AKT can phosphorylate RSK

Stable Identifier
R-HSA-199839
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Ribosomal protein S6 kinase beta-2 (RSK) activation is a highly conserved mitogenic response, and the activities of RSK are stimulated by multiple serine/threonine phosphorylations by different upstream kinases, one of which is AKT.

Literature References
PubMed ID Title Journal Year
10490848 Cloning and characterization of a nuclear S6 kinase, S6 kinase-related kinase (SRK); a novel nuclear target of Akt

Kim, JW, Kim, J, Lee, B, Chung, J, Koh, H, Kim, D, Yun, YH, Choi, HS, Jee, K

Oncogene 1999
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Participates
Event Information
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Catalyst Activity

protein serine/threonine kinase activity of p-T,p-S-AKT [nucleoplasm]

Orthologous Events
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