Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
COPG1 [cytosol]
Stable Identifier
R-HSA-199987
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Coatomer gamma subunit
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
Active ARF recruits coatomer (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
Active ARF recruits coatomer (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Golgi-to-ER retrograde transport (Homo sapiens)
COPI-dependent Golgi-to-ER retrograde traffic (Homo sapiens)
ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
Active ARF recruits coatomer to the Golgi (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
COPI vesicle uncoating at the ER (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y678 COPG1
Gene Names
COPG1, COPG
Chain
chain:1-874
Reference Genes
BioGPS Gene:22820 COPG1
COSMIC (genes):COPG1 COPG1
CTD Gene:22820 COPG1
dbSNP Gene:22820 COPG1
ENSEMBL:ENSG00000181789 COPG1
ENSEMBL_homo_sapiens_GENE:ENSG00000181789.14 COPG1
HGNC:2236 COPG1
KEGG Gene (Homo sapiens):22820 COPG1
Monarch:22820 COPG1
NCBI Gene:22820 COPG1
OMIM:615525 COPG1
UCSC:Q9Y678 COPG1
Reference Transcript
RefSeq:NM_016128.3 COPG1
Other Identifiers
11716855_a_at
16945320
217749_PM_at
217749_at
22820
2641533
2641534
2641536
2641537
2641540
2641543
2641544
2641545
2641546
2641547
2641548
2641549
2641550
2641552
2641553
2641555
2641558
2641559
2641560
2641563
2641565
2641567
2641569
2641571
2641572
2641573
2641574
2641575
2641576
48785_at
48787_g_at
52810_at
8082478
A_14_P104366
A_23_P44617
GE55889
GO:0000139
GO:0005198
GO:0005515
GO:0005737
GO:0005783
GO:0005789
GO:0005793
GO:0005794
GO:0005829
GO:0006886
GO:0006888
GO:0006891
GO:0007018
GO:0009306
GO:0015031
GO:0016020
GO:0016192
GO:0030117
GO:0030126
GO:0030133
GO:0030663
GO:0031090
GO:0031410
GO:0043226
GO:0051683
GO:0072384
HMNXSV003003676
ILMN_1708204
PH_hs_0032886
TC03000689.hg
g11559928_3p_at
g11559928_3p_x_at
Participates
as a member of
COPG1,2 [cytosol] (Homo sapiens)
Other forms of this molecule
COPG1 [endoplasmic reticulum membrane]
COPG1 [Golgi membrane]
COPG1 [transport vesicle]
Inferred To
COPG1 [cytosol]
(Bos taurus)
COPG1 [cytosol]
(Canis familiaris)
COPG1 [cytosol]
(Gallus gallus)
COPG1 [cytosol]
(Plasmodium falciparum)
COPG1 [cytosol]
(Sus scrofa)
copg2 [cytosol]
(Danio rerio)
Copg1 [cytosol]
(Mus musculus)
Copg1 [cytosol]
(Rattus norvegicus)
SEC21 [cytosol]
(Saccharomyces cerevisiae)
copg1 [cytosol]
(Xenopus tropicalis)
gammaCOP [cytosol]
(Drosophila melanogaster)
copg-1 [cytosol]
(Caenorhabditis elegans)
sec21 [cytosol]
(Schizosaccharomyces pombe)
copG [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_057212.1
OpenTargets
ENSG00000181789
GeneCards
Q9Y678
HPA
ENSG00000181789-COPG1
Ensembl
ENSP00000325002
,
ENSG00000181789
,
ENST00000314797
PRO
Q9Y678
Pharos - Targets
Q9Y678
PDB
1R4X
HMDB Protein
HMDBP08335
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.788
21
UniProt:Q9NTJ5 SACM1L
2
SACM1L [endoplasmic reticulum membrane]
(R-HSA-1604637)
SACM1L [Golgi membrane]
(R-HSA-1806242)
0.677
6
UniProt:P01106 MYC
2
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
MYC [nucleoplasm]
(R-HSA-188379)
0.564
2
UniProt:P04233 CD74
13
CD74(81-104) [lysosomal lumen]
(R-HSA-2213220)
CD74(81-104) [lysosomal membrane]
(R-HSA-2130446)
CD74(1-117) [lysosomal membrane]
(R-HSA-2130632)
CD74 [lumenal side of endoplasmic reticulum membrane]
(R-HSA-1181241)
CD74 [ER to Golgi transport vesicle membrane]
(R-HSA-2130456)
CD74 [Golgi membrane]
(R-HSA-2214388)
CD74 [trans-Golgi network membrane]
(R-HSA-2130493)
CD74 [transport vesicle membrane]
(R-HSA-2130624)
CD74 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130522)
CD74 [endocytic vesicle membrane]
(R-HSA-2130460)
CD74(1-176) [lysosomal membrane]
(R-HSA-2130602)
CD74 [lysosomal membrane]
(R-HSA-2130320)
CD74 [plasma membrane]
(R-HSA-2130666)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
