
UniProt:P29590 PML	5	SUMO2-K65,K160,K490-PML [nucleoplasm] (R-HSA-3000423) SUMO3-K65,K160,K490-PML [nucleoplasm] (R-HSA-3000386) SUMO1-K65,160,490-PML [nucleoplasm] (R-HSA-3000440) PML [cytosol] (R-HSA-5624327) PML [nucleoplasm] (R-HSA-1031706)	0.609	6
IntAct:EBI-4399559 UBIQ			0.609	2
UniProt:P53350 PLK1	4	p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) PLK1 [nucleoplasm] (R-HSA-156720) p-T210-PLK1 [cytosol] (R-HSA-3000318) PLK1 [cytosol] (R-HSA-164603)	0.602	7
UniProt:P42677 RPS27	2	RPS27 [cytosol] (R-HSA-72361) RPS27 [nucleoplasm] (R-HSA-6791190)	0.602	5
UniProt:Q9Y297 BTRC	2	BTRC [nucleoplasm] (R-HSA-3361753) BTRC [cytosol] (R-HSA-174237)	0.591	9
UniProt:P08069 IGF1R	3	IGF1R(31-736) [plasma membrane] (R-HSA-2404169) IGF1R(741-1367) [plasma membrane] (R-HSA-2404180) p-Y1161,Y1165,Y1166-IGF1R(741-1367) [plasma membrane] (R-HSA-2404172)	0.589	2
UniProt:P61978 HNRNPK	2	HNRNPK [nucleoplasm] (R-HSA-71945) SUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.589	2
UniProt:P29590-5 PML			0.582	6
UniProt:P62829 RPL23	1	RPL23 [cytosol] (R-HSA-72430)	0.573	3
UniProt:O15350 TP73	3	TP73 [cytosol] (R-HSA-8957239) PolyUb-TP73 [cytosol] (R-HSA-8957256) TP73 [nucleoplasm] (R-HSA-6798094)	0.558	4
UniProt:P23297 S100A1	1	S100A1 [extracellular region] (R-HSA-6805991)	0.558	2
UniProt:P29034 S10A2			0.558	2
UniProt:Q13362 PPP2R5C	3	PPP2R5C [nucleoplasm] (R-HSA-3008946) p-S337-PPP2R5C [cytosol] (R-HSA-6811447) PPP2R5C [cytosol] (R-HSA-3008954)	0.558	5
UniProt:P06703 S10A6			0.558	2
UniProt:P04271 S100B	1	S100B [extracellular region] (R-HSA-879433)	0.558	2
UniProt:Q9NVN8 GNL3L			0.556	8
UniProt:O15297 PPM1D	1	PPM1D [nucleoplasm] (R-HSA-2562518)	0.544	4
UniProt:P60866 RPS20	2	RPS20 [cytosol] (R-HSA-72349) RPS20 [nucleoplasm] (R-HSA-6798727)	0.527	2
UniProt:P78352 DLG4	3	DLG4 [endocytic vesicle membrane] (R-HSA-416847) DLG4 [cytosol] (R-HSA-6794267) DLG4 [plasma membrane] (R-HSA-202135)	0.525	3
UniProt:P17535 JUND	1	JUND [nucleoplasm] (R-HSA-9009924)	0.524	3
UniProt:P15311 EZR	3	p-T567-EZR [cytosol] (R-HSA-374559) p-Y146,Y354-EZR [cytosol] (R-HSA-374572) EZR [cytosol] (R-HSA-9020826)	0.524	3
UniProt:Q9UKB1 FBXW11	1	FBXW11 [cytosol] (R-HSA-976035)	0.524	4
UniProt:Q13616 CUL1	3	CUL1 [nucleoplasm] (R-HSA-187551) G76-NEDD8-K720-CUL1 [cytosol] (R-HSA-8952519) CUL1 [cytosol] (R-HSA-174230)	0.524	3
UniProt:Q2HR73 VIRF4			0.524	2
UniProt:P48729-2 CSNK1A1			0.524	3
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.524	3
UniProt:Q92736 RYR2	1	RYR2 [sarcoplasmic reticulum membrane] (R-HSA-937283)	0.524	2
UniProt:P48729 CSNK1A1	2	CSNK1A1 [cilium] (R-HSA-5632507) CSNK1A1 [cytosol] (R-HSA-195263)	0.524	3
UniProt:Q5T7V8 GORAB			0.524	6
UniProt:P49674 CSNK1E	2	CSNK1E [nucleoplasm] (R-HSA-421306) CSNK1E [cytosol] (R-HSA-205877)	0.524	3
UniProt:Q15466 NR0B2	1	NR0B2 [nucleoplasm] (R-HSA-376312)	0.524	4
UniProt:P05412 JUN	4	p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [nucleoplasm] (R-HSA-450250) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.524	3
UniProt:P03372 ESR1	8	SUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) Me260-ESR1 [cytosol] (R-HSA-9632177) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.508	2
UniProt:Q00688 FKBP3			0.508	2
UniProt:Q6PCD5 RFWD3			0.499	2
UniProt:Q9NS23 RASF1			0.499	5
UniProt:Q6P5F9	2	Xpo1 [cytosol] (R-MMU-165539) Xpo1 [nucleoplasm] (R-MMU-165529)	0.499	4
UniProt:Q13362-1 PPP2R5C			0.499	3
UniProt:P0C6X5-PRO_0000283876 REP			0.463	3
IntAct:EBI-1800051 CDKN1A			0.462	2

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