Reactome: A Curated Pathway Database

Fc gamma receptors interact with antigen-bound IgG

Stable Identifier
R-HSA-199161
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Most cells of the immune system express receptors for the Fc region of IgG. This heterogeneous family of molecules plays a critical role in immunity, by linking the humoral to the cellular responses. NK cells and B cells have been shown to express exclusively Fc-gamma RIIIa and RIIb respectively.

Literature References
PubMed ID Title Journal Year
Participants
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