Nuclear Events (kinase and transcription factor activation)

Stable Identifier
R-HSA-198725
DOI
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this pathway in the Pathway Browser
An important function of the kinase cascade triggered by neurotrophins is to induce the phosphorylation and activation of transcription factors in the nucleus to initiate new programs of gene expression. Transcription factors directly activated by neurotrophin signalling are responsible for induction of immediate-early genes, many of which are transcription factors. These in turn are involved in the induction of delayed-early genes.
Literature References
PubMed ID Title Journal Year
8833451 Intracellular signaling pathways activated by neurotrophic factors

Segal, RA, Greenberg, ME

Annu Rev Neurosci 1996
Participants
Participates
Orthologous Events
Authored
Reviewed
Created
Cite Us!