MSK1 activates CREB

Stable Identifier
R-HSA-199935
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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MSK1 is required for the mitogen-induced phosphorylation of the transcription factor, cAMP response element-binding protein (CREB).

Literature References
PubMed ID Title Journal Year
9687510 Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

Deak, M, Clifton, AD, Lucocq, LM, Alessi, DR

EMBO J 1998
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of p-S212,S360,S376,T581-RPS6KA5 [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created