Fc gamma receptors interact with antigen-bound IgG

Stable Identifier
R-HSA-199161
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, extracellular region
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Fc gamma receptors interact with antigen-bound IgG
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Most cells of the immune system express receptors for the Fc region of IgG. This heterogeneous family of molecules plays a critical role in immunity, by linking the humoral to the cellular responses. NK cells and B cells have been shown to express exclusively Fc-gamma RIIIa and RIIb respectively.

Literature References
PubMed ID Title Journal Year
11955599 Recognition of immunoglobulins by Fcgamma receptors

Radaev, S, Sun, P

Mol Immunol 2002
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
Fc gamma receptors interact with antigen-bound IgG (Canis familiaris)
Fc gamma receptors interact with antigen-bound IgG (Danio rerio)
Fc gamma receptors interact with antigen-bound IgG (Mus musculus)
Fc gamma receptors interact with antigen-bound IgG (Rattus norvegicus)
Fc gamma receptors interact with antigen-bound IgG (Sus scrofa)
Fc gamma receptors interact with antigen-bound IgG (Xenopus tropicalis)
Authored
de Bono, B  (2007-07-08)
Reviewed
Trowsdale, J  (2007-08-07)
Barrow, AD  (2015-05-13)
Created
de Bono, B  (2007-07-08)